Designing a polyvalent inhibitor of anthrax toxin M Mourez, RS Kane, J Mogridge, S Metallo, P Deschatelets, BR Sellman, ... nature biotechnology 19 (10), 958-961, 2001 | 402 | 2001 |
A multifunctional bispecific antibody protects against Pseudomonas aeruginosa A DiGiandomenico, AE Keller, C Gao, GJ Rainey, P Warrener, ... Science translational medicine 6 (262), 262ra155-262ra155, 2014 | 306 | 2014 |
Dominant-negative mutants of a toxin subunit: an approach to therapy of anthrax BR Sellman, M Mourez, R John Collier Science 292 (5517), 695-697, 2001 | 271 | 2001 |
Differential expression and roles of Staphylococcus aureus virulence determinants during colonization and disease A Jenkins, BA Diep, TT Mai, NH Vo, P Warrener, J Suzich, CK Stover, ... MBio 6 (1), 10.1128/mbio. 02272-14, 2015 | 204 | 2015 |
Assessment of an anti-alpha-toxin monoclonal antibody for prevention and treatment of Staphylococcus aureus-induced pneumonia L Hua, JJ Hilliard, Y Shi, C Tkaczyk, LI Cheng, X Yu, V Datta, S Ren, ... Antimicrobial agents and chemotherapy 58 (2), 1108-1117, 2014 | 203 | 2014 |
Moving toward endotypes in atopic dermatitis: identification of patient clusters based on serum biomarker analysis JL Thijs, I Strickland, CAFM Bruijnzeel-Koomen, S Nierkens, ... Journal of Allergy and Clinical Immunology 140 (3), 730-737, 2017 | 183 | 2017 |
Identification of anti-alpha toxin monoclonal antibodies that reduce the severity of Staphylococcus aureus dermonecrosis and exhibit a correlation between affinity and potency C Tkaczyk, L Hua, R Varkey, Y Shi, L Dettinger, R Woods, A Barnes, ... Clinical and vaccine immunology 19 (3), 377-385, 2012 | 151 | 2012 |
α-Toxin induces platelet aggregation and liver injury during Staphylococcus aureus sepsis BGJ Surewaard, A Thanabalasuriar, Z Zeng, C Tkaczyk, TS Cohen, ... Cell host & microbe 24 (2), 271-284. e3, 2018 | 142 | 2018 |
A novel anti-PcrV antibody providing enhanced protection against Pseudomonas aeruginosa in multiple animal infection models P Warrener, R Varkey, JC Bonnell, A DiGiandomenico, M Camara, ... Antimicrobial agents and chemotherapy 58 (8), 4384-4391, 2014 | 138 | 2014 |
Point mutations in anthrax protective antigen that block translocation BR Sellman, S Nassi, RJ Collier Journal of biological chemistry 276 (11), 8371-8376, 2001 | 127 | 2001 |
Staphylococcus aureus α toxin potentiates opportunistic bacterial lung infections TS Cohen, JJ Hilliard, O Jones-Nelson, AE Keller, T O’Day, C Tkaczyk, ... Science Translational Medicine 8 (329), 329ra31-329ra31, 2016 | 126 | 2016 |
Antibacterial monoclonal antibodies: the next generation? A DiGiandomenico, BR Sellman Current opinion in microbiology 27, 78-85, 2015 | 115 | 2015 |
Towards a standard diet-induced and biopsy-confirmed mouse model of non-alcoholic steatohepatitis: Impact of dietary fat source ML Boland, D Oró, KS Tølbøl, ST Thrane, JC Nielsen, TS Cohen, ... World journal of gastroenterology 25 (33), 4904, 2019 | 106 | 2019 |
Mechanisms of neutralization of a human anti-α-toxin antibody V Oganesyan, L Peng, MM Damschroder, L Cheng, A Sadowska, ... Journal of Biological Chemistry 289 (43), 29874-29880, 2014 | 103 | 2014 |
Mouse model of hematogenous implant-related Staphylococcus aureus biofilm infection reveals therapeutic targets Y Wang, LI Cheng, DR Helfer, AG Ashbaugh, RJ Miller, AJ Tzomides, ... Proceedings of the National Academy of Sciences 114 (26), E5094-E5102, 2017 | 102 | 2017 |
S. aureus evades macrophage killing through NLRP3-dependent effects on mitochondrial trafficking TS Cohen, ML Boland, BB Boland, V Takahashi, A Tovchigrechko, Y Lee, ... Cell reports 22 (9), 2431-2441, 2018 | 98 | 2018 |
Staphylococcus aureus Alpha Toxin Suppresses Effective Innate and Adaptive Immune Responses in a Murine Dermonecrosis Model C Tkaczyk, MM Hamilton, V Datta, XP Yang, JJ Hilliard, GL Stephens, ... PLoS one 8 (10), e75103, 2013 | 98 | 2013 |
Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature A Thanabalasuriar, BGJ Surewaard, ME Willson, AS Neupane, CK Stover, ... The Journal of clinical investigation 127 (6), 2249-2261, 2017 | 93 | 2017 |
Candida albicans Augments Staphylococcus aureus Virulence by Engaging the Staphylococcal agr Quorum Sensing System OA Todd, PL Fidel Jr, JM Harro, JJ Hilliard, C Tkaczyk, BR Sellman, ... MBio 10 (3), 10.1128/mbio. 00910-19, 2019 | 92 | 2019 |
Generation of a membrane‐bound, oligomerized pre‐pore complex is necessary for pore formation by Clostridium septicum alpha toxin BR Sellman, BL Kagan, RK Tweten Molecular microbiology 23 (3), 551-558, 1997 | 90 | 1997 |