First human trial of a DNA-based vaccine for treatment of human immunodeficiency virus type 1 infection: safety and host response RR MacGregor, JD Boyer, KE Ugen, KE Lacy, SJ Gluckman, ... Journal of infectious diseases 178 (1), 92-100, 1998 | 818 | 1998 |
Protection of chimpanzees from high-dose heterologous HIV-1 challenge by DNA vaccination JD Boyer, KE Ugen, B Wang, M Agadjanyan, L Gilbert, ML Bagarazzi, ... Nature medicine 3 (5), 526-532, 1997 | 487 | 1997 |
In vivo engineering of a cellular immune response by coadministration of IL-12 expression vector with a DNA immunogen. JJ Kim, V Ayyavoo, ML Bagarazzi, MA Chattergoon, K Dang, B Wang, ... Journal of immunology (Baltimore, Md.: 1950) 158 (2), 816-826, 1997 | 476 | 1997 |
Modulation of amplitude and direction of in vivo immune responses by co‐administration of cytokine gene expression cassettes with DNA immunogens JJ Kim, NN Trivedi, LK Nottingham, L Morrison, A Tsai, Y Hu, ... European journal of immunology 28 (3), 1089-1103, 1998 | 322 | 1998 |
Direct-acting antiviral prophylaxis in kidney transplantation from hepatitis C virus–infected donors to noninfected recipients: an open-label nonrandomized trial CM Durand, MG Bowring, DM Brown, MA Chattergoon, G Massaccesi, ... Annals of internal medicine 168 (8), 533-540, 2018 | 311 | 2018 |
Engineering of in vivo immune responses to DNA immunization via codelivery of costimulatory molecule genes JJ Kirn, ML Bagarazzi, N Trivedi, Y Hu, K Kazahaya, DM Wilson, ... Nature biotechnology 15 (7), 641-646, 1997 | 305 | 1997 |
Specific immune induction following DNA-based immunization through in vivo transfection and activation of macrophages/antigen-presenting cells MA Chattergoon, TM Robinson, JD Boyer, DB Weiner The Journal of Immunology 160 (12), 5707-5718, 1998 | 287 | 1998 |
TGFβ1-mediated SMAD3 enhances PD-1 expression on antigen-specific T cells in cancer BV Park, ZT Freeman, A Ghasemzadeh, MA Chattergoon, ... Cancer discovery 6 (12), 1366-1381, 2016 | 255 | 2016 |
Coimmunization with an optimized IL-15 plasmid results in enhanced function and longevity of CD8 T cells that are partially independent of CD4 T cell help MA Kutzler, TM Robinson, MA Chattergoon, DK Choo, AY Choo, PY Choe, ... The Journal of Immunology 175 (1), 112-123, 2005 | 228 | 2005 |
HIV and HCV activate the inflammasome in monocytes and macrophages via endosomal Toll-like receptors without induction of type 1 interferon MA Chattergoon, R Latanich, J Quinn, ME Winter, RW Buckheit 3rd, ... PLoS pathogens 10 (5), e1004082, 2014 | 198 | 2014 |
Genetic immunization: a new era in vaccines and immune therapeutics M Chattergoon, J Boyer, DB Weiner The FASEB journal 11 (10), 753-763, 1997 | 178 | 1997 |
Identification of crucial residues for the antibacterial activity of the proline‐rich peptide, pyrrhocoricin G Kragol, R Hoffmann, MA Chattergoon, S Lovas, M Cudic, P Bulet, ... European journal of biochemistry 269 (17), 4226-4237, 2002 | 170 | 2002 |
Targeted antigen delivery to antigen–presenting cells including dendritic cells by engineered Fas-mediated apoptosis MA Chattergoon, JJ Kim, JS Yang, TM Robinson, DJ Lee, T Dentchev, ... Nature biotechnology 18 (9), 974-979, 2000 | 162 | 2000 |
Host cell killing by the West Nile Virus NS2B–NS3 proteolytic complex: NS3 alone is sufficient to recruit caspase-8-based apoptotic pathway MP Ramanathan, JA Chambers, P Pankhong, M Chattergoon, ... Virology 345 (1), 56-72, 2006 | 158 | 2006 |
DNA vaccination with HIV-1 expressing constructs elicits immune responses in humans KE Ugen, SB Nyland, JD Boyer, C Vidal, L Lera, S Rasheid, ... Vaccine 16 (19), 1818-1821, 1998 | 139 | 1998 |
Enhancement of cellular immune response in HIV-1 seropositive individuals: a DNA-based trial JD Boyer, MA Chattergoon, KE Ugen, A Shah, M Bennett, A Cohen, ... Clinical Immunology 90 (1), 100-107, 1999 | 126 | 1999 |
Molecular and immunological analysis of genetic prostate specific antigen (PSA) vaccine JJ Kim, NN Trivedi, DM Wilson, S Mahalingam, L Morrison, A Tsai, ... Oncogene 17 (24), 3125-3135, 1998 | 111 | 1998 |
Monocytes activate natural killer cells via inflammasome-induced interleukin 18 in response to hepatitis C virus replication E Serti, JM Werner, M Chattergoon, AL Cox, V Lohmann, B Rehermann Gastroenterology 147 (1), 209-220. e3, 2014 | 106 | 2014 |
Mechanism of HIV-1 viral protein R-induced apoptosis K Muthumani, AY Choo, DS Hwang, MA Chattergoon, NN Dayes, ... Biochemical and biophysical research communications 304 (3), 583-592, 2003 | 106 | 2003 |
Allosteric coupling between Mn2+ and dsDNA controls the catalytic efficiency and fidelity of cGAS RM Hooy, G Massaccesi, KE Rousseau, MA Chattergoon, J Sohn Nucleic acids research 48 (8), 4435-4447, 2020 | 81 | 2020 |