X-ray structures of LeuT in substrate-free outward-open and apo inward-open states H Krishnamurthy, E Gouaux Nature 481 (7382), 469-474, 2012 | 559 | 2012 |
Unlocking the molecular secrets of sodium-coupled transporters H Krishnamurthy, CL Piscitelli, E Gouaux Nature 459 (7245), 347-355, 2009 | 382 | 2009 |
Extra-helical binding site of a glucagon receptor antagonist A Jazayeri, AS Doré, D Lamb, H Krishnamurthy, SM Southall, AH Baig, ... Nature 533 (7602), 274-277, 2016 | 228 | 2016 |
Neurotransmitter/sodium symporter orthologue LeuT has a single high-affinity substrate site CL Piscitelli, H Krishnamurthy, E Gouaux Nature 468 (7327), 1129-1132, 2010 | 142 | 2010 |
Associative mechanism for phosphoryl transfer: A molecular dynamics simulation of Escherichia coli adenylate kinase complexed with its substrates H Krishnamurthy, H Lou, A Kimple, C Vieille, RI Cukier Proteins: Structure, Function, and Bioinformatics 58 (1), 88-100, 2005 | 54 | 2005 |
Thermotoga neapolitana adenylate kinase is highly active at 30 degreesC C Vieille, H Krishnamurthy, HH Hyun, A Savchenko, H Yan, JG Zeikus Biochemical Journal 372 (2), 577-585, 2003 | 23 | 2003 |
Dynamics in Thermotoga neapolitana Adenylate Kinase: 15N Relaxation and Hydrogen−Deuterium Exchange Studies of a Hyperthermophilic Enzyme Highly … H Krishnamurthy, K Munro, H Yan, C Vieille Biochemistry 48 (12), 2723-2739, 2009 | 22 | 2009 |
Structural insights on ligand recognition at the human leukotriene B4 receptor 1 N Michaelian, A Sadybekov, É Besserer-Offroy, GW Han, ... Nature communications 12 (1), 2971, 2021 | 18 | 2021 |
Thermostability Mechanisms in Enzymes from Thermotoga neapolitana and Pyrococcus furiosus C Vieille, D Sriprapundh, A Savchenko, S Kang, H Krishnamurth, ... Journal of Microbiology 39 (4), 245-249, 2001 | 2 | 2001 |
Abstract IA013: Discovery of the dual A2A/A2B receptor antagonist MK-1088 for the treatment of solid tumors DE DeMong, S Ranganath, J Cumming, M Larsen, Y Zhang, C Plummer, ... Molecular Cancer Therapeutics 23 (12_Supplement), IA013-IA013, 2024 | | 2024 |
Abstract PR017: Discovery and clinical evaluation of a potent and selective A2A/2B dual receptor antagonist D DeMong, S Ranganath, J Cumming, M Larsen, Y Zhang, C Plummer, ... Molecular Cancer Therapeutics 22 (12_Supplement), PR017-PR017, 2023 | | 2023 |
Structural elucidation of ligand binding sites in family B GPCRs and their application in drug discovery A Jazayeri, A Dore, D Lamb, H Krishnamurthy, S Southall, A Baig, ... ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 72, S24-S24, 2016 | | 2016 |
Analysis of rigidity, stability, and activity in Thermotoga neapolitana adenylate kinase H Krishnamurthy Michigan State University, 2006 | | 2006 |
Testing FIRST predictions on protein stability using adenylate kinase as a model enzyme H Krishnamurthy, AJ Rader, MF Thorpe, LA Kuhn, JG Zeikus, C Vieille Journal of Molecular Graphics and Modelling 18 (4-5), 551, 2000 | | 2000 |