Clinical and therapeutic relevance of cancer-associated fibroblasts Y Chen, KM McAndrews, R Kalluri Nature reviews Clinical oncology 18 (12), 792-804, 2021 | 746 | 2021 |
Generation and testing of clinical-grade exosomes for pancreatic cancer M Mendt, S Kamerkar, H Sugimoto, KM McAndrews, CC Wu, M Gagea, ... JCI insight 3 (8), 2018 | 725 | 2018 |
Mechanisms associated with biogenesis of exosomes in cancer KM McAndrews, R Kalluri Molecular cancer 18 (1), 52, 2019 | 379 | 2019 |
Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker FG Kugeratski, K Hodge, S Lilla, KM McAndrews, X Zhou, RF Hwang, ... Nature cell biology 23 (6), 631-641, 2021 | 375 | 2021 |
The role of extracellular vesicles in cancer R Kalluri, KM McAndrews Cell 186 (8), 1610-1626, 2023 | 259 | 2023 |
Epigenetic reprogramming of cancer-associated fibroblasts deregulates glucose metabolism and facilitates progression of breast cancer LM Becker, JT O’Connell, AP Vo, MP Cain, D Tampe, L Bizarro, ... Cell reports 31 (9), 2020 | 225 | 2020 |
Identification of functional heterogeneity of carcinoma-associated fibroblasts with distinct IL6-mediated therapy resistance in pancreatic cancer KM McAndrews, Y Chen, JK Darpolor, X Zheng, S Yang, JL Carstens, B Li, ... Cancer discovery 12 (6), 1580-1597, 2022 | 176 | 2022 |
Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer Y Chen, S Yang, J Tavormina, D Tampe, M Zeisberg, H Wang, ... Cancer cell 40 (8), 818-834. e9, 2022 | 164 | 2022 |
Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates DJ McGrail, J Dai, KM McAndrews, R Kalluri PloS one 15 (7), e0236619, 2020 | 162 | 2020 |
Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2 L El-Shennawy, AD Hoffmann, NK Dashzeveg, KM McAndrews, PJ Mehl, ... Nature Communications 13 (1), 405, 2022 | 152 | 2022 |
Heterogeneous antibodies against SARS-CoV-2 spike receptor binding domain and nucleocapsid with implications for COVID-19 immunity KM McAndrews, DP Dowlatshahi, J Dai, LM Becker, J Hensel, ... JCI insight 5 (18), 2020 | 147 | 2020 |
Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic KrasG12D in pancreatic cancer KM McAndrews, F Xiao, A Chronopoulos, VS LeBleu, FG Kugeratski, ... Life science alliance 4 (9), 2021 | 142 | 2021 |
Mesenchymal stem cells induce directional migration of invasive breast cancer cells through TGF-β KM McAndrews, DJ McGrail, N Ravikumar, MR Dawson Scientific reports 5 (1), 16941, 2015 | 104 | 2015 |
KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells KK Mahadevan, KM McAndrews, VS LeBleu, S Yang, H Lyu, B Li, ... Cancer Cell 41 (9), 1606-1620. e8, 2023 | 98 | 2023 |
Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta Y Chen, S Yang, S Lovisa, CG Ambrose, KM McAndrews, H Sugimoto, ... Nature communications 12 (1), 7199, 2021 | 86 | 2021 |
Protection against SARS-CoV-2 by BCG vaccination is not supported by epidemiological analyses J Hensel, KM McAndrews, DJ McGrail, DP Dowlatshahi, VS LeBleu, ... Scientific reports 10 (1), 18377, 2020 | 83 | 2020 |
Cysteine (C)-xC receptor 4 undergoes transportin 1-dependent nuclear localization and remains functional at the nucleus of metastatic prostate cancer cells AS Don-Salu-Hewage, SY Chan, KM McAndrews, MA Chetram, ... PloS one 8 (2), e57194, 2013 | 74 | 2013 |
Therapeutic targeting of STAT3 employing small interference RNAs and antisense oligonucleotides embedded exosomes in liver fibrosis M Tang, Y Chen, B Li, H Sugimoto, S Yang, C Yang, VS LeBleu, ... FASEB journal: official publication of the Federation of American Societies …, 2021 | 72 | 2021 |
Stabilized epithelial phenotype of cancer cells in primary tumors leads to increased colonization of liver metastasis in pancreatic cancer JL Carstens, S Yang, PC De Sampaio, X Zheng, S Barua, KM McAndrews, ... Cell reports 35 (2), 2021 | 67 | 2021 |
Effective delivery of STING agonist using exosomes suppresses tumor growth and enhances antitumor immunity KM McAndrews, SPY Che, VS LeBleu, R Kalluri Journal of Biological Chemistry 296, 2021 | 64 | 2021 |