| Geroscience: linking aging to chronic disease BK Kennedy, SL Berger, A Brunet, J Campisi, AM Cuervo, ES Epel, ... Cell 159 (4), 709-713, 2014 | 2390 | 2014 |
| Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients M Kaeberlein, RW Powers III, KK Steffen, EA Westman, D Hu, N Dang, ... Science 310 (5751), 1193-1196, 2005 | 1597 | 2005 |
| Cellular senescence promotes adverse effects of chemotherapy and cancer relapse M Demaria, MN O'Leary, J Chang, L Shao, SU Liu, F Alimirah, K Koenig, ... Cancer discovery 7 (2), 165-176, 2017 | 1266 | 2017 |
| Extension of chronological life span in yeast by decreased TOR pathway signaling RW Powers, M Kaeberlein, SD Caldwell, BK Kennedy, S Fields Genes & development 20 (2), 174-184, 2006 | 1208 | 2006 |
| Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population ME Levine, JA Suarez, S Brandhorst, P Balasubramanian, CW Cheng, ... Cell metabolism 19 (3), 407-417, 2014 | 1115 | 2014 |
| A periodic diet that mimics fasting promotes multi-system regeneration, enhanced cognitive performance, and healthspan S Brandhorst, IY Choi, M Wei, CW Cheng, S Sedrakyan, G Navarrete, ... Cell metabolism 22 (1), 86-99, 2015 | 975 | 2015 |
| Substrate-specific activation of sirtuins by resveratrol M Kaeberlein, T McDonagh, B Heltweg, J Hixon, EA Westman, ... Journal of Biological Chemistry 280 (17), 17038-17045, 2005 | 938 | 2005 |
| Sirtuins in aging and age-related disease VD Longo, BK Kennedy Cell 126 (2), 257-268, 2006 | 775 | 2006 |
| Histone H4 lysine 16 acetylation regulates cellular lifespan W Dang, KK Steffen, R Perry, JA Dorsey, FB Johnson, A Shilatifard, ... Nature 459 (7248), 802-807, 2009 | 755 | 2009 |
| Replicative and chronological aging in Saccharomyces cerevisiae VD Longo, GS Shadel, M Kaeberlein, B Kennedy Cell metabolism 16 (1), 18-31, 2012 | 707 | 2012 |
| Interventions to slow aging in humans: are we ready? VD Longo, A Antebi, A Bartke, N Barzilai, HM Brown‐Borg, C Caruso, ... Aging cell 14 (4), 497-510, 2015 | 654 | 2015 |
| Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae BK Kennedy, NR Austriaco Jr, J Zhang, L Guarente Cell 80 (3), 485-496, 1995 | 601 | 1995 |
| The mechanistic target of rapamycin: the grand conducTOR of metabolism and aging BK Kennedy, DW Lamming Cell metabolism 23 (6), 990-1003, 2016 | 562 | 2016 |
| Sir2-independent life span extension by calorie restriction in yeast M Kaeberlein, KT Kirkland, S Fields, BK Kennedy PLoS biology 2 (9), e296, 2004 | 542 | 2004 |
| The TOR pathway comes of age MN Stanfel, LS Shamieh, M Kaeberlein, BK Kennedy Biochimica et Biophysica Acta (BBA)-General Subjects 1790 (10), 1067-1074, 2009 | 530 | 2009 |
| Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4 KK Steffen, VL MacKay, EO Kerr, M Tsuchiya, D Hu, LA Fox, N Dang, ... Cell 133 (2), 292-302, 2008 | 525 | 2008 |
| LMNA mutations in atypical Werner's syndrome L Chen, L Lee, BA Kudlow, HG Dos Santos, O Sletvold, Y Shafeghati, ... The Lancet 362 (9382), 440-445, 2003 | 509 | 2003 |
| Progeria syndromes and ageing: what is the connection? CR Burtner, BK Kennedy Nature reviews Molecular cell biology 11 (8), 567-578, 2010 | 500 | 2010 |
| Redistribution of silencing proteins from telomeres to the nucleolus is associated with extension of life span in S. cerevisiae BK Kennedy, M Gotta, DA Sinclair, K Mills, DS McNabb, M Murthy, ... Cell 89 (3), 381-391, 1997 | 490 | 1997 |
| NPAT links cyclin E–Cdk2 to the regulation of replication-dependent histone gene transcription J Zhao, BK Kennedy, BD Lawrence, DA Barbie, AG Matera, JA Fletcher, ... Genes & development 14 (18), 2283-2297, 2000 | 456 | 2000 |
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