Temporal regulation of EGF signalling networks by the scaffold protein Shc1 Y Zheng, C Zhang, DR Croucher, MA Soliman, N St-Denis, A Pasculescu, ... Nature 499 (7457), 166-171, 2013 | 326 | 2013 |
CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan C Vennin, P Mélénec, R Rouet, M Nobis, AS Cazet, KJ Murphy, ... Nature communications 10 (1), 3637, 2019 | 240 | 2019 |
Crosstalk and signaling switches in mitogen-activated protein kinase cascades D Fey, DR Croucher, W Kolch, BN Kholodenko Frontiers in physiology 3, 355, 2012 | 217 | 2012 |
Tyrosine phosphorylation profiling reveals the signaling network characteristics of Basal breast cancer cells F Hochgräfe, L Zhang, SA O'Toole, BC Browne, M Pinese, A Porta Cubas, ... Cancer research 70 (22), 9391-9401, 2010 | 214 | 2010 |
Revisiting the biological roles of PAI2 (SERPINB2) in cancer DR Croucher, DN Saunders, S Lobov, M Ranson Nature Reviews Cancer 8 (7), 535-545, 2008 | 214 | 2008 |
The extracellular matrix as a key regulator of intracellular signalling networks JF Hastings, JN Skhinas, D Fey, DR Croucher, TR Cox British journal of pharmacology 176 (1), 82-92, 2019 | 211 | 2019 |
Nedd4 controls animal growth by regulating IGF-1 signaling XR Cao, NL Lill, N Boase, PP Shi, DR Croucher, H Shan, J Qu, ... Science signaling 1 (38), ra5-ra5, 2008 | 205 | 2008 |
Signaling pathway models as biomarkers: Patient-specific simulations of JNK activity predict the survival of neuroblastoma patients D Fey, M Halasz, D Dreidax, SP Kennedy, JF Hastings, N Rauch, ... Science signaling 8 (408), ra130-ra130, 2015 | 173 | 2015 |
Tissue‐type plasminogen activator requires a co‐receptor to enhance NMDA receptor function AL Samson, ST Nevin, D Croucher, B Niego, PB Daniel, TW Weiss, ... Journal of neurochemistry 107 (4), 1091-1101, 2008 | 145 | 2008 |
Temporal profiling of the breast tumour microenvironment reveals collagen XII as a driver of metastasis M Papanicolaou, AL Parker, M Yam, EC Filipe, SZ Wu, JL Chitty, K Wyllie, ... Nature communications 13 (1), 4587, 2022 | 127 | 2022 |
Axl-EGFR receptor tyrosine kinase hetero-interaction provides EGFR with access to pro-invasive signalling in cancer cells M Vouri, DR Croucher, SP Kennedy, Q An, GJ Pilkington, S Hafizi Oncogenesis 5 (10), e266-e266, 2016 | 120 | 2016 |
Involvement of Lyn and the atypical kinase SgK269/PEAK1 in a basal breast cancer signaling pathway DR Croucher, F Hochgräfe, L Zhang, L Liu, RJ Lyons, D Rickwood, ... Cancer research 73 (6), 1969-1980, 2013 | 102 | 2013 |
Activin A is essential for neurogenesis following neurodegeneration A Abdipranoto-Cowley, JS Park, D Croucher, J Daniel, S Henshall, ... Stem cells 27 (6), 1330-1346, 2009 | 99 | 2009 |
MTOR signaling orchestrates stress-induced mutagenesis, facilitating adaptive evolution in cancer A Cipponi, DL Goode, J Bedo, MJ McCabe, M Pajic, DR Croucher, ... Science 368 (6495), 1127-1131, 2020 | 96 | 2020 |
The under-appreciated promiscuity of the epidermal growth factor receptor family SP Kennedy, JF Hastings, JZR Han, DR Croucher Frontiers in cell and developmental biology 4, 88, 2016 | 87 | 2016 |
Signalling by protein phosphatases and drug development: a systems‐centred view LK Nguyen, D Matallanas, DR Croucher, A Von Kriegsheim, ... The FEBS journal 280 (2), 751-765, 2013 | 73 | 2013 |
Intravital FRAP imaging using an E-cadherin-GFP mouse reveals disease-and drug-dependent dynamic regulation of cell-cell junctions in live tissue Z Erami, D Herrmann, SC Warren, M Nobis, EJ McGhee, MC Lucas, ... Cell reports 14 (1), 152-167, 2016 | 72 | 2016 |
Bimolecular complementation affinity purification (BiCAP) reveals dimer-specific protein interactions for ERBB2 dimers DR Croucher, M Iconomou, JF Hastings, SP Kennedy, JZR Han, ... Science signaling 9 (436), ra69-ra69, 2016 | 69 | 2016 |
Intravital imaging to monitor therapeutic response in moving hypoxic regions resistant to PI3K pathway targeting in pancreatic cancer JRW Conway, SC Warren, D Herrmann, KJ Murphy, AS Cazet, C Vennin, ... Cell reports 23 (11), 3312-3326, 2018 | 68 | 2018 |
Kinetic analysis of plasminogen activator inhibitor type-2: urokinase complex formation and subsequent internalisation by carcinoma cell lines F Al-Ejeh, D Croucher, M Ranson Experimental cell research 297 (1), 259-271, 2004 | 68 | 2004 |