Stebėti
Emma Briggs
Emma Briggs
Patvirtintas el. paštas ed.ac.uk
Pavadinimas
Cituota
Cituota
Metai
Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei
JA Stortz, TD Serafim, S Alsford, J Wilkes, F Fernandez-Cortes, ...
PLoS pathogens 13 (7), e1006477, 2017
542017
Single-cell transcriptomic analysis of bloodstream Trypanosoma brucei reconstructs cell cycle progression and developmental quorum sensing
EM Briggs, F Rojas, R McCulloch, KR Matthews, TD Otto
Nature communications 12 (1), 5268, 2021
522021
Ribonuclease H1-targeted R-loops in surface antigen gene expression sites can direct trypanosome immune evasion
E Briggs, K Crouch, L Lemgruber, C Lapsley, R McCulloch
PLoS genetics 14 (12), e1007729, 2018
472018
The effects of adding fluoride compounds to a fluoride-free glass ionomer cement on subsequent fluoride and sodium release
JA Williams, E Briggs, RW Billington, GJ Pearson
Biomaterials 24 (7), 1301-1308, 2003
422003
Genome-wide mapping reveals conserved and diverged R-loop activities in the unusual genetic landscape of the African trypanosome genome
E Briggs, G Hamilton, K Crouch, C Lapsley, R McCulloch
Nucleic acids research 46 (22), 11789-11805, 2018
392018
Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection
JF Quintana, P Chandrasegaran, MC Sinton, EM Briggs, TD Otto, ...
Nature communications 13 (1), 5752, 2022
372022
Trypanosoma brucei ribonuclease H2A is an essential R-loop processing enzyme whose loss causes DNA damage during transcription initiation and antigenic …
E Briggs, K Crouch, L Lemgruber, G Hamilton, C Lapsley, R McCulloch
Nucleic Acids Research 47 (17), 9180-9197, 2019
352019
Evaluation of mechanisms that may generate DNA lesions triggering antigenic variation in African trypanosomes
MS da Silva, GA Hovel-Miner, EM Briggs, MC Elias, R McCulloch
PLoS pathogens 14 (11), e1007321, 2018
292018
Read, write, adapt: challenges and opportunities during kinetoplastid genome replication
JD Damasceno, CA Marques, J Black, E Briggs, R McCulloch
Trends in Genetics 37 (1), 21-34, 2021
212021
Emergence and adaptation of the cellular machinery directing antigenic variation in the African trypanosome
J Faria, EM Briggs, JA Black, R McCulloch
Current opinion in microbiology 70, 102209, 2022
172022
Genome maintenance functions of a putative Trypanosoma brucei translesion DNA polymerase include telomere association and a role in antigenic variation
AZ Leal, M Schwebs, E Briggs, N Weisert, H Reis, L Lemgruber, K Luko, ...
Nucleic acids research 48 (17), 9660-9680, 2020
162020
Profiling the bloodstream form and procyclic form Trypanosoma brucei cell cycle using single-cell transcriptomics
EM Briggs, CA Marques, GR Oldrieve, J Hu, TD Otto, KR Matthews
Elife 12, e86325, 2023
142023
Application of single-cell transcriptomics to kinetoplastid research
EM Briggs, FSL Warren, KR Matthews, R McCulloch, TD Otto
Parasitology 148 (10), 1223-1236, 2021
122021
RAD51-mediated R-loop formation acts to repair transcription-associated DNA breaks driving antigenic variation in Trypanosoma brucei
MJ Girasol, M Krasilnikova, CA Marques, JD Damasceno, C Lapsley, ...
Proceedings of the National Academy of Sciences 120 (48), e2309306120, 2023
102023
The developmental hierarchy and scarcity of replicative slender trypanosomes in blood challenges their role in infection maintenance
SD Larcombe, EM Briggs, N Savill, B Szoor, KR Matthews
Proceedings of the National Academy of Sciences 120 (42), e2306848120, 2023
72023
TrAGEDy: trajectory alignment of gene expression dynamics
RF Laidlaw, EM Briggs, KR Matthews, R McCulloch, TD Otto
bioRxiv, 2022.12. 21.521424, 2022
62022
Paving the way: contributions of big data to apicomplexan and kinetoplastid research
RS Kent, EM Briggs, BL Colon, C Alvarez, S Silva Pereira, M De Niz
Frontiers in cellular and infection microbiology 12, 900878, 2022
62022
Immunoprecipitation of RNA–DNA hybrid interacting proteins in Trypanosoma brucei reveals conserved and novel activities, including in the control of surface …
MJ Girasol, EM Briggs, CA Marques, JM Batista, D Beraldi, R Burchmore, ...
Nucleic acids research 51 (20), 11123-11141, 2023
52023
Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection. Nat Commun 13: 5752
JF Quintana, P Chandrasegaran, MC Sinton, EM Briggs, TD Otto, ...
52022
Herbicidal compounds
G Mitchell, R Salmon, DP Bacon, IH Aspinall, E Briggs, AJ Avery, ...
Patent WO2009115788 (A1) 24, 2009
52009
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Straipsniai 1–20