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Kathryn Tiller
Kathryn Tiller
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Advances in antibody design
KE Tiller, PM Tessier
Annual review of biomedical engineering 17, 191-216, 2015
3312015
Arginine mutations in antibody complementarity-determining regions display context-dependent affinity/specificity trade-offs
KE Tiller, L Li, S Kumar, MC Julian, S Garde, PM Tessier
Journal of Biological Chemistry 292 (40), 16638-16652, 2017
732017
Facile affinity maturation of antibody variable domains using natural diversity mutagenesis
KE Tiller, R Chowdhury, T Li, SD Ludwig, S Sen, CD Maranas, PM Tessier
Frontiers in Immunology 8, 2017
592017
Design and Optimization of Anti-amyloid Domain Antibodies Specific for β-Amyloid and Islet Amyloid Polypeptide
CC Lee, MC Julian, KE Tiller, F Meng, SE DuConge, R Akter, DP Raleigh, ...
Journal of Biological Chemistry 291 (6), 2858-2873, 2016
512016
Co-evolution of affinity and stability of grafted amyloid-motif domain antibodies
MC Julian, CC Lee, KE Tiller, LA Rabia, EK Day, AJ Schick III, PM Tessier
Protein Engineering, Design and Selection 28 (10), 339-350, 2015
432015
Conformational stability as a design target to control protein aggregation
JA Costanzo, CJ O'brien, K Tiller, E Tamargo, AS Robinson, CJ Roberts, ...
Protein Engineering, Design & Selection 27 (5), 157-167, 2014
342014
Computational Biology: Lifting the veil on amyloid drug design
KE Tiller, PM Tessier
Elife 2, e01089, 2013
62013
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