| Extreme electric fields power catalysis in the active site of ketosteroid isomerase SD Fried, S Bagchi, SG Boxer Science 346 (6216), 1510-1514, 2014 | 533 | 2014 |
| Measuring electric fields and noncovalent interactions using the vibrational stark effect SD Fried, SG Boxer Accounts of chemical research 48 (4), 998-1006, 2015 | 523 | 2015 |
| Electric fields and enzyme catalysis SD Fried, SG Boxer Annual review of biochemistry 86 (1), 387-415, 2017 | 434 | 2017 |
| Measuring electrostatic fields in both hydrogen-bonding and non-hydrogen-bonding environments using carbonyl vibrational probes SD Fried, S Bagchi, SG Boxer Journal of the American Chemical Society 135 (30), 11181-11192, 2013 | 235 | 2013 |
| Quantum delocalization of protons in the hydrogen-bond network of an enzyme active site L Wang, SD Fried, SG Boxer, TE Markland Proceedings of the National Academy of Sciences 111 (52), 18454-18459, 2014 | 154 | 2014 |
| A solvatochromic model calibrates nitriles’ vibrational frequencies to electrostatic fields S Bagchi, SD Fried, SG Boxer Journal of the American Chemical Society 134 (25), 10373-10376, 2012 | 142 | 2012 |
| Solvent-induced infrared frequency shifts in aromatic nitriles are quantitatively described by the vibrational Stark effect NM Levinson, SD Fried, SG Boxer The journal of physical chemistry B 116 (35), 10470-10476, 2012 | 131 | 2012 |
| Calculations of the electric fields in liquid solutions SD Fried, LP Wang, SG Boxer, P Ren, VS Pande The Journal of Physical Chemistry B 117 (50), 16236-16248, 2013 | 117 | 2013 |
| Rapid discovery and evolution of orthogonal aminoacyl-tRNA synthetase–tRNA pairs D Cervettini, S Tang, SD Fried, JCW Willis, LFH Funke, LJ Colwell, ... Nature Biotechnology 38 (8), 989-999, 2020 | 113 | 2020 |
| Controlling orthogonal ribosome subunit interactions enables evolution of new function WH Schmied, Z Tnimov, C Uttamapinant, CD Rae, SD Fried, JW Chin Nature 564 (7736), 444-448, 2018 | 110 | 2018 |
| Ribosome Subunit Stapling for Orthogonal Translation in E. coli SD Fried, WH Schmied, C Uttamapinant, JW Chin Angewandte Chemie International Edition 54 (43), 12791-12794, 2015 | 97 | 2015 |
| Modeling organochlorine compounds and the σ-hole effect using a polarizable multipole force field X Mu, Q Wang, LP Wang, SD Fried, JP Piquemal, KN Dalby, P Ren The Journal of Physical Chemistry B 118 (24), 6456-6465, 2014 | 96 | 2014 |
| Nonrefoldability is Pervasive Across the E. coli Proteome P To, B Whitehead, HE Tarbox, SD Fried Journal of the American Chemical Society 143 (30), 11435-11448, 2021 | 62 | 2021 |
| A preorganized electric field leads to minimal geometrical reorientation in the catalytic reaction of ketosteroid isomerase Y Wu, SD Fried, SG Boxer Journal of the American Chemical Society 142 (22), 9993-9998, 2020 | 62 | 2020 |
| How synonymous mutations alter enzyme structure and function over long timescales Y Jiang, SS Neti, I Sitarik, P Pradhan, P To, Y Xia, SD Fried, SJ Booker, ... Nature Chemistry 15 (3), 308-318, 2023 | 58 | 2023 |
| Peptides before and during the nucleotide world: An origins story emphasizing cooperation between proteins and nucleic acids SD Fried, K Fujishima, M Makarov, I Cherepashuk, K Hlouchova Journal of the Royal Society Interface 19 (187), 20210641, 2022 | 57 | 2022 |
| Tagging and enriching proteins enables cell-specific proteomics TS Elliott, A Bianco, FM Townsley, SD Fried, JW Chin Cell chemical biology 23 (7), 805-815, 2016 | 56 | 2016 |
| Quantitative dissection of hydrogen bond-mediated proton transfer in the ketosteroid isomerase active site PA Sigala, AT Fafarman, JP Schwans, SD Fried, TD Fenn, JMM Caaveiro, ... Proceedings of the National Academy of Sciences 110 (28), E2552-E2561, 2013 | 44 | 2013 |
| Proton network flexibility enables robustness and large electric fields in the ketosteroid isomerase active site L Wang, SD Fried, TE Markland The Journal of Physical Chemistry B 121 (42), 9807-9815, 2017 | 40 | 2017 |
| Universal protein misfolding intermediates can bypass the proteostasis network and remain soluble and less functional DA Nissley, Y Jiang, F Trovato, I Sitarik, KB Narayan, P To, Y Xia, ... Nature Communications 13 (1), 3081, 2022 | 37 | 2022 |
Sayan BagchiPrincipal Scientist, National Chemical LaboratoryPatvirtintas el. paštas ncl.res.in
