| Comprehensive computational design of ordered peptide macrocycles P Hosseinzadeh, G Bhardwaj, VK Mulligan, MD Shortridge, TW Craven, ... Science 358 (6369), 1461-1466, 2017 | 201 | 2017 |
| Accurate de novo design of membrane-traversing macrocycles G Bhardwaj, J O’Connor, S Rettie, YH Huang, TA Ramelot, VK Mulligan, ... Cell 185 (19), 3520-3532. e26, 2022 | 106 | 2022 |
| Design of Peptoid-peptide Macrocycles to Inhibit the β-catenin TCF Interaction in Prostate Cancer JA Schneider, TW Craven, AC Kasper, C Yun, M Haugbro, EM Briggs, ... Nature communications 9 (1), 4396, 2018 | 92 | 2018 |
| Adding diverse noncanonical backbones to rosetta: enabling peptidomimetic design K Drew, PD Renfrew, TW Craven, GL Butterfoss, FC Chou, S Lyskov, ... PLoS One 8 (7), e67051, 2013 | 79 | 2013 |
| The sulfur-linked analogue of O-GlcNAc (S-GlcNAc) is an enzymatically stable and reasonable structural surrogate for O-GlcNAc at the peptide and protein levels CA De Leon, PM Levine, TW Craven, MR Pratt Biochemistry 56 (27), 3507-3517, 2017 | 74 | 2017 |
| O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity AT Balana, PM Levine, TW Craven, S Mukherjee, NJ Pedowitz, SP Moon, ... Nature chemistry 13 (5), 441-450, 2021 | 71 | 2021 |
| A rotamer library to enable modeling and design of peptoid foldamers PD Renfrew, TW Craven, GL Butterfoss, K Kirshenbaum, R Bonneau Journal of the American Chemical Society 136 (24), 8772-8782, 2014 | 65 | 2014 |
| Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites P Hosseinzadeh, PR Watson, TW Craven, X Li, S Rettie, F Pardo-Avila, ... Nature Communications 12 (1), 3384, 2021 | 62 | 2021 |
| Computationally designed peptide macrocycle inhibitors of New Delhi metallo-β-lactamase 1 VK Mulligan, S Workman, T Sun, S Rettie, X Li, LJ Worrall, TW Craven, ... Proceedings of the National Academy of Sciences 118 (12), e2012800118, 2021 | 58 | 2021 |
| A miniature protein stabilized by a cation− π interaction network TW Craven, MK Cho, NJ Traaseth, R Bonneau, K Kirshenbaum Journal of the American Chemical Society 138 (5), 1543-1550, 2016 | 57 | 2016 |
| Semisynthesis of peptoid–protein hybrids by chemical ligation at serine PM Levine, TW Craven, R Bonneau, K Kirshenbaum Organic letters 16 (2), 512-515, 2014 | 47 | 2014 |
| De novo carborane-containing macrocyclic peptides targeting human epidermal growth factor receptor Y Yin, N Ochi, TW Craven, D Baker, N Takigawa, H Suga Journal of the American Chemical Society 141 (49), 19193-19197, 2019 | 46 | 2019 |
| Cyclic Peptide Screening Methods for Preclinical Drug Discovery: Miniperspective X Li, TW Craven, PM Levine Journal of Medicinal Chemistry 65 (18), 11913-11926, 2022 | 42 | 2022 |
| Intrinsic bioconjugation for site-specific protein PEGylation at N-terminal serine PM Levine, TW Craven, R Bonneau, K Kirshenbaum Chemical communications 50 (52), 6909-6912, 2014 | 36 | 2014 |
| Computational design of mixed chirality peptide macrocycles with internal symmetry VK Mulligan, CS Kang, MR Sawaya, S Rettie, X Li, I Antselovich, ... Protein Science 29 (12), 2433-2445, 2020 | 27 | 2020 |
| Chemoselective fragment condensation between peptide and peptidomimetic oligomers PM Levine, TW Craven, R Bonneau, K Kirshenbaum Organic & Biomolecular Chemistry 11 (25), 4142-4146, 2013 | 22 | 2013 |
| Rotamer libraries for the high-resolution design of β-amino acid foldamers AM Watkins, TW Craven, PD Renfrew, PS Arora, R Bonneau Structure 25 (11), 1771-1780. e3, 2017 | 19 | 2017 |
| Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor E Muratspahić, K Deibler, J Han, N Tomašević, KB Jadhav, AL Olivé-Marti, ... Nature communications 14 (1), 8064, 2023 | 16 | 2023 |
| Isolating conformers to assess dynamics of peptidic catalysts using computationally designed macrocyclic peptides EA Stone, P Hosseinzadeh, TW Craven, MJ Robertson, Y Han, SY Hsieh, ... ACS catalysis 11 (8), 4395-4400, 2021 | 16 | 2021 |
| PPII Helical Peptidomimetics Templated by Cation–π Interactions TW Craven, R Bonneau, K Kirshenbaum ChemBioChem 17 (19), 1824-1828, 2016 | 11 | 2016 |