Toll-like receptor 4 imparts ligand-specific recognition of bacterial lipopolysaccharide E Lien, TK Means, H Heine, A Yoshimura, S Kusumoto, K Fukase, ... The Journal of clinical investigation 105 (4), 497-504, 2000 | 966 | 2000 |
LPS-induced cytokine production in human monocytes and macrophages M Rossol, H Heine, U Meusch, D Quandt, C Klein, MJ Sweet, ... Critical Reviews™ in Immunology 31 (5), 2011 | 785 | 2011 |
Bacterial endotoxin: chemical constitution, biological recognition, host response, and immunological detoxification ET Rietschel, H Brade, O Holst, L Brade, S Müller-Loennies, U Mamat, ... Pathology of septic shock, 39-81, 1996 | 683 | 1996 |
Role of the toll-like receptor 4 in neuroinflammation in Alzheimer’s disease S Walter, M Letiembre, Y Liu, H Heine, B Penke, W Hao, B Bode, ... Cellular Physiology and Biochemistry 20 (6), 947-956, 2007 | 652 | 2007 |
TLR2–promiscuous or specific? A critical re-evaluation of a receptor expressing apparent broad specificity U Zähringer, B Lindner, S Inamura, H Heine, C Alexander Immunobiology 213 (3-4), 205-224, 2008 | 474 | 2008 |
LPS receptor (CD14): a receptor for phagocytosis of Alzheimer's amyloid peptide Y Liu, S Walter, M Stagi, D Cherny, M Letiembre, W Schulz-Schaeffer, ... Brain 128 (8), 1778-1789, 2005 | 462 | 2005 |
The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation A Blumenthal, S Ehlers, J Lauber, J Buer, C Lange, T Goldmann, H Heine, ... Blood 108 (3), 965-973, 2006 | 457 | 2006 |
Molecular mechanisms of endotoxin activity J Schletter, H Heine, AJ Ulmer, ET Rietschel Archives of microbiology 164, 383-389, 1995 | 449 | 1995 |
Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling K Farhat, S Riekenberg, H Heine, J Debarry, R Lang, J Mages, ... Journal of Leucocyte Biology 83 (3), 692-701, 2008 | 402 | 2008 |
Molecular genetic analysis of an endotoxin nonresponder mutant cell line: a point mutation in a conserved region of MD-2 abolishes endotoxin-induced signaling AB Schromm, E Lien, P Henneke, JC Chow, A Yoshimura, H Heine, ... The Journal of experimental medicine 194 (1), 79-88, 2001 | 390 | 2001 |
Lipopolysaccharide and ceramide docking to CD14 provokes ligand‐specific receptor clustering in rafts A Pfeiffer, A Böttcher, E Orsó, M Kapinsky, P Nagy, A Bodnár, I Spreitzer, ... European journal of immunology 31 (11), 3153-3164, 2001 | 384 | 2001 |
Acinetobacter lwoffii and Lactococcus lactis strains isolated from farm cowsheds possess strong allergy-protective properties J Debarry, H Garn, A Hanuszkiewicz, N Dickgreber, N Blümer, ... Journal of Allergy and Clinical Immunology 119 (6), 1514-1521, 2007 | 340 | 2007 |
TLR1-and TLR6-independent recognition of bacterial lipopeptides U Buwitt-Beckmann, H Heine, KH Wiesmüller, G Jung, R Brock, S Akira, ... Journal of Biological Chemistry 281 (14), 9049-9057, 2006 | 328 | 2006 |
Cutting edge: cells that carry A null allele for toll-like receptor 2 are capable of responding to endotoxin H Heine, CJ Kirschning, E Lien, BG Monks, M Rothe, DT Golenbock The Journal of Immunology 162 (12), 6971-6975, 1999 | 318 | 1999 |
TLR4-mediated inflammatory activation of human coronary artery endothelial cells by LPS S Zeuke, AJ Ulmer, S Kusumoto, HA Katus, H Heine Cardiovascular research 56 (1), 126-134, 2002 | 316 | 2002 |
Zinc signals are essential for lipopolysaccharide-induced signal transduction in monocytes H Haase, JL Ober-Blöbaum, G Engelhardt, S Hebel, A Heit, H Heine, ... The Journal of Immunology 181 (9), 6491-6502, 2008 | 307 | 2008 |
Toll‐like receptor 6‐independent signaling by diacylated lipopeptides U Buwitt‐Beckmann, H Heine, KH Wiesmüller, G Jung, R Brock, S Akira, ... European journal of immunology 35 (1), 282-289, 2005 | 293 | 2005 |
Toll-like receptors and their function in innate and adaptive immunity H Heine, E Lien International archives of allergy and immunology 130 (3), 180-192, 2003 | 262 | 2003 |
The biology of endotoxin H Heine, ET Rietschel, AJ Ulmer Molecular biotechnology 19, 279-296, 2001 | 238 | 2001 |
Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis F Herster, Z Bittner, NK Archer, S Dickhöfer, D Eisel, T Eigenbrod, ... Nature communications 11 (1), 105, 2020 | 213 | 2020 |