| Conjugates of γ-Carbolines and Phenothiazine as new selective inhibitors of butyrylcholinesterase and blockers of NMDA receptors for Alzheimer Disease GF Makhaeva, SV Lushchekina, NP Boltneva, VB Sokolov, VV Grigoriev, ... Scientific reports 5 (1), 13164, 2015 | 116 | 2015 |
| New evidence for dual binding site inhibitors of acetylcholinesterase as improved drugs for treatment of Alzheimer's disease I Zueva, J Dias, S Lushchekina, V Semenov, M Mukhamedyarov, ... Neuropharmacology 155, 131-141, 2019 | 90 | 2019 |
| Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment SO Bachurin, EF Shevtsova, GF Makhaeva, VV Grigoriev, NP Boltneva, ... Scientific Reports 7 (1), 45627, 2017 | 86 | 2017 |
| Synthesis, molecular docking and biological evaluation of N, N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors GF Makhaeva, NP Boltneva, SV Lushchekina, OG Serebryakova, ... Bioorganic & Medicinal Chemistry 24 (5), 1050-1062, 2016 | 78 | 2016 |
| Conjugates of tacrine and 1, 2, 4-thiadiazole derivatives as new potential multifunctional agents for Alzheimer’s disease treatment: Synthesis, quantum-chemical … GF Makhaeva, NV Kovaleva, NP Boltneva, SV Lushchekina, ... Bioorganic Chemistry 94, 103387, 2020 | 71 | 2020 |
| Characterization of a complete cycle of acetylcholinesterase catalysis by ab initio QM/MM modeling AV Nemukhin, SV Lushchekina, AV Bochenkova, AA Golubeva, ... Journal of molecular modeling 14, 409-416, 2008 | 71 | 2008 |
| Effects of viscosity and osmotic stress on the reaction of human butyrylcholinesterase with cresyl saligenin phosphate, a toxicant related to aerotoxic syndrome: kinetic and … P Masson, S Lushchekina, LM Schopfer, O Lockridge Biochemical Journal 454 (3), 387-399, 2013 | 70 | 2013 |
| 9-Substituted acridine derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors possessing antioxidant activity for Alzheimer's disease treatment GF Makhaeva, SV Lushchekina, NP Boltneva, OG Serebryakova, ... Bioorganic & medicinal chemistry 25 (21), 5981-5994, 2017 | 62 | 2017 |
| The SOL docking package for computer-aided drug design AN Romanov, FV Grigor'ev, AV Sulimov, SV Lushchekina, YB Martynov, ... Numerical methods and programming 9 (3), 213-233, 2008 | 59* | 2008 |
| Cholinesterase and carboxylesterase inhibitors as pharmacological agents GF Makhaeva, EV Rudakova, NV Kovaleva, SV Lushchekina, ... Russian Chemical Bulletin 68, 967-984, 2019 | 57 | 2019 |
| Optimization of cholinesterase-based catalytic bioscavengers against organophosphorus agents SV Lushchekina, LM Schopfer, BL Grigorenko, AV Nemukhin, ... Frontiers in pharmacology 9, 211, 2018 | 55 | 2018 |
| Emergence of catalytic bioscavengers against organophosphorus agents P Masson, SV Lushchekina Chemico-biological interactions 259, 319-326, 2016 | 55 | 2016 |
| Mixed implicit/explicit solvation models in quantum mechanical calculations of binding enthalpy for protein–ligand complexes E Nikitina, V Sulimov, F Grigoriev, O Kondakova, S Luschekina International journal of quantum chemistry 106 (8), 1943-1963, 2006 | 51 | 2006 |
| Slow-binding inhibition of acetylcholinesterase by an alkylammonium derivative of 6-methyluracil: Mechanism and possible advantages for myasthenia gravis treatment AD Kharlamova, SV Lushchekina, KA Petrov, ED Kots, F Nachon, ... Biochemical Journal 473 (9), 1225-1236, 2016 | 50 | 2016 |
| Esterase profiles of organophosphorus compounds in vitro predict their behavior in vivo GF Makhaeva, EV Rudakova, OG Serebryakova, AY Aksinenko, ... Chemico-Biological Interactions 259, 332-342, 2016 | 47 | 2016 |
| Quantum chemical modelling in the research of molecular mechanisms of enzymatic catalysis AV Nemukhin, BL Grigorenko, SV Lushchekina, SD Varfolomeev Russian Chemical Reviews 81 (11), 1011, 2012 | 47* | 2012 |
| Molecular modeling of mesoscopic composite systems. Structure and micromechanical properties YG Yanovsky, EA Nikitina, YN Karnet, KK Valiev, SV Luschekina PHYSICAL MESOMECHANICS 8 (5/6), 55, 2005 | 47* | 2005 |
| Overview of novel multifunctional agents based on conjugates of γ-carbolines, carbazoles, tetrahydrocarbazoles, phenothiazines, and aminoadamantanes for treatment of Alzheimer … GF Makhaeva, EF Shevtsova, NP Boltneva, SV Lushchekina, ... Chemico-Biological Interactions 308, 224-234, 2019 | 45 | 2019 |
| Focused design of polypharmacophoric neuroprotective compounds: Conjugates of γ-carbolines with carbazole derivatives and tetrahydrocarbazole GF Makhaeva, VB Sokolov, EF Shevtsova, NV Kovaleva, SV Lushchekina, ... Pure and Applied Chemistry 89 (8), 1167-1184, 2017 | 44 | 2017 |
| 6‐Methyluracil Derivatives as Bifunctional Acetylcholinesterase Inhibitors for the Treatment of Alzheimer's Disease VE Semenov, IV Zueva, MA Mukhamedyarov, SV Lushchekina, ... ChemMedChem 10 (11), 1863-1874, 2015 | 44 | 2015 |
Rudy J. RichardsonUniversity of MichiganPatvirtintas el. paštas umich.edu
