De novo design of luciferases using deep learning AHW Yeh, C Norn, Y Kipnis, D Tischer, SJ Pellock, D Evans, P Ma, ... Nature 614 (7949), 774-780, 2023 | 273 | 2023 |
Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis SD Khare, Y Kipnis, PJ Greisen, R Takeuchi, Y Ashani, M Goldsmith, ... Nature chemical biology 8 (3), 294-300, 2012 | 257 | 2012 |
Improving protein expression, stability, and function with ProteinMPNN KH Sumida, R Núñez-Franco, I Kalvet, SJ Pellock, BIM Wicky, LF Milles, ... Journal of the American Chemical Society 146 (3), 2054-2061, 2024 | 88 | 2024 |
Exploration of alternate catalytic mechanisms and optimization strategies for retroaldolase design S Bjelic, Y Kipnis, L Wang, Z Pianowski, S Vorobiev, M Su, ... Journal of molecular biology 426 (1), 256-271, 2014 | 43 | 2014 |
A computational method for design of connected catalytic networks in proteins BD Weitzner, Y Kipnis, AG Daniel, D Hilvert, D Baker Protein Science 28 (12), 2036-2041, 2019 | 41 | 2019 |
TRINS: a method for gene modification by randomized tandem repeat insertions Y Kipnis, E Dellus-Gur, DS Tawfik Protein Engineering, Design & Selection 25 (9), 437-444, 2012 | 31 | 2012 |
Small molecule probes to quantify the functional fraction of a specific protein in a cell with minimal folding equilibrium shifts Y Liu, YL Tan, X Zhang, G Bhabha, DC Ekiert, JC Genereux, Y Cho, ... Proceedings of the National Academy of Sciences 111 (12), 4449-4454, 2014 | 27 | 2014 |
Concerted ATP-induced allosteric transitions in GroEL facilitate release of protein substrate domains in an all-or-none manner Y Kipnis, N Papo, G Haran, A Horovitz Proceedings of the National Academy of Sciences 104 (9), 3119-3124, 2007 | 26 | 2007 |
Comparison of designed and randomly generated catalysts for simple chemical reactions Y Kipnis, D Baker Protein science 21 (9), 1388-1395, 2012 | 24 | 2012 |
De Novo-Designed Enzymes as Small-Molecule-Regulated Fluorescence Imaging Tags and Fluorescent Reporters Y Liu, X Zhang, YL Tan, G Bhabha, DC Ekiert, Y Kipnis, S Bjelic, D Baker, ... Journal of the American Chemical Society 136 (38), 13102-13105, 2014 | 20 | 2014 |
Design and optimization of enzymatic activity in a de novo β‐barrel scaffold Y Kipnis, AO Chaib, AA Vorobieva, G Cai, G Reggiano, B Basanta, ... Protein Science 31 (11), e4405, 2022 | 17 | 2022 |
De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8 A Roy, L Shi, A Chang, X Dong, A Fernandez, JC Kraft, J Li, VQ Le, ... Nature Communications 14 (1), 5660, 2023 | 16 | 2023 |
Concerted release of substrate domains from GroEL by ATP is demonstrated with FRET N Papo, Y Kipnis, G Haran, A Horovitz Journal of molecular biology 380 (4), 717-725, 2008 | 16 | 2008 |
Design of an optical switch for studying conformational dynamics in individual molecules of GroEL GA Frank, Y Kipnis, E Smolensky, SS Daube, A Horovitz, G Haran Bioconjugate chemistry 19 (7), 1339-1341, 2008 | 13 | 2008 |
Modeling protein-small molecule conformational ensembles with ChemNet I Anishchenko, Y Kipnis, I Kalvet, G Zhou, R Krishna, SJ Pellock, A Lauko, ... bioRxiv, 2024 | | 2024 |
Design and optimization of enzymatic activity in a de novo-barrel scaffold Y Kipnis, AO Chaib, AA Vorobieva, G Cai, G Reggiano, B Basanta, ... | | 2022 |
HARNESSING BACKBONE STRAIN TO DESIGN BETA-BARREL PROTEINS DE NOVO: FROM FIRST PRINCIPLES TO APPLICATION A Vorobieva, J Dou, W Sheffler, B Mao, M Bick, L Doyle, J Klima, ... PROTEIN SCIENCE 28, 115-116, 2019 | | 2019 |
Blueprint for de novo protein design and engineering AO Chaib, Y Kipnis, D Baker, D Hilvert ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 258, 2019 | | 2019 |
Designing de novo retroaldolase catalysts Y Kipnis, D Baker | | 2019 |
Award Address (Nobel Laureate Signature Award for Graduate Education in Chemistry (Student) sponsored by Avantor Performance Materials). E. coli protein homeostasis network … X Zhang, Y Cho, ET Powers, M Singh, J Yates, Y Kipnis, D Baker, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 243, 2012 | | 2012 |