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Juan R. Cubillos-Ruiz, Ph.D.
Juan R. Cubillos-Ruiz, Ph.D.
Weill Cornell Medicine - Cornell University
med.cornell.edu의 이메일 확인됨 - 홈페이지
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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
63082018
Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation
H Zhang, D Freitas, HS Kim, K Fabijanic, Z Li, H Chen, MT Mark, H Molina, ...
Nature cell biology 20 (3), 332-343, 2018
15542018
Endoplasmic reticulum stress signals in the tumour and its microenvironment
X Chen, JR Cubillos-Ruiz
Nature Reviews Cancer 21 (2), 71-88, 2021
8612021
ER stress sensor XBP1 controls anti-tumor immunity by disrupting dendritic cell homeostasis
JR Cubillos-Ruiz, PC Silberman, MR Rutkowski, S Chopra, ...
Cell 161 (7), 1527-1538, 2015
8412015
Tumorigenic and immunosuppressive effects of endoplasmic reticulum stress in cancer
JR Cubillos-Ruiz, SE Bettigole, LH Glimcher
Cell 168 (4), 692-706, 2017
8062017
Ovarian cancer progression is controlled by phenotypic changes in dendritic cells
UK Scarlett, MR Rutkowski, AM Rauwerdink, J Fields, X Escovar-Fadul, ...
Journal of Experimental Medicine 209 (3), 495-506, 2012
3882012
IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity
M Song, TA Sandoval, CS Chae, S Chopra, C Tan, MR Rutkowski, ...
Nature 562 (7727), 423-428, 2018
3432018
Somatic mutations and cell identity linked by Genotyping of Transcriptomes
AS Nam, KT Kim, R Chaligne, F Izzo, C Ang, J Taylor, RM Myers, ...
Nature 571 (7765), 355-360, 2019
2892019
Polyethylenimine-based siRNA nanocomplexes reprogram tumor-associated dendritic cells via TLR5 to elicit therapeutic antitumor immunity
JR Cubillos-Ruiz, X Engle, UK Scarlett, D Martinez, A Barber, R Elgueta, ...
The Journal of clinical investigation 119 (8), 2231-2244, 2009
2842009
Apoptotic cell death in disease—Current understanding of the NCCD 2023
I Vitale, F Pietrocola, E Guilbaud, SA Aaronson, JM Abrams, D Adam, ...
Cell Death & Differentiation 30 (5), 1097-1154, 2023
1992023
In situ stimulation of CD40 and toll-like receptor 3 transforms ovarian cancer–infiltrating dendritic cells from immunosuppressive to immunostimulatory cells
UK Scarlett, JR Cubillos-Ruiz, YC Nesbeth, DG Martinez, X Engle, ...
Cancer research 69 (18), 7329-7337, 2009
1952009
Reprogramming Tumor-Associated Dendritic Cells In Vivo Using miRNA Mimetics Triggers Protective Immunity against Ovarian Cancer
JR Cubillos-Ruiz, JR Baird, AJ Tesone, MR Rutkowski, UK Scarlett, ...
Cancer research 72 (7), 1683-1693, 2012
1772012
Depletion of dendritic cells delays ovarian cancer progression by boosting antitumor immunity
E Huarte, JR Cubillos-Ruiz, YC Nesbeth, UK Scarlett, DG Martinez, ...
Cancer research 68 (18), 7684-7691, 2008
1772008
Antifungal mechanisms by which a novel Pseudomonas aeruginosa phenazine toxin kills Candida albicans in biofilms
DK Morales, NJ Jacobs, S Rajamani, M Krishnamurthy, JR Cubillos‐Ruiz, ...
Molecular microbiology 78 (6), 1379-1392, 2010
1702010
The unfolded protein response mediator PERK governs myeloid cell-driven immunosuppression in tumors through inhibition of STING signaling
E Mohamed, RA Sierra, J Trillo-Tinoco, Y Cao, P Innamarato, KK Payne, ...
Immunity 52 (4), 668-682. e7, 2020
1562020
Dendritic cell metabolism and function in tumors
P Giovanelli, TA Sandoval, JR Cubillos-Ruiz
Trends in immunology 40 (8), 699-718, 2019
1522019
CD4+ T cells elicit host immune responses to MHC class II− ovarian cancer through CCL5 secretion and CD40-mediated licensing of dendritic cells
YC Nesbeth, DG Martinez, S Toraya, UK Scarlett, JR Cubillos-Ruiz, ...
The Journal of Immunology 184 (10), 5654-5662, 2010
1382010
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression
Y Cao, J Trillo-Tinoco, RA Sierra, C Anadon, W Dai, E Mohamed, L Cen, ...
Nature communications 10 (1), 1280, 2019
1342019
BH3‐only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α
DA Rodriguez, S Zamorano, F Lisbona, D Rojas‐Rivera, H Urra, ...
The EMBO journal 31 (10), 2322-2335, 2012
1312012
IRE1α–XBP1 signaling in leukocytes controls prostaglandin biosynthesis and pain
S Chopra, P Giovanelli, PA Alvarado-Vazquez, S Alonso, M Song, ...
Science 365 (6450), eaau6499, 2019
1252019
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