| Resolving the fibrotic niche of human liver cirrhosis at single-cell level P Ramachandran, R Dobie, JR Wilson-Kanamori, EF Dora, ... Nature 575 (7783), 512-518, 2019 | 1298 | 2019 |
| The role of focal-adhesion kinase in cancer—a new therapeutic opportunity GW McLean, NO Carragher, E Avizienyte, J Evans, VG Brunton, ... Nature Reviews Cancer 5 (7), 505-515, 2005 | 1273 | 2005 |
| Screening out irrelevant cell-based models of disease P Horvath, N Aulner, M Bickle, AM Davies, ED Nery, D Ebner, ... Nature reviews Drug discovery 15 (11), 751-769, 2016 | 561 | 2016 |
| The calpain system and cancer SJ Storr, NO Carragher, MC Frame, T Parr, SG Martin Nature Reviews Cancer 11 (5), 364-374, 2011 | 495 | 2011 |
| Focal adhesion and actin dynamics: a place where kinases and proteases meet to promote invasion NO Carragher, MC Frame Trends in cell biology 14 (5), 241-249, 2004 | 457 | 2004 |
| v-Src's hold over actin and cell adhesions MC Frame, VJ Fincham, NO Carragher, JA Wyke Nature Reviews Molecular Cell Biology 3 (4), 233-245, 2002 | 408 | 2002 |
| Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach JT Weiss, JC Dawson, KG Macleod, W Rybski, C Fraser, ... Nature communications 5 (1), 3277, 2014 | 347 | 2014 |
| SRC-mediated phosphorylation of focal adhesion kinase couples actin and adhesion dynamics to survival signaling MA Westhoff, B Serrels, VJ Fincham, MC Frame, NO Carragher Molecular and cellular biology 24 (18), 8113-8133, 2004 | 321 | 2004 |
| Degraded collagen fragments promote rapid disassembly of smooth muscle focal adhesions that correlates with cleavage of pp125FAK, paxillin, and talin NO Carragher, B Levkau, R Ross, EW Raines Journal of Cell Biology 147 (3), 619-630, 1999 | 304 | 1999 |
| A novel role for FAK as a protease-targeting adaptor protein: regulation by p42 ERK and Src NO Carragher, MA Westhoff, VJ Fincham, MD Schaller, MC Frame Current biology 13 (16), 1442-1450, 2003 | 255 | 2003 |
| Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530 TP Green, M Fennell, R Whittaker, J Curwen, V Jacobs, J Allen, A Logie, ... Molecular oncology 3 (3), 248-261, 2009 | 253 | 2009 |
| Paradox-breaking RAF inhibitors that also target SRC are effective in drug-resistant BRAF mutant melanoma MR Girotti, F Lopes, N Preece, D Niculescu-Duvaz, A Zambon, L Davies, ... Cancer cell 27 (1), 85-96, 2015 | 240 | 2015 |
| Calpain inhibition: a therapeutic strategy targeting multiple disease states NO Carragher Current pharmaceutical design 12 (5), 615-638, 2006 | 239 | 2006 |
| Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling: potential implications in atherosclerosis and lymphangioleiomyomatosis N Ferri, NO Carragher, EW Raines The American journal of pathology 164 (5), 1575-1585, 2004 | 225 | 2004 |
| Calpain 2 and Src dependence distinguishes mesenchymal and amoeboid modes of tumour cell invasion: a link to integrin function NO Carragher, SM Walker, LA Scott Carragher, F Harris, TK Sawyer, ... Oncogene 25 (42), 5726-5740, 2006 | 219 | 2006 |
| Development and bioorthogonal activation of palladium-labile prodrugs of gemcitabine JT Weiss, JC Dawson, C Fraser, W Rybski, C Torres-Sánchez, M Bradley, ... Journal of medicinal chemistry 57 (12), 5395-5404, 2014 | 215 | 2014 |
| Realizing the promise of reverse phase protein arrays for clinical, translational, and basic research: a workshop report: the RPPA (Reverse Phase Protein Array) society R Akbani, KF Becker, N Carragher, T Goldstein, L De Koning, U Korf, ... Molecular & cellular proteomics 13 (7), 1625-1643, 2014 | 214 | 2014 |
| FLT1 signaling in metastasis-associated macrophages activates an inflammatory signature that promotes breast cancer metastasis BZ Qian, H Zhang, J Li, T He, EJ Yeo, DYH Soong, NO Carragher, ... Journal of Experimental Medicine 212 (9), 1433-1448, 2015 | 213 | 2015 |
| Comparison of methods for image-based profiling of cellular morphological responses to small-molecule treatment V Ljosa, PD Caie, R Ter Horst, KL Sokolnicki, EL Jenkins, S Daya, ... Journal of biomolecular screening 18 (10), 1321-1329, 2013 | 194 | 2013 |
| High-content phenotypic profiling of drug response signatures across distinct cancer cells PD Caie, RE Walls, A Ingleston-Orme, S Daya, T Houslay, R Eagle, ... Molecular cancer therapeutics 9 (6), 1913-1926, 2010 | 189 | 2010 |