Molecular mechanisms of cell death in neurological diseases D Moujalled, A Strasser, JR Liddell Cell Death & Differentiation 28 (7), 2029-2044, 2021 | 492 | 2021 |
Targeting Nrf2 to suppress ferroptosis and mitochondrial dysfunction in neurodegeneration M Abdalkader, R Lampinen, KM Kanninen, TM Malm, JR Liddell Frontiers in Neuroscience 12, 466, 2018 | 398 | 2018 |
Endogenous TDP-43 localized to stress granules can subsequently form protein aggregates SJ Parker, J Meyerowitz, JL James, JR Liddell, PJ Crouch, KM Kanninen, ... Neurochemistry international 60 (4), 415-424, 2012 | 197 | 2012 |
Oral treatment with CuII (atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis BR Roberts, NKH Lim, EJ McAllum, PS Donnelly, DJ Hare, PA Doble, ... Journal of Neuroscience 34 (23), 8021-8031, 2014 | 188 | 2014 |
Are astrocytes the predominant cell type for activation of Nrf2 in aging and neurodegeneration? JR Liddell Antioxidants 6 (3), 65, 2017 | 177 | 2017 |
C-Jun N-terminal kinase controls TDP-43 accumulation in stress granules induced by oxidative stress J Meyerowitz, SJ Parker, LJ Vella, DCH Ng, KA Price, JR Liddell, ... Molecular neurodegeneration 6, 1-22, 2011 | 148 | 2011 |
An impaired mitochondrial electron transport chain increases retention of the hypoxia imaging agent diacetylbis (4-methylthiosemicarbazonato) copperII PS Donnelly, JR Liddell, SC Lim, BM Paterson, MA Cater, MS Savva, ... Proceedings of the National Academy of Sciences 109 (1), 47-52, 2012 | 124 | 2012 |
Glutathione peroxidase 1 and glutathione are required to protect mouse astrocytes from iron‐mediated hydrogen peroxide toxicity JR Liddell, HH Hoepken, PJ Crack, SR Robinson, R Dringen Journal of neuroscience research 84 (3), 578-586, 2006 | 95 | 2006 |
TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway D Moujalled, A Grubman, K Acevedo, S Yang, YD Ke, DM Moujalled, ... Human Molecular Genetics 26 (9), 1732-1746, 2017 | 89 | 2017 |
Therapeutic effects of CuII (atsm) in the SOD1-G37R mouse model of amyotrophic lateral sclerosis EJ McAllum, NKH Lim, JL Hickey, BM Paterson, PS Donnelly, QX Li, ... Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration 14 (7-8), 586-590, 2013 | 89 | 2013 |
Nexus between mitochondrial function, iron, copper and glutathione in Parkinson's disease JR Liddell, AR White Neurochemistry international 117, 126-138, 2018 | 72 | 2018 |
Kinase inhibitor screening identifies cyclin-dependent kinases and glycogen synthase kinase 3 as potential modulators of TDP-43 cytosolic accumulation during cell stress D Moujalled, JL James, SJ Parker, GE Lidgerwood, C Duncan, ... PloS one 8 (6), e67433, 2013 | 70 | 2013 |
Glutathione peroxidase 1 and a high cellular glutathione concentration are essential for effective organic hydroperoxide detoxification in astrocytes JR Liddell, R Dringen, PJ Crack, SR Robinson Glia 54 (8), 873-879, 2006 | 62 | 2006 |
Circumventing the Crabtree Effect: A method to induce lactate consumption and increase oxidative phosphorylation in cell culture AI Mot, JR Liddell, AR White, PJ Crouch The International Journal of Biochemistry & Cell Biology 79, 128-138, 2016 | 61 | 2016 |
Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass … DJ Hare, A Grubman, TM Ryan, A Lothian, JR Liddell, R Grimm, ... Metallomics 5 (12), 1656-1662, 2013 | 58 | 2013 |
Neuron-astrocyte transmitophagy is altered in Alzheimer's disease R Lampinen, I Belaya, L Saveleva, JR Liddell, D Rait, MT Huuskonen, ... Neurobiology of Disease 170, 105753, 2022 | 57 | 2022 |
Phosphorylation of hnRNP K by cyclin-dependent kinase 2 controls cytosolic accumulation of TDP-43 D Moujalled, JL James, S Yang, K Zhang, C Duncan, DM Moujalled, ... Human molecular genetics 24 (6), 1655-1669, 2015 | 56 | 2015 |
The challenges of using a copper fluorescent sensor (CS1) to track intracellular distributions of copper in neuronal and glial cells KA Price, JL Hickey, Z Xiao, AG Wedd, SA James, JR Liddell, PJ Crouch, ... Chemical Science 3 (9), 2748-2759, 2012 | 56 | 2012 |
Inhibition of TDP-43 Accumulation by Bis(thiosemicarbazonato)-Copper Complexes SJ Parker, J Meyerowitz, JL James, JR Liddell, T Nonaka, M Hasegawa, ... Public Library of Science 7 (8), e42277, 2012 | 55 | 2012 |
Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain NKH Lim, LW Hung, TY Pang, CA Mclean, JR Liddell, JB Hilton, QX Li, ... Human Molecular Genetics 23 (15), 4051-4063, 2014 | 52 | 2014 |