Receptors: models for binding, trafficking, and signaling DA Lauffenburger, JJ Linderman Oxford University Press, USA, 1996 | 1478 | 1996 |
Dynamic balance of pro‐and anti‐inflammatory signals controls disease and limits pathology JM Cicchese, S Evans, C Hult, LR Joslyn, T Wessler, JA Millar, S Marino, ... Immunological reviews 285 (1), 147-167, 2018 | 300 | 2018 |
Nanoscale adhesion ligand organization regulates osteoblast proliferation and differentiation KY Lee, E Alsberg, S Hsiong, W Comisar, J Linderman, R Ziff, D Mooney Nano letters 4 (8), 1501-1506, 2004 | 290 | 2004 |
Quantitative measurement and control of oxygen levels in microfluidic poly (dimethylsiloxane) bioreactors during cell culture G Mehta, K Mehta, D Sud, JW Song, T Bersano-Begey, N Futai, YS Heo, ... Biomedical microdevices 9, 123-134, 2007 | 271 | 2007 |
Macrophage polarization drives granuloma outcome during Mycobacterium tuberculosis infection S Marino, NA Cilfone, JT Mattila, JJ Linderman, JAL Flynn, DE Kirschner Infection and immunity 83 (1), 324-338, 2015 | 221 | 2015 |
Multiscale computational modeling reveals a critical role for TNF-α receptor 1 dynamics in tuberculosis granuloma formation M Fallahi-Sichani, M El-Kebir, S Marino, DE Kirschner, JJ Linderman The Journal of Immunology 186 (6), 3472-3483, 2011 | 200 | 2011 |
A spatial focusing model for G protein signals: regulator of G protein signaling (RGS) protein-mediated kinetic scaffolding H Zhong, SM Wade, PJ Woolf, JJ Linderman, JR Traynor, RR Neubig Journal of Biological Chemistry 278 (9), 7278-7284, 2003 | 166 | 2003 |
Engineering RGD nanopatterned hydrogels to control preosteoblast behavior: a combined computational and experimental approach WA Comisar, NH Kazmers, DJ Mooney, JJ Linderman Biomaterials 28 (30), 4409-4417, 2007 | 163 | 2007 |
Hard top soft bottom microfluidic devices for cell culture and chemical analysis G Mehta, J Lee, W Cha, YC Tung, JJ Linderman, S Takayama Analytical chemistry 81 (10), 3714-3722, 2009 | 138 | 2009 |
An adaptive, Cartesian, front-tracking method for the motion, deformation and adhesion of circulating cells G Agresar, JJ Linderman, G Tryggvason, KG Powell Journal of Computational Physics 143 (2), 346-380, 1998 | 135 | 1998 |
Multi-scale modeling predicts a balance of tumor necrosis factor-α and interleukin-10 controls the granuloma environment during Mycobacterium tuberculosis infection NA Cilfone, CR Perry, DE Kirschner, JJ Linderman PloS one 8 (7), e68680, 2013 | 132 | 2013 |
Differential risk of tuberculosis reactivation among anti-TNF therapies is due to drug binding kinetics and permeability M Fallahi-Sichani, JAL Flynn, JJ Linderman, DE Kirschner The Journal of Immunology 188 (7), 3169-3178, 2012 | 123 | 2012 |
Optical imaging in microfluidic bioreactors enables oxygen monitoring for continuous cell culture D Sud, G Mehta, K Mehta, J Linderman, S Takayama, MA Mycek Journal of biomedical optics 11 (5), 050504-050504-3, 2006 | 121 | 2006 |
NF-κB signaling dynamics play a key role in infection control in tuberculosis M Fallahi-Sichani, DE Kirschner, JJ Linderman Frontiers in physiology 3, 170, 2012 | 119 | 2012 |
Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space EK Makowski, PC Kinnunen, J Huang, L Wu, MD Smith, T Wang, ... Nature communications 13 (1), 3788, 2022 | 115 | 2022 |
Multiple mechanisms allow Mycobacterium tuberculosis to continuously inhibit MHC class II-mediated antigen presentation by macrophages ST Chang, JJ Linderman, DE Kirschner Proceedings of the National Academy of Sciences 102 (12), 4530-4535, 2005 | 115 | 2005 |
Strategies for efficient numerical implementation of hybrid multi-scale agent-based models to describe biological systems NA Cilfone, DE Kirschner, JJ Linderman Cellular and molecular bioengineering 8, 119-136, 2015 | 114 | 2015 |
Push–pull perfusion sampling with segmented flow for high temporal and spatial resolution in vivo chemical monitoring TR Slaney, J Nie, ND Hershey, PK Thwar, J Linderman, MA Burns, ... Analytical chemistry 83 (13), 5207-5213, 2011 | 110 | 2011 |
Improved tumor penetration and single-cell targeting of antibody–drug conjugates increases anticancer efficacy and host survival C Cilliers, B Menezes, I Nessler, J Linderman, GM Thurber Cancer research 78 (3), 758-768, 2018 | 104 | 2018 |
Lipid raft-mediated regulation of G-protein coupled receptor signaling by ligands which influence receptor dimerization: a computational study M Fallahi-Sichani, JJ Linderman PloS one 4 (8), e6604, 2009 | 104 | 2009 |