| The transcription factor STAT-1 couples macrophage synthesis of 25-hydroxycholesterol to the interferon antiviral response M Blanc, WY Hsieh, KA Robertson, KA Kropp, T Forster, G Shui, P Lacaze, ... Immunity 38 (1), 106-118, 2013 | 427 | 2013 |
| Stroke genetics informs drug discovery and risk prediction across ancestries A Mishra, R Malik, T Hachiya, T Jürgenson, S Namba, DC Posner, ... Nature 611 (7934), 115-123, 2022 | 341 | 2022 |
| Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis M Blanc, WY Hsieh, KA Robertson, S Watterson, G Shui, P Lacaze, ... PLoS biology 9 (3), e1000598, 2011 | 322 | 2011 |
| Consolidation of the cancer genome into domains of repressive chromatin by long-range epigenetic silencing (LRES) reduces transcriptional plasticity MW Coolen, C Stirzaker, JZ Song, AL Statham, Z Kassir, CS Moreno, ... Nature cell biology 12 (3), 235-246, 2010 | 218 | 2010 |
| Identification of a human neonatal immune-metabolic network associated with bacterial infection CL Smith, P Dickinson, T Forster, M Craigon, A Ross, MR Khondoker, ... Nature communications 5 (1), 4649, 2014 | 155 | 2014 |
| Population genomic screening of all young adults in a health-care system: a cost-effectiveness analysis L Zhang, Y Bao, M Riaz, J Tiller, D Liew, X Zhuang, DJ Amor, A Huq, ... Genetics in Medicine 21 (9), 1958-1968, 2019 | 100 | 2019 |
| Integrated guidance for enhancing the care of familial hypercholesterolaemia in Australia GF Watts, DR Sullivan, DL Hare, KM Kostner, AE Horton, DA Bell, T Brett, ... Heart, Lung and Circulation 30 (3), 324-349, 2021 | 97 | 2021 |
| Phenotypic heterogeneity in dementia: a challenge for epidemiology and biomarker studies J Ryan, P Fransquet, J Wrigglesworth, P Lacaze Frontiers in public health 6, 181, 2018 | 91 | 2018 |
| A logic-based diagram of signalling pathways central to macrophage activation S Raza, KA Robertson, PA Lacaze, D Page, AJ Enright, P Ghazal, ... BMC systems biology 2, 1-15, 2008 | 87 | 2008 |
| Blood DNA methylation as a potential biomarker of dementia: a systematic review PD Fransquet, P Lacaze, R Saffery, J McNeil, R Woods, J Ryan Alzheimer's & Dementia 14 (1), 81-103, 2018 | 86 | 2018 |
| Aspirin for primary prevention of cardiovascular events in relation to lipoprotein (a) genotypes P Lacaze, A Bakshi, M Riaz, G Polekhina, A Owen, HS Bhatia, ... Journal of the American College of Cardiology 80 (14), 1287-1298, 2022 | 85 | 2022 |
| The Medical Genome Reference Bank contains whole genome and phenotype data of 2570 healthy elderly M Pinese, P Lacaze, EM Rath, A Stone, MJ Brion, A Ameur, S Nagpal, ... Nature communications 11 (1), 435, 2020 | 72 | 2020 |
| ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype S Junankar, LA Baker, DL Roden, R Nair, B Elsworth, D Gallego-Ortega, ... Nature communications 6 (1), 6548, 2015 | 66 | 2015 |
| Public involvement in global genomics research: a scoping review JS Nunn, J Tiller, P Fransquet, P Lacaze Frontiers in public health 7, 79, 2019 | 54 | 2019 |
| Construction of a large scale integrated map of macrophage pathogen recognition and effector systems S Raza, N McDerment, PA Lacaze, K Robertson, S Watterson, Y Chen, ... BMC systems biology 4, 1-18, 2010 | 52 | 2010 |
| Genetic discrimination by Australian insurance companies: a survey of consumer experiences J Tiller, S Morris, T Rice, K Barter, M Riaz, L Keogh, MB Delatycki, ... European Journal of Human Genetics 28 (1), 108-113, 2020 | 51 | 2020 |
| Rare disease registries: a call to action P Lacaze, N Millis, M Fookes, Y Zurynski, A Jaffe, M Bellgard, I Winship, ... Internal medicine journal 47 (9), 1075-1079, 2017 | 51 | 2017 |
| Reversible inhibition of murine cytomegalovirus replication by gamma interferon (IFN-γ) in primary macrophages involves a primed type I IFN-signaling subnetwork for full … KA Kropp, KA Robertson, G Sing, S Rodriguez-Martin, M Blanc, P Lacaze, ... Journal of virology 85 (19), 10286-10299, 2011 | 48 | 2011 |
| Population genomic screening of young adults for familial hypercholesterolaemia: a cost-effectiveness analysis C Marquina, P Lacaze, J Tiller, M Riaz, AC Sturm, MR Nelson, ... European Heart Journal 43 (34), 3243-3254, 2022 | 40 | 2022 |
| The Medical Genome Reference Bank: a whole-genome data resource of 4000 healthy elderly individuals. Rationale and cohort design P Lacaze, M Pinese, W Kaplan, A Stone, MJ Brion, RL Woods, ... European Journal of Human Genetics 27 (2), 308-316, 2019 | 40 | 2019 |