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Joao A Paulo
Joao A Paulo
Instructor in Cell Biology, Harvard Medical School
hms.harvard.edu의 이메일 확인됨 - 홈페이지
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The BioPlex network: a systematic exploration of the human interactome
EL Huttlin, L Ting, RJ Bruckner, F Gebreab, MP Gygi, J Szpyt, S Tam, ...
Cell 162 (2), 425-440, 2015
15392015
Architecture of the human interactome defines protein communities and disease networks
EL Huttlin, RJ Bruckner, JA Paulo, JR Cannon, L Ting, K Baltier, G Colby, ...
Nature 545 (7655), 505-509, 2017
15062017
Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I
K Yamamoto, A Venida, J Yano, DE Biancur, M Kakiuchi, S Gupta, ...
Nature 581 (7806), 100-105, 2020
9352020
The PINK1-PARKIN mitochondrial ubiquitylation pathway drives a program of OPTN/NDP52 recruitment and TBK1 activation to promote mitophagy
JM Heo, A Ordureau, JA Paulo, J Rinehart, JW Harper
Molecular cell 60 (1), 7-20, 2015
8592015
Dual proteome-scale networks reveal cell-specific remodeling of the human interactome
EL Huttlin, RJ Bruckner, J Navarrete-Perea, JR Cannon, K Baltier, ...
Cell 184 (11), 3022-3040. e28, 2021
7492021
Detection and quantitation of circulating human irisin by tandem mass spectrometry
MP Jedrychowski, CD Wrann, JA Paulo, KK Gerber, J Szpyt, ...
Cell metabolism 22 (4), 734-740, 2015
6002015
Excessive cell growth causes cytoplasm dilution and contributes to senescence
GE Neurohr, RL Terry, J Lengefeld, M Bonney, GP Brittingham, F Moretto, ...
cell 176 (5), 1083-1097. e18, 2019
4812019
TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples
J Li, JG Van Vranken, L Pontano Vaites, DK Schweppe, EL Huttlin, ...
Nature methods 17 (4), 399-404, 2020
4242020
Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy
A Ordureau, JM Heo, DM Duda, JA Paulo, JL Olszewski, D Yanishevski, ...
Proceedings of the National Academy of Sciences 112 (21), 6637-6642, 2015
3462015
A quantitative tissue-specific landscape of protein redox regulation during aging
H Xiao, MP Jedrychowski, DK Schweppe, EL Huttlin, Q Yu, DE Heppner, ...
Cell 180 (5), 968-983. e24, 2020
3202020
Streamlined tandem mass tag (SL-TMT) protocol: an efficient strategy for quantitative (phospho) proteome profiling using tandem mass tag-synchronous precursor selection-MS3
J Navarrete-Perea, Q Yu, SP Gygi, JA Paulo
Journal of proteome research 17 (6), 2226-2236, 2018
2972018
Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism
DE Biancur, JA Paulo, B Małachowska, M Quiles Del Rey, CM Sousa, ...
Nature communications 8 (1), 15965, 2017
2932017
Multidimensional tracking of GPCR signaling via peroxidase-catalyzed proximity labeling
J Paek, M Kalocsay, DP Staus, L Wingler, R Pascolutti, JA Paulo, SP Gygi, ...
Cell 169 (2), 338-349. e11, 2017
2842017
Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells
K Furuyama, S Chera, L van Gurp, D Oropeza, L Ghila, N Damond, ...
Nature 567 (7746), 43-48, 2019
2702019
TEX264 is an endoplasmic reticulum-resident ATG8-interacting protein critical for ER remodeling during nutrient stress
H An, A Ordureau, JA Paulo, CJ Shoemaker, V Denic, JW Harper
Molecular cell 74 (5), 891-908. e10, 2019
2632019
Probing the global cellular responses to lipotoxicity caused by saturated fatty acids
M Piccolis, LM Bond, M Kampmann, P Pulimeno, C Chitraju, CBK Jayson, ...
Molecular cell 74 (1), 32-44. e8, 2019
2502019
TMTpro-18plex: the expanded and complete set of TMTpro reagents for sample multiplexing
J Li, Z Cai, RD Bomgarden, I Pike, K Kuhn, JC Rogers, TM Roberts, ...
Journal of proteome research 20 (5), 2964-2972, 2021
2492021
Full-featured, real-time database searching platform enables fast and accurate multiplexed quantitative proteomics
DK Schweppe, JK Eng, Q Yu, D Bailey, R Rad, J Navarrete-Perea, ...
Journal of proteome research 19 (5), 2026-2034, 2020
2432020
The secreted enzyme PM20D1 regulates lipidated amino acid uncouplers of mitochondria
JZ Long, KJ Svensson, LA Bateman, H Lin, T Kamenecka, IA Lokurkar, ...
Cell 166 (2), 424-435, 2016
2382016
Two distinct types of E3 ligases work in unison to regulate substrate ubiquitylation
DC Scott, DY Rhee, DM Duda, IR Kelsall, JL Olszewski, JA Paulo, ...
Cell 166 (5), 1198-1214. e24, 2016
2372016
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학술자료 1–20