| Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomas L Zhang, LH Chen, H Wan, R Yang, Z Wang, J Feng, S Yang, S Jones, ... Nature genetics 46 (7), 726-730, 2014 | 195 | 2014 |
| The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma BH Diplas, X He, JA Brosnan-Cashman, H Liu, LH Chen, Z Wang, ... Nature communications 9 (1), 2087, 2018 | 165 | 2018 |
| KMT2D maintains neoplastic cell proliferation and global histone H3 lysine 4 monomethylation C Guo, LH Chen, Y Huang, CC Chang, P Wang, CJ Pirozzi, X Qin, X Bao, ... Oncotarget 4 (11), 2144, 2013 | 159 | 2013 |
| Global identification of MLL2-targeted loci reveals MLL2’s role in diverse signaling pathways C Guo, CC Chang, M Wortham, LH Chen, DN Kernagis, X Qin, YW Cho, ... Proceedings of the National Academy of Sciences 109 (43), 17603-17608, 2012 | 114 | 2012 |
| The integrated genomic and epigenomic landscape of brainstem glioma LH Chen, C Pan, BH Diplas, C Xu, LJ Hansen, Y Wu, X Chen, Y Geng, ... Nature communications 11 (1), 3077, 2020 | 71 | 2020 |
| Cic Loss Promotes Gliomagenesis via Aberrant Neural Stem Cell Proliferation and Differentiation R Yang, LH Chen, LJ Hansen, AB Carpenter, CJ Moure, H Liu, CJ Pirozzi, ... Cancer research 77 (22), 6097-6108, 2017 | 57 | 2017 |
| Mutant IDH1 disrupts the mouse subventricular zone and alters brain tumor progression CJ Pirozzi, AB Carpenter, MS Waitkus, CY Wang, H Zhu, LJ Hansen, ... Molecular Cancer Research 15 (5), 507-520, 2017 | 51 | 2017 |
| MTAP loss promotes stemness in glioblastoma and confers unique susceptibility to purine starvation LJ Hansen, R Sun, R Yang, SX Singh, LH Chen, CJ Pirozzi, CJ Moure, ... Cancer research 79 (13), 3383-3394, 2019 | 44 | 2019 |
| Mutant IDH1 is required for IDH1 mutated tumor cell growth G Jin, CJ Pirozzi, LH Chen, GY Lopez, CG Duncan, J Feng, I Spasojevic, ... Oncotarget 3 (8), 774, 2012 | 41 | 2012 |
| Identification of prognostic genes for recurrent risk prediction in triple negative breast cancer patients in Taiwan LH Chen, WH Kuo, MH Tsai, PC Chen, CK Hsiao, EY Chuang, LY Chang, ... PloS one 6 (11), e28222, 2011 | 41 | 2011 |
| Targeting mutant PPM1D sensitizes diffuse intrinsic pontine glioma cells to the PARP inhibitor olaparib Z Wang, C Xu, BH Diplas, CJ Moure, CPJ Chen, LH Chen, C Du, H Zhu, ... Molecular Cancer Research 18 (7), 968-980, 2020 | 27 | 2020 |
| MTAP loss correlates with an immunosuppressive profile in GBM and its substrate MTA stimulates alternative macrophage polarization LJ Hansen, R Yang, K Roso, W Wang, L Chen, Q Yang, CJ Pirozzi, Y He Scientific Reports 12 (1), 4183, 2022 | 25 | 2022 |
| CRISPR editing of mutant IDH1 R132H induces a CpG methylation-low state in patient-derived glioma models of G-CIMP CJ Moure, BH Diplas, LH Chen, R Yang, CJ Pirozzi, Z Wang, I Spasojevic, ... Molecular Cancer Research 17 (10), 2042-2050, 2019 | 25 | 2019 |
| SNP rs10248565 in HDAC9 as a novel genomic aberration biomarker of lung adenocarcinoma in non-smoking women LC Lai, MH Tsai, PC Chen, LH Chen, JH Hsiao, SK Chen, TP Lu, JM Lee, ... Journal of biomedical science 21, 1-9, 2014 | 17 | 2014 |
| TP53 wild-type/PPM1D mutant diffuse intrinsic pontine gliomas are sensitive to a MDM2 antagonist C Xu, H Liu, CJ Pirozzi, LH Chen, PK Greer, BH Diplas, L Zhang, ... Acta Neuropathologica Communications 9, 1-12, 2021 | 13 | 2021 |
| Imaging biomarkers of TERT or GABPB1 silencing in TERT-positive glioblastoma N Minami, D Hong, N Stevers, CJ Barger, M Radoul, C Hong, L Chen, ... Neuro-oncology 24 (11), 1898-1910, 2022 | 9 | 2022 |
| Challenges in the discovery of tumor-specific alternative splicing-derived cell-surface antigens in glioma T Nejo, L Wang, KK Leung, A Wang, S Lakshmanachetty, M Gallus, ... Scientific Reports 14 (1), 6362, 2024 | 8 | 2024 |
| Purine synthesis inhibitor L-alanosine impairs mitochondrial function and stemness of brain tumor initiating cells SX Singh, R Yang, K Roso, LJ Hansen, C Du, LH Chen, PK Greer, ... Biomedicines 10 (4), 751, 2022 | 8 | 2022 |
| The genomic landscape of TERT promoter wildtype-IDH wildtype glioblastoma. Nat Commun 9: 2087 BH Diplas, X He, JA Brosnan-Cashman, H Liu, LH Chen, Z Wang, ... | 8 | 2018 |
| Mutant allele quantification reveals a genetic basis for TP53 mutation-driven castration resistance in prostate cancer cells K Lei, R Sun, LH Chen, BH Diplas, CJ Moure, W Wang, LJ Hansen, Y Tao, ... Scientific Reports 8 (1), 12507, 2018 | 6 | 2018 |
