Impaired on/off regulation of TNF biosynthesis in mice lacking TNF AU-rich elements: implications for joint and gut-associated immunopathologies D Kontoyiannis, M Pasparakis, TT Pizarro, F Cominelli, G Kollias Immunity 10 (3), 387-398, 1999 | 1713 | 1999 |
TNF-α induction by LPS is regulated posttranscriptionally via a Tpl2/ERK-dependent pathway CD Dumitru, JD Ceci, C Tsatsanis, D Kontoyiannis, K Stamatakis, JH Lin, ... Cell 103 (7), 1071-1083, 2000 | 1037 | 2000 |
MK2 targets AU-rich elements and regulates biosynthesis of tumor necrosis factor and interleukin-6 independently at different post-transcriptional levels A Neininger, D Kontoyiannis, A Kotlyarov, R Winzen, R Eckert, HD Volk, ... Journal of Biological Chemistry 277 (5), 3065-3068, 2002 | 510 | 2002 |
Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases M Armaka, M Apostolaki, P Jacques, DL Kontoyiannis, D Elewaut, ... Journal of Experimental Medicine 205 (2), 331-337, 2008 | 414 | 2008 |
On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease G Kollias, E Douni, G Kassiotis, D Kontoyiannis Immunological reviews 169 (1), 175-194, 1999 | 383 | 1999 |
Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor–induced Crohn's-like inflammatory bowel disease D Kontoyiannis, G Boulougouris, M Manoloukos, M Armaka, M Apostolaki, ... The Journal of experimental medicine 196 (12), 1563-1574, 2002 | 345 | 2002 |
Interleukin‐10 targets p38 MAPK to modulate ARE‐dependent TNF mRNA translation and limit intestinal pathology D Kontoyiannis, A Kotlyarov, E Carballo, L Alexopoulou, PJ Blackshear, ... The EMBO journal, 2001 | 325 | 2001 |
HuR as a negative posttranscriptional modulator in inflammation V Katsanou, O Papadaki, S Milatos, PJ Blackshear, P Anderson, G Kollias, ... Molecular cell 19 (6), 777-789, 2005 | 297 | 2005 |
Transgenic mice expressing the human inducible Hsp70 have hippocampal neurons resistant to ischemic injury JCL Plumier, AM Krueger, RW Currie, D Kontoyiannis, G Kollias, ... Cell stress & chaperones 2 (3), 162, 1997 | 286 | 1997 |
The function of tumour necrosis factor and receptors in models of multi-organ inflammation, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease G Kollias, E Douni, G Kassiotis, D Kontoyiannis Annals of the rheumatic diseases 58, I32-I39, 1999 | 257* | 1999 |
Role of TNF/TNFR in autoimmunity: specific TNF receptor blockade may be advantageous to anti-TNF treatments G Kollias, D Kontoyiannis Cytokine & growth factor reviews 13 (4-5), 315-321, 2002 | 245 | 2002 |
The RNA-binding protein Elavl1/HuR is essential for placental branching morphogenesis and embryonic development V Katsanou, S Milatos, A Yiakouvaki, N Sgantzis, A Kotsoni, M Alexiou, ... Molecular and cellular biology 29 (10), 2762-2776, 2009 | 236 | 2009 |
Post-transcriptional coordination of immunological responses by RNA-binding proteins P Kafasla, A Skliris, DL Kontoyiannis Nature immunology 15 (6), 492-502, 2014 | 208 | 2014 |
The RNA-binding protein HuR is essential for the B cell antibody response MD Diaz-Muñoz, SE Bell, K Fairfax, E Monzon-Casanova, ... Nature immunology 16 (4), 415-425, 2015 | 180 | 2015 |
ATX expression and LPA signalling are vital for the development of the nervous system S Fotopoulou, N Oikonomou, E Grigorieva, I Nikitopoulou, T Paparountas, ... Developmental biology 339 (2), 451-464, 2010 | 179 | 2010 |
Accelerated autoimmunity and lupus nephritis in NZB mice with an engineered heterozygous deficiency in tumor necrosis factor D Kontoyiannis, G Kollias European journal of immunology 30 (7), 2038-2047, 2000 | 175 | 2000 |
Transmembrane TNF protects mutant mice against intracellular bacterial infections, chronic inflammation and autoimmunity L Alexopoulou, K Kranidioti, S Xanthoulea, M Denis, A Kotanidou, ... European journal of immunology 36 (10), 2768-2780, 2006 | 172 | 2006 |
Transgenic and knockout analyses of the role of TNF in immune regulation and disease pathogenesis. E Douni, K Akassoglou, L Alexopoulou, S Georgopoulos, S Haralambous, ... Journal of inflammation 47 (1-2), 27-38, 1995 | 154 | 1995 |
Myeloid cell expression of the RNA-binding protein HuR protects mice from pathologic inflammation and colorectal carcinogenesis A Yiakouvaki, M Dimitriou, I Karakasiliotis, C Eftychi, S Theocharis, ... The Journal of clinical investigation 122 (1), 48-61, 2012 | 152 | 2012 |
Role of β7 integrin and the chemokine/chemokine receptor pair CCL25/CCR9 in modeled TNF-dependent Crohn's disease M Apostolaki, M Manoloukos, M Roulis, MA Wurbel, W Müller, ... Gastroenterology 134 (7), 2025-2035, 2008 | 123 | 2008 |