팔로우
Bret Sellman
Bret Sellman
Director, Discovery Microbiome, AstraZeneca
astrazeneca.com의 이메일 확인됨
제목
인용
인용
연도
Designing a polyvalent inhibitor of anthrax toxin
M Mourez, RS Kane, J Mogridge, S Metallo, P Deschatelets, BR Sellman, ...
nature biotechnology 19 (10), 958-961, 2001
4022001
A multifunctional bispecific antibody protects against Pseudomonas aeruginosa
A DiGiandomenico, AE Keller, C Gao, GJ Rainey, P Warrener, ...
Science translational medicine 6 (262), 262ra155-262ra155, 2014
3062014
Dominant-negative mutants of a toxin subunit: an approach to therapy of anthrax
BR Sellman, M Mourez, R John Collier
Science 292 (5517), 695-697, 2001
2712001
Differential expression and roles of Staphylococcus aureus virulence determinants during colonization and disease
A Jenkins, BA Diep, TT Mai, NH Vo, P Warrener, J Suzich, CK Stover, ...
MBio 6 (1), 10.1128/mbio. 02272-14, 2015
2042015
Assessment of an anti-alpha-toxin monoclonal antibody for prevention and treatment of Staphylococcus aureus-induced pneumonia
L Hua, JJ Hilliard, Y Shi, C Tkaczyk, LI Cheng, X Yu, V Datta, S Ren, ...
Antimicrobial agents and chemotherapy 58 (2), 1108-1117, 2014
2032014
Moving toward endotypes in atopic dermatitis: identification of patient clusters based on serum biomarker analysis
JL Thijs, I Strickland, CAFM Bruijnzeel-Koomen, S Nierkens, ...
Journal of Allergy and Clinical Immunology 140 (3), 730-737, 2017
1832017
Identification of anti-alpha toxin monoclonal antibodies that reduce the severity of Staphylococcus aureus dermonecrosis and exhibit a correlation between affinity and potency
C Tkaczyk, L Hua, R Varkey, Y Shi, L Dettinger, R Woods, A Barnes, ...
Clinical and vaccine immunology 19 (3), 377-385, 2012
1512012
α-Toxin induces platelet aggregation and liver injury during Staphylococcus aureus sepsis
BGJ Surewaard, A Thanabalasuriar, Z Zeng, C Tkaczyk, TS Cohen, ...
Cell host & microbe 24 (2), 271-284. e3, 2018
1422018
A novel anti-PcrV antibody providing enhanced protection against Pseudomonas aeruginosa in multiple animal infection models
P Warrener, R Varkey, JC Bonnell, A DiGiandomenico, M Camara, ...
Antimicrobial agents and chemotherapy 58 (8), 4384-4391, 2014
1382014
Point mutations in anthrax protective antigen that block translocation
BR Sellman, S Nassi, RJ Collier
Journal of biological chemistry 276 (11), 8371-8376, 2001
1272001
Staphylococcus aureus α toxin potentiates opportunistic bacterial lung infections
TS Cohen, JJ Hilliard, O Jones-Nelson, AE Keller, T O’Day, C Tkaczyk, ...
Science Translational Medicine 8 (329), 329ra31-329ra31, 2016
1262016
Antibacterial monoclonal antibodies: the next generation?
A DiGiandomenico, BR Sellman
Current opinion in microbiology 27, 78-85, 2015
1152015
Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source
ML Boland, D Oró, KS Tølbøl, ST Thrane, JC Nielsen, TS Cohen, ...
World journal of gastroenterology 25 (33), 4904, 2019
1062019
Mechanisms of neutralization of a human anti-α-toxin antibody
V Oganesyan, L Peng, MM Damschroder, L Cheng, A Sadowska, ...
Journal of Biological Chemistry 289 (43), 29874-29880, 2014
1032014
Mouse model of hematogenous implant-related Staphylococcus aureus biofilm infection reveals therapeutic targets
Y Wang, LI Cheng, DR Helfer, AG Ashbaugh, RJ Miller, AJ Tzomides, ...
Proceedings of the National Academy of Sciences 114 (26), E5094-E5102, 2017
1022017
S. aureus evades macrophage killing through NLRP3-dependent effects on mitochondrial trafficking
TS Cohen, ML Boland, BB Boland, V Takahashi, A Tovchigrechko, Y Lee, ...
Cell reports 22 (9), 2431-2441, 2018
982018
Staphylococcus aureus Alpha Toxin Suppresses Effective Innate and Adaptive Immune Responses in a Murine Dermonecrosis Model
C Tkaczyk, MM Hamilton, V Datta, XP Yang, JJ Hilliard, GL Stephens, ...
PLoS one 8 (10), e75103, 2013
982013
Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature
A Thanabalasuriar, BGJ Surewaard, ME Willson, AS Neupane, CK Stover, ...
The Journal of clinical investigation 127 (6), 2249-2261, 2017
932017
Candida albicans Augments Staphylococcus aureus Virulence by Engaging the Staphylococcal agr Quorum Sensing System
OA Todd, PL Fidel Jr, JM Harro, JJ Hilliard, C Tkaczyk, BR Sellman, ...
MBio 10 (3), 10.1128/mbio. 00910-19, 2019
922019
Generation of a membrane‐bound, oligomerized pre‐pore complex is necessary for pore formation by Clostridium septicum alpha toxin
BR Sellman, BL Kagan, RK Tweten
Molecular microbiology 23 (3), 551-558, 1997
901997
현재 시스템이 작동되지 않습니다. 나중에 다시 시도해 주세요.
학술자료 1–20