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Kathleen M McAndrews
Kathleen M McAndrews
Assistant Professor, MD Anderson Cancer Center
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Clinical and therapeutic relevance of cancer-associated fibroblasts
Y Chen, KM McAndrews, R Kalluri
Nature reviews Clinical oncology 18 (12), 792-804, 2021
7462021
Generation and testing of clinical-grade exosomes for pancreatic cancer
M Mendt, S Kamerkar, H Sugimoto, KM McAndrews, CC Wu, M Gagea, ...
JCI insight 3 (8), 2018
7252018
Mechanisms associated with biogenesis of exosomes in cancer
KM McAndrews, R Kalluri
Molecular cancer 18 (1), 52, 2019
3792019
Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker
FG Kugeratski, K Hodge, S Lilla, KM McAndrews, X Zhou, RF Hwang, ...
Nature cell biology 23 (6), 631-641, 2021
3752021
The role of extracellular vesicles in cancer
R Kalluri, KM McAndrews
Cell 186 (8), 1610-1626, 2023
2592023
Epigenetic reprogramming of cancer-associated fibroblasts deregulates glucose metabolism and facilitates progression of breast cancer
LM Becker, JT O’Connell, AP Vo, MP Cain, D Tampe, L Bizarro, ...
Cell reports 31 (9), 2020
2252020
Identification of functional heterogeneity of carcinoma-associated fibroblasts with distinct IL6-mediated therapy resistance in pancreatic cancer
KM McAndrews, Y Chen, JK Darpolor, X Zheng, S Yang, JL Carstens, B Li, ...
Cancer discovery 12 (6), 1580-1597, 2022
1762022
Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer
Y Chen, S Yang, J Tavormina, D Tampe, M Zeisberg, H Wang, ...
Cancer cell 40 (8), 818-834. e9, 2022
1642022
Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates
DJ McGrail, J Dai, KM McAndrews, R Kalluri
PloS one 15 (7), e0236619, 2020
1622020
Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2
L El-Shennawy, AD Hoffmann, NK Dashzeveg, KM McAndrews, PJ Mehl, ...
Nature Communications 13 (1), 405, 2022
1522022
Heterogeneous antibodies against SARS-CoV-2 spike receptor binding domain and nucleocapsid with implications for COVID-19 immunity
KM McAndrews, DP Dowlatshahi, J Dai, LM Becker, J Hensel, ...
JCI insight 5 (18), 2020
1472020
Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic KrasG12D in pancreatic cancer
KM McAndrews, F Xiao, A Chronopoulos, VS LeBleu, FG Kugeratski, ...
Life science alliance 4 (9), 2021
1422021
Mesenchymal stem cells induce directional migration of invasive breast cancer cells through TGF-β
KM McAndrews, DJ McGrail, N Ravikumar, MR Dawson
Scientific reports 5 (1), 16941, 2015
1042015
KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T cells
KK Mahadevan, KM McAndrews, VS LeBleu, S Yang, H Lyu, B Li, ...
Cancer Cell 41 (9), 1606-1620. e8, 2023
982023
Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta
Y Chen, S Yang, S Lovisa, CG Ambrose, KM McAndrews, H Sugimoto, ...
Nature communications 12 (1), 7199, 2021
862021
Protection against SARS-CoV-2 by BCG vaccination is not supported by epidemiological analyses
J Hensel, KM McAndrews, DJ McGrail, DP Dowlatshahi, VS LeBleu, ...
Scientific reports 10 (1), 18377, 2020
832020
Cysteine (C)-xC receptor 4 undergoes transportin 1-dependent nuclear localization and remains functional at the nucleus of metastatic prostate cancer cells
AS Don-Salu-Hewage, SY Chan, KM McAndrews, MA Chetram, ...
PloS one 8 (2), e57194, 2013
742013
Therapeutic targeting of STAT3 employing small interference RNAs and antisense oligonucleotides embedded exosomes in liver fibrosis
M Tang, Y Chen, B Li, H Sugimoto, S Yang, C Yang, VS LeBleu, ...
FASEB journal: official publication of the Federation of American Societies …, 2021
722021
Stabilized epithelial phenotype of cancer cells in primary tumors leads to increased colonization of liver metastasis in pancreatic cancer
JL Carstens, S Yang, PC De Sampaio, X Zheng, S Barua, KM McAndrews, ...
Cell reports 35 (2), 2021
672021
Effective delivery of STING agonist using exosomes suppresses tumor growth and enhances antitumor immunity
KM McAndrews, SPY Che, VS LeBleu, R Kalluri
Journal of Biological Chemistry 296, 2021
642021
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