| Chemistry and pharmacology of analgesic indole alkaloids from the rubiaceous plant, Mitragyna speciosa H Takayama Chemical and Pharmaceutical Bulletin 52 (8), 916-928, 2004 | 472 | 2004 |
| Comprehensive Flavonol Profiling and Transcriptome Coexpression Analysis Leading to Decoding Gene–Metabolite Correlations in Arabidopsis K Yonekura-Sakakibara, T Tohge, F Matsuda, R Nakabayashi, ... The Plant Cell 20 (8), 2160-2176, 2008 | 433 | 2008 |
| Pteropodine and isopteropodine positively modulate the function of rat muscarinic M1 and 5-HT2 receptors expressed in Xenopus oocyte TH Kang, K Matsumoto, M Tohda, Y Murakami, H Takayama, M Kitajima, ... European journal of pharmacology 444 (1-2), 39-45, 2002 | 398 | 2002 |
| Selenosugars are key and urinary metabolites for selenium excretion within the required to low-toxic range Y Kobayashi, Y Ogra, K Ishiwata, H Takayama, N Aimi, KT Suzuki Proceedings of the National Academy of Sciences 99 (25), 15932-15936, 2002 | 375 | 2002 |
| Studies on the synthesis and opioid agonistic activities of mitragynine-related indole alkaloids: discovery of opioid agonists structurally different from other opioid ligands H Takayama, H Ishikawa, M Kurihara, M Kitajima, N Aimi, D Ponglux, ... Journal of medicinal chemistry 45 (9), 1949-1956, 2002 | 315 | 2002 |
| Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from the Thai medicinal herb Mitragyna speciosa K Matsumoto, S Horie, H Ishikawa, H Takayama, N Aimi, D Ponglux, ... Life sciences 74 (17), 2143-2155, 2004 | 292 | 2004 |
| Central antinociceptive effects of mitragynine in mice: contribution of descending noradrenergic and serotonergic systems K Matsumoto, M Mizowaki, T Suchitra, Y Murakami, H Takayama, S Sakai, ... European journal of pharmacology 317 (1), 75-81, 1996 | 243 | 1996 |
| Rhynchophylline and isorhynchophylline inhibit NMDA receptors expressed in Xenopus oocytes TH Kang, Y Murakami, K Matsumoto, H Takayama, M Kitajima, N Aimi, ... European journal of pharmacology 455 (1), 27-34, 2002 | 197 | 2002 |
| Antinociceptive action of mitragynine in mice: evidence for the involvement of supraspinal opioid receptors K Matsumoto, M Mizowaki, T Suchitra, H Takayama, S Sakai, N Aimi, ... Life sciences 59 (14), 1149-1155, 1996 | 194 | 1996 |
| A new indole alkaloid, 7 α-hydroxy-7H-mitragynine, from Mitragyna speciosa in Thailand D Ponglux, S Wongseripipatana, H Takayama, M Kikuchi, M Kurihara, ... Planta medica 60 (06), 580-581, 1994 | 189 | 1994 |
| Characterization of a recently evolved flavonol-phenylacyltransferase gene provides signatures of natural light selection in Brassicaceae T Tohge, R Wendenburg, H Ishihara, R Nakabayashi, M Watanabe, ... Nature Communications 7 (1), 12399, 2016 | 185 | 2016 |
| Feasible production of camptothecin by hairy root culture of Ophiorrhiza pumila K Saito, H Sudo, M Yamazaki, M Koseki-Nakamura, M Kitajima, ... Plant Cell Reports 20, 267-271, 2001 | 178 | 2001 |
| Two new tryptamine-derived alkaloids from Chimonanthus praecox f. concolor M Kitajima, I Mori, K Arai, N Kogure, H Takayama Tetrahedron Letters 47 (19), 3199-3202, 2006 | 176 | 2006 |
| Identification of opioid receptor subtypes in antinociceptive actions of supraspinally-admintstered mitragynine in mice S Thongpradichote, K Matsumoto, M Tohda, H Takayama, N Aimi, S Sakai, ... Life sciences 62 (16), 1371-1378, 1998 | 174 | 1998 |
| Metabolite profiling of alkaloids and strictosidine synthase activity in camptothecin producing plants Y Yamazaki, A Urano, H Sudo, M Kitajima, H Takayama, M Yamazaki, ... Phytochemistry 62 (3), 461-470, 2003 | 161 | 2003 |
| Protective effect of rhynchophylline and isorhynchophylline on in vitro ischemia-induced neuronal damage in the hippocampus: putative neurotransmitter receptors involved in … TH Kang, Y Murakami, H Takayama, M Kitajima, N Aimi, H Watanabe, ... Life Sciences 76 (3), 331-343, 2004 | 151 | 2004 |
| Simultaneous analysis of mitragynine, 7-hydroxymitragynine, and other alkaloids in the psychotropic plant “kratom” (Mitragyna speciosa) by LC-ESI-MS R Kikura-Hanajiri, M Kawamura, T Maruyama, M Kitajima, H Takayama, ... Forensic toxicology 27, 67-74, 2009 | 150 | 2009 |
| Prenylated flavonoids and related compounds of the Indonesian Artocarpus (Moraceae) EH Hakim, SA Achmad, LD Juliawaty, L Makmur, YM Syah, N Aimi, ... Journal of Natural Medicines 60, 161-184, 2006 | 148 | 2006 |
| Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa K Matsumoto, S Horie, H Takayama, H Ishikawa, N Aimi, D Ponglux, ... Life sciences 78 (1), 2-7, 2005 | 148 | 2005 |
| Identification of a novel selenium metabolite, Se-methyl-N-acetylselenohexosamine, in rat urine by high-performance liquid chromatography–inductively coupled plasma mass … Y Ogra, K Ishiwata, H Takayama, N Aimi, KT Suzuki Journal of Chromatography B 767 (2), 301-312, 2002 | 148 | 2002 |
