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MICHAEL A LAFLAMME
MICHAEL A LAFLAMME
University Health Network
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Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
MA Laflamme, KY Chen, AV Naumova, V Muskheli, JA Fugate, SK Dupras, ...
Nature biotechnology 25 (9), 1015-1024, 2007
27332007
Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts
JJH Chong, X Yang, CW Don, E Minami, YW Liu, JJ Weyers, ...
Nature 510 (7504), 273-277, 2014
16072014
Heart regeneration
MA Laflamme, CE Murry
Nature 473 (7347), 326-335, 2011
16002011
Regenerating the heart
MA Laflamme, CE Murry
Nature biotechnology 23 (7), 845-856, 2005
12792005
Biowire: a platform for maturation of human pluripotent stem cell–derived cardiomyocytes
SS Nunes, JW Miklas, J Liu, R Aschar-Sobbi, Y Xiao, B Zhang, J Jiang, ...
Nature methods 10 (8), 781-787, 2013
10962013
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies
G Wang, ML McCain, L Yang, A He, FS Pasqualini, A Agarwal, H Yuan, ...
Nature medicine 20 (6), 616-623, 2014
9412014
Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts
Y Shiba, S Fernandes, WZ Zhu, D Filice, V Muskheli, J Kim, NJ Palpant, ...
Nature 489 (7415), 322-325, 2012
9122012
Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells
SD Lundy, WZ Zhu, M Regnier, MA Laflamme
Stem cells and development 22 (14), 1991-2002, 2013
8992013
Transplantation of undifferentiated murine embryonic stem cells in the heart: teratoma formation and immune response
J Nussbaum, E Minami, MA Laflamme, JAI Virag, CB Ware, A Masino, ...
The FASEB Journal 21 (7), 1345-1357, 2007
8222007
Proangiogenic scaffolds as functional templates for cardiac tissue engineering
LR Madden, DJ Mortisen, EM Sussman, SK Dupras, JA Fugate, JL Cuy, ...
Proceedings of the National Academy of Sciences 107 (34), 15211-15216, 2010
8062010
Evidence for cardiomyocyte repopulation by extracardiac progenitors in transplanted human hearts
MA Laflamme, D Myerson, JE Saffitz, CE Murry
Circulation research 90 (6), 634-640, 2002
6012002
Formation of human myocardium in the rat heart from human embryonic stem cells
MA Laflamme, J Gold, C Xu, M Hassanipour, E Rosler, S Police, ...
The American journal of pathology 167 (3), 663-671, 2005
5982005
Let-7 family of microRNA is required for maturation and adult-like metabolism in stem cell-derived cardiomyocytes
KT Kuppusamy, DC Jones, H Sperber, A Madan, KA Fischer, ...
Proceedings of the National Academy of Sciences 112 (21), E2785-E2794, 2015
2942015
Human embryonic stem cell-derived cardiomyocytes regenerate the infarcted pig heart but induce ventricular tachyarrhythmias
R Romagnuolo, H Masoudpour, A Porta-Sánchez, B Qiang, J Barry, ...
Stem cell reports 12 (5), 967-981, 2019
2902019
Age‐dependent cardiomyopathy in mitochondrial mutator mice is attenuated by overexpression of catalase targeted to mitochondria
DF Dai, T Chen, J Wanagat, M Laflamme, DJ Marcinek, MJ Emond, ...
Aging cell 9 (4), 536-544, 2010
2832010
Neuregulin/ErbB signaling regulates cardiac subtype specification in differentiating human embryonic stem cells
WZ Zhu, Y Xie, KW Moyes, JD Gold, B Askari, MA Laflamme
Circulation research 107 (6), 776-786, 2010
2632010
Proliferation of cardiomyocytes derived from human embryonic stem cells is mediated via the IGF/PI 3-kinase/Akt signaling pathway
TC McDevitt, MA Laflamme, CE Murry
Journal of molecular and cellular cardiology 39 (6), 865-873, 2005
2582005
Cell-based therapy for myocardial ischemia and infarction: pathophysiological mechanisms
MA Laflamme, S Zbinden, SE Epstein, CE Murry
Annu. Rev. Pathol. Mech. Dis. 2 (1), 307-339, 2007
2222007
Extracardiac progenitor cells repopulate most major cell types in the transplanted human heart
E Minami, MA Laflamme, JE Saffitz, CE Murry
Circulation 112 (19), 2951-2958, 2005
1972005
Human embryonic stem cell-derived cardiomyocytes engraft but do not alter cardiac remodeling after chronic infarction in rats
S Fernandes, AV Naumova, WZ Zhu, MA Laflamme, J Gold, CE Murry
Journal of molecular and cellular cardiology 49 (6), 941-949, 2010
1952010
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