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Gen-Sheng Feng
Gen-Sheng Feng
ucsd.edu의 이메일 확인됨
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Relationship between interferon‐γ, indoleamine 2, 3‐dioxygenase, and tryptophan catabolism
MW Taylor, G Feng
The FASEB Journal 5 (11), 2516-2522, 1991
13621991
SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases
GS Feng, CC Hui, T Pawson
Science 259 (5101), 1607-1611, 1993
8421993
Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4
LEM Marengère, P Waterhouse, GS Duncan, HW Mittrücker, GS Feng, ...
Science 272 (5265), 1170-1173, 1996
6551996
Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp‐2
TM Saxton, M Henkemeyer, S Gasca, R Shen, DJ Rossi, F Shalaby, ...
The EMBO journal, 1997
5661997
Shp-2 tyrosine phosphatase functions as a negative regulator of the interferon-stimulated Jak/STAT pathway
M You, DH Yu, GS Feng
Molecular and cellular biology 19 (3), 2416-2424, 1999
5121999
Protein-tyrosine phosphatase Shp-2 regulates cell spreading, migration, and focal adhesion
DH Yu, CK Qu, O Henegariu, X Lu, GS Feng
Journal of Biological Chemistry 273 (33), 21125-21131, 1998
5111998
The insulin receptor substrate 1 associates with the SH2-containing phosphotyrosine phosphatase Syp
MR Kuhne, T Pawson, GE Lienhard, GS Feng
Journal of Biological Chemistry 268 (16), 11479-11481, 1993
4791993
PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase
RJ Chan, GS Feng
Blood 109 (3), 862-867, 2007
3942007
Shp-2 tyrosine phosphatase: signaling one cell or many
GS Feng
Experimental cell research 253 (1), 47-54, 1999
3821999
Ptpn11/Shp2 acts as a tumor suppressor in hepatocellular carcinogenesis
EA Bard-Chapeau, S Li, J Ding, SS Zhang, HH Zhu, F Princen, DD Fang, ...
Cancer cell 19 (5), 629-639, 2011
3722011
SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production
H An, W Zhao, J Hou, Y Zhang, Y Xie, Y Zheng, H Xu, C Qian, J Zhou, ...
Immunity 25 (6), 919-928, 2006
3002006
Molecular mechanism for the Shp-2 tyrosine phosphatase function in promoting growth factor stimulation of Erk activity
ZQ Shi, DH Yu, M Park, M Marshall, GS Feng
Molecular and cellular biology, 2000
2952000
Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten mice.
M Kozlowski, I Mlinaric-Rascan, GS Feng, R Shen, T Pawson, ...
Journal of Experimental Medicine 178 (6), 2157-2163, 1993
2931993
Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
EE Zhang, E Chapeau, K Hagihara, GS Feng
Proceedings of the National Academy of Sciences 101 (45), 16064-16069, 2004
2872004
Nuclear factor high‐mobility group box1 mediating the activation of Toll‐like receptor 4 signaling in hepatocytes in the early stage of nonalcoholic fatty liver disease in mice
L Li, L Chen, L Hu, Y Liu, HY Sun, J Tang, YJ Hou, YX Chang, QQ Tu, ...
Hepatology 54 (5), 1620-1630, 2011
2752011
The 64-kDa protein that associates with the platelet-derived growth factor receptor beta subunit via Tyr-1009 is the SH2-containing phosphotyrosine phosphatase Syp.
A Kazlauskas, GS Feng, T Pawson, M Valius
Proceedings of the National Academy of Sciences 90 (15), 6939-6943, 1993
2691993
Force‐dependent integrin–cytoskeleton linkage formation requires downregulation of focal complex dynamics by Shp2
G Von Wichert, B Haimovich, GS Feng, MP Sheetz
The EMBO journal, 2003
2622003
Phosphotyrosine phosphatases with SH2 domains: regulators of signal transduction
GS Feng, T Pawson
Trends in Genetics 10 (2), 54-58, 1994
2591994
Prognostic significance of AMPK activation and therapeutic effects of metformin in hepatocellular carcinoma
L Zheng, W Yang, F Wu, C Wang, L Yu, L Tang, B Qiu, Y Li, L Guo, M Wu, ...
Clinical cancer research 19 (19), 5372-5380, 2013
2562013
Hepatic transforming growth factor beta gives rise to tumor‐initiating cells and promotes liver cancer development
K Wu, J Ding, C Chen, W Sun, BF Ning, W Wen, L Huang, T Han, W Yang, ...
Hepatology 56 (6), 2255-2267, 2012
2402012
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