Coronavirus vaccine development: from SARS and MERS to COVID-19 YD Li, WY Chi, JH Su, L Ferrall, CF Hung, TC Wu Journal of biomedical science 27, 1-23, 2020 | 577 | 2020 |
The CDK inhibitor CR8 acts as a molecular glue degrader that depletes cyclin K M Słabicki, Z Kozicka, G Petzold, YD Li, M Manojkumar, RD Bunker, ... Nature 585 (7824), 293-297, 2020 | 328 | 2020 |
COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection WY Chi, YD Li, HC Huang, TEH Chan, SY Chow, JH Su, L Ferrall, ... Journal of biomedical science 29 (1), 82, 2022 | 209 | 2022 |
Template-assisted covalent modification of DCAF16 underlies activity of BRD4 molecular glue degraders YD Li, MW Ma, MM Hassan, M Hunkeler, M Teng, K Puvar, R Lumpkin, ... BioRxiv, 2023 | 41 | 2023 |
Development of PDE6D and CK1α degraders through chemical derivatization of FPFT-2216 M Teng, W Lu, KA Donovan, J Sun, NM Krupnick, RP Nowak, YD Li, ... Journal of medicinal chemistry 65 (1), 747-756, 2021 | 40 | 2021 |
Chemical-free inactivated whole influenza virus vaccine prepared by ultrashort pulsed laser treatment SWD Tsen, N Donthi, V La, WH Hsieh, YD Li, J Knoff, A Chen, TC Wu, ... Journal of biomedical optics 20 (5), 051008-051008, 2015 | 35 | 2015 |
UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability JM Tsai, JD Aguirre, YD Li, J Brown, V Focht, L Kater, G Kempf, ... Molecular cell 83 (15), 2753-2767. e10, 2023 | 30 | 2023 |
PD-1 blockade synergizes with intratumoral vaccination of a therapeutic HPV protein vaccine and elicits regression of tumor in a preclinical model S Peng, M Tan, YD Li, MA Cheng, E Farmer, L Ferrall, S Gaillard, ... Cancer Immunology, Immunotherapy 70, 1049-1062, 2021 | 27 | 2021 |
Chemical specification of E3 ubiquitin ligase engagement by cysteine-reactive chemistry RC Sarott, I You, YD Li, ST Toenjes, KA Donovan, P Seo, M Ordonez, ... Journal of the American Chemical Society 145 (40), 21937-21944, 2023 | 26 | 2023 |
Induced protein degradation for therapeutics: past, present, and future H Yoon, JC Rutter, YD Li, BL Ebert The Journal of Clinical Investigation 134 (1), 2024 | 20 | 2024 |
How SARS-CoV-2 transformed the clinical laboratory: challenges and lessons learned JM Tsai, NV Tolan, AK Petrides, S Kanjilal, M Brigl, NI Lindeman, YD Li, ... The journal of applied laboratory medicine 6 (5), 1338-1354, 2021 | 19 | 2021 |
Exploration of the tunability of BRD4 degradation by DCAF16 trans-labelling covalent glues MM Hassan, YD Li, MW Ma, M Teng, WS Byun, K Puvar, R Lumpkin, ... European Journal of Medicinal Chemistry 279, 116904, 2024 | 14 | 2024 |
Template-assisted covalent modification underlies activity of covalent molecular glues YD Li, MW Ma, MM Hassan, M Hunkeler, M Teng, K Puvar, JC Rutter, ... Nature Chemical Biology, 1-10, 2024 | 13 | 2024 |
The human E3 ligase RNF185 is a regulator of the SARS-CoV-2 envelope protein C Zou, H Yoon, PMC Park, JJ Patten, J Pellman, J Carreiro, JM Tsai, ... Iscience 26 (5), 2023 | 5 | 2023 |
Integration of genomic sequencing drives therapeutic targeting of PDGFRA in T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma J Paolino, B Dimitrov, B Apsel Winger, A Sandoval-Perez, AV Rangarajan, ... Clinical Cancer Research 29 (22), 4613-4626, 2023 | 3 | 2023 |
Outlier expression of isoforms by targeted or total RNA sequencing identifies clinically significant genomic variants in hematolymphoid tumors HK Tsai, T Gogakos, V Lip, JM Tsai, YD Li, AS Fisch, J Weiss, W Yang, ... The Journal of Molecular Diagnostics 25 (9), 665-681, 2023 | 3 | 2023 |
Outlier expression of isoforms by targeted RNA sequencing as clinical markers of genomic variants in B lymphoblastic leukemia and other tumor types HK Tsai, T Gogakos, V Lip, J Tsai, YD Li, A Fisch, J Weiss, L Grimmett, ... medRxiv, 2022.07. 29.22278149, 2022 | 2 | 2022 |
UBR5 Is a Hect E3 Ubiquitin Ligase That Regulates Chromatin Bound Nuclear Hormone Receptor Stability JM Tsai, JD Aguirre, J Brown, V Focht, YD Li, G Kempf, L Kater, P Galli, ... Blood 140 (Supplement 1), 2968-2969, 2022 | 1 | 2022 |
Template-assisted covalent modification of DCAF16 enables BRD4 molecular glue degraders YD Li, MW Ma, MM Hassan, K Puvar, M Teng, B Sandoval, R Lumpkin, ... Cancer Research 83 (7_Supplement), 3424-3424, 2023 | | 2023 |
Discovery of Novel Molecular Glues and Targeted Protein Degradation Mechanisms for Cancer Therapeutics YD Li Harvard University, 2023 | | 2023 |