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Javad Nazarian
Javad Nazarian
Associate Professor, Integrative Systems Biology, George Washington University, Head, DMG Research
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Functionally defined therapeutic targets in diffuse intrinsic pontine glioma
CS Grasso, Y Tang, N Truffaux, NE Berlow, L Liu, MA Debily, MJ Quist, ...
Nature medicine 21 (6), 555-559, 2015
6782015
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations
P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ...
Nature genetics 46 (5), 451-456, 2014
6652014
Clinical, radiologic, pathologic, and molecular characteristics of long-term survivors of diffuse intrinsic pontine glioma (DIPG): a collaborative report from the International …
LM Hoffman, SEM Veldhuijzen van Zanten, N Colditz, J Baugh, B Chaney, ...
Journal of clinical oncology 36 (19), 1963-1972, 2018
3902018
Integrated proteogenomic characterization across major histological types of pediatric brain cancer
F Petralia, N Tignor, B Reva, M Koptyra, S Chowdhury, D Rykunov, A Krek, ...
Cell 183 (7), 1962-1985. e31, 2020
2612020
Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma
H Nikbakht, E Panditharatna, LG Mikael, R Li, T Gayden, M Osmond, ...
Nature communications 7 (1), 11185, 2016
2572016
Preclinical evaluation of radiation and perifosine in a genetically and histologically accurate model of brainstem glioma
OJ Becher, D Hambardzumyan, TR Walker, K Helmy, J Nazarian, ...
Cancer research 70 (6), 2548-2557, 2010
1942010
Asynchronous remodeling is a driver of failed regeneration in Duchenne muscular dystrophy
S Dadgar, Z Wang, H Johnston, A Kesari, K Nagaraju, YW Chen, DA Hill, ...
Journal of Cell Biology 207 (1), 139-158, 2014
1842014
Clinically relevant and minimally invasive tumor surveillance of pediatric diffuse midline gliomas using patient-derived liquid biopsy
E Panditharatna, LB Kilburn, MS Aboian, M Kambhampati, ...
Clinical Cancer Research 24 (23), 5850-5859, 2018
1702018
Histone variant and cell context determine H3K27M reprogramming of the enhancer landscape and oncogenic state
S Nagaraja, MA Quezada, SM Gillespie, M Arzt, JJ Lennon, PJ Woo, ...
Molecular cell 76 (6), 965-980. e12, 2019
1522019
Advances in the proteomic investigation of the cell secretome
KJ Brown, CA Formolo, H Seol, RL Marathi, S Duguez, E An, D Pillai, ...
Expert review of proteomics 9 (3), 337-345, 2012
1312012
Comparative multidimensional molecular analyses of pediatric diffuse intrinsic pontine glioma reveals distinct molecular subtypes
AM Saratsis, M Kambhampati, K Snyder, S Yadavilli, JM Devaney, ...
Acta neuropathologica 127, 881-895, 2014
1172014
A pilot precision medicine trial for children with diffuse intrinsic pontine glioma—PNOC003: A report from the Pacific Pediatric Neuro‐Oncology Consortium
S Mueller, P Jain, WS Liang, L Kilburn, C Kline, N Gupta, E Panditharatna, ...
International journal of cancer 145 (7), 1889-1901, 2019
1162019
ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis
CM Hoeman, FJ Cordero, G Hu, K Misuraca, MM Romero, HJ Cardona, ...
Nature communications 10 (1), 1023, 2019
1122019
Direct analysis of lipids and small metabolites in mouse brain tissue by AP IR-MALDI and reactive LAESI mass spectrometry
B Shrestha, P Nemes, J Nazarian, Y Hathout, EP Hoffman, A Vertes
Analyst 135 (4), 751-758, 2010
1092010
Mass cytometry detects H3. 3K27M-specific vaccine responses in diffuse midline glioma
S Mueller, JM Taitt, JE Villanueva-Meyer, ER Bonner, T Nejo, RR Lulla, ...
The Journal of clinical investigation 130 (12), 2022
1062022
Molecular imaging of biological samples on nanophotonic laser desorption ionization platforms
SA Stopka, C Rong, AR Korte, S Yadavilli, J Nazarian, TT Razunguzwa, ...
Angewandte Chemie International Edition 55 (14), 4482-4486, 2016
1062016
Insights into pediatric diffuse intrinsic pontine glioma through proteomic analysis of cerebrospinal fluid
AM Saratsis, S Yadavilli, S Magge, BR Rood, J Perez, DA Hill, E Hwang, ...
Neuro-oncology 14 (5), 547-560, 2012
922012
Clinical outcomes and patient-matched molecular composition of relapsed medulloblastoma
R Kumar, KS Smith, M Deng, C Terhune, GW Robinson, BA Orr, APY Liu, ...
Journal of Clinical Oncology 39 (7), 807-821, 2021
842021
PPM1D mutations silence NAPRT gene expression and confer NAMPT inhibitor sensitivity in glioma
NR Fons, RK Sundaram, GA Breuer, S Peng, RL McLean, AN Kalathil, ...
Nature communications 10 (1), 3790, 2019
832019
Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways
S Venneti, AR Kawakibi, S Ji, SM Waszak, SR Sweha, M Mota, M Pun, ...
Cancer discovery 13 (11), 2370-2393, 2023
812023
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