Aberrant iron distribution via hepatocyte-stellate cell axis drives liver lipogenesis and fibrosis H Gao, Z Jin, G Bandyopadhyay, G Wang, D Zhang, KC e Rocha, X Liu, ... Cell metabolism 34 (8), 1201-1213. e5, 2022 | 111 | 2022 |
Cancer as robust intrinsic state shaped by evolution: a key issues review R Yuan, X Zhu, G Wang, P Ao Reports on Progress in Physics 80 (4), 042701, 2017 | 63 | 2017 |
An efficient combination immunotherapy for primary liver cancer by harmonized activation of innate and adaptive immunity in mice L Wen, B Xin, P Wu, CH Lin, C Peng, G Wang, J Lee, LF Lu, GS Feng Hepatology 69 (6), 2518-2532, 2019 | 60 | 2019 |
Shp2 deletion in hepatocytes suppresses hepatocarcinogenesis driven by oncogenic β-Catenin, PIK3CA and MET JJ Liu, Y Li, WS Chen, Y Liang, G Wang, M Zong, K Kaneko, R Xu, ... Journal of hepatology 69 (1), 79-88, 2018 | 51 | 2018 |
Potential landscape of high dimensional nonlinear stochastic dynamics with large noise Y Tang, R Yuan, G Wang, X Zhu, P Ao Scientific reports 7 (1), 15762, 2017 | 43 | 2017 |
Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes H Zhu, G Wang, KV Nguyen-Ngoc, D Kim, M Miller, G Goss, J Kovsky, ... Developmental Cell 58 (9), 727-743. e11, 2023 | 41 | 2023 |
Endogenous molecular network reveals two mechanisms of heterogeneity within gastric cancer X Zhu, B Liu, G Wang, P Ao Oncotarget 6 (15), 13607, 2015 | 40 | 2015 |
Quantitative implementation of the endogenous molecular–cellular network hypothesis in hepatocellular carcinoma G Wang, X Zhu, J Gu, P Ao Interface focus 4 (3), 20130064, 2014 | 39 | 2014 |
From Phage lambda to human cancer: endogenous molecular‐cellular network hypothesis G Wang, X Zhu, L Hood, P Ao Quantitative Biology 1 (1), 32-49, 2013 | 33 | 2013 |
Preventive inhibition of liver tumorigenesis by systemic activation of innate immune functions J Lee, R Liao, G Wang, BH Yang, X Luo, NM Varki, SJ Qiu, B Ren, W Fu, ... Cell reports 21 (7), 1870-1882, 2017 | 30 | 2017 |
Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes G Wang, J Chiou, C Zeng, M Miller, I Matta, JY Han, N Kadakia, ML Okino, ... Nature genetics 55 (6), 984-994, 2023 | 27 | 2023 |
Decoding early myelopoiesis from dynamics of core endogenous network H Su, G Wang, R Yuan, J Wang, Y Tang, P Ao, X Zhu Science China Life Sciences 60, 627-646, 2017 | 24 | 2017 |
Nutrient regulation of the islet epigenome controls adaptive insulin secretion M Wortham, F Liu, AR Harrington, JY Fleischman, M Wallace, F Mulas, ... The Journal of Clinical Investigation 133 (8), 2023 | 20 | 2023 |
Type 1 diabetes risk genes mediate pancreatic beta cell survival in response to proinflammatory cytokines P Benaglio, H Zhu, ML Okino, J Yan, R Elgamal, N Nariai, E Beebe, ... Cell Genomics 2 (12), 2022 | 19 | 2022 |
Key network approach reveals new insight into Alzheimer's disease JK Schluesener, X Zhu, HJ Schluesener, GW Wang, P Ao IET systems biology 8 (4), 169-175, 2014 | 16 | 2014 |
A tumorigenic index for quantitative analysis of liver cancer initiation and progression G Wang, X Luo, Y Liang, K Kaneko, H Li, XD Fu, GS Feng Proceedings of the National Academy of Sciences 116 (52), 26873-26880, 2019 | 12 | 2019 |
Concurrent disruption of the Ras/MAPK and NF-κB pathways induces circadian deregulation and hepatocarcinogenesis KL Hanley, Y Liang, G Wang, X Lin, M Yang, M Karin, W Fu, GS Feng Molecular Cancer Research 20 (3), 337-349, 2022 | 11 | 2022 |
RNA binding protein DDX5 restricts RORγt+ Treg suppressor function to promote intestine inflammation S Ma, Q Yang, N Chen, A Zheng, N Abbasi, G Wang, PR Patel, BS Cho, ... Science Advances 9 (5), eadd6165, 2023 | 10 | 2023 |
Endogenous molecular-cellular network cancer theory: A systems biology approach G Wang, R Yuan, X Zhu, P Ao Systems Biology, 215-245, 2018 | 10 | 2018 |
Endogenous network states predict gain or loss of functions for genetic mutations in hepatocellular carcinoma G Wang, H Su, H Yu, R Yuan, X Zhu, P Ao Journal of The Royal Society Interface 13 (115), 20151115, 2016 | 10 | 2016 |