| MicroRNAs as regulators, biomarkers and therapeutic targets in liver diseases X Wang, Y He, B Mackowiak, B Gao Gut 70 (4), 784-795, 2021 | 420 | 2021 |
| Mechanisms of xenobiotic receptor activation: Direct vs. indirect B Mackowiak, H Wang Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1859 (9 …, 2016 | 154 | 2016 |
| The roles of xenobiotic receptors: beyond chemical disposition B Mackowiak, J Hodge, S Stern, H Wang Drug Metabolism and Disposition 46 (9), 1361-1371, 2018 | 126 | 2018 |
| Alcohol-associated liver disease B Mackowiak, Y Fu, L Maccioni, B Gao The Journal of clinical investigation 134 (3), 2024 | 99 | 2024 |
| Genome-wide analysis of human constitutive androstane receptor (CAR) transcriptome in wild-type and CAR-knockout HepaRG cells D Li, B Mackowiak, TG Brayman, M Mitchell, L Zhang, SM Huang, H Wang Biochemical pharmacology 98 (1), 190-202, 2015 | 59 | 2015 |
| Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure J Ma, A Guillot, Z Yang, B Mackowiak, S Hwang, O Park, BJ Peiffer, ... The Journal of Clinical Investigation 132 (14), 2022 | 49 | 2022 |
| MicroRNA-223 attenuates hepatocarcinogenesis by blocking hypoxia-driven angiogenesis and immunosuppression Y Fu, B Mackowiak, D Feng, H Lu, Y Guan, T Lehner, H Pan, XW Wang, ... Gut 72 (10), 1942-1958, 2023 | 40 | 2023 |
| Ethanol and its nonoxidative metabolites promote acute liver injury by inducing ER stress, adipocyte death, and lipolysis SH Park, W Seo, MJ Xu, B Mackowiak, Y Lin, Y He, Y Fu, S Hwang, ... Cellular and molecular gastroenterology and hepatology 15 (2), 281-306, 2023 | 39 | 2023 |
| E-selectin-dependent inflammation and lipolysis in adipose tissue exacerbate steatosis-to-NASH progression via S100A8/9 RM Rodrigues, Y He, S Hwang, A Bertola, B Mackowiak, YA Ahmed, ... Cellular and molecular gastroenterology and hepatology 13 (1), 151-171, 2022 | 36 | 2022 |
| Identification of modulators that activate the constitutive androstane receptor from the Tox21 10K compound library C Lynch, B Mackowiak, R Huang, L Li, S Heyward, S Sakamuru, H Wang, ... Toxicological Sciences 167 (1), 282-292, 2019 | 36 | 2019 |
| Mechanistic insights of phenobarbital-mediated activation of human but not mouse pregnane X receptor L Li, MA Welch, Z Li, B Mackowiak, S Heyward, PW Swaan, H Wang Molecular Pharmacology 96 (3), 345-354, 2019 | 31 | 2019 |
| Interleukin-20 exacerbates acute hepatitis and bacterial infection by downregulating IκBζ target genes in hepatocytes Y He, D Feng, S Hwang, B Mackowiak, X Wang, X Xiang, RM Rodrigues, ... Journal of hepatology 75 (1), 163-176, 2021 | 22 | 2021 |
| Hepatic injury and inflammation alter ethanol metabolism and drinking behavior T Ren, B Mackowiak, Y Lin, Y Gao, J Niu, B Gao Food and Chemical Toxicology 136, 111070, 2020 | 20 | 2020 |
| Human constitutive androstane receptor agonist DL5016: A novel sensitizer for cyclophosphamide-based chemotherapies D Liang, L Li, C Lynch, B Mackowiak, WD Hedrich, Y Ai, Y Yin, S Heyward, ... European journal of medicinal chemistry 179, 84-99, 2019 | 16 | 2019 |
| Activation of VIPR1 suppresses hepatocellular carcinoma progression by regulating arginine and pyrimidine metabolism Y Fu, S Liu, RM Rodrigues, Y Han, C Guo, Z Zhu, Y He, B Mackowiak, ... International Journal of Biological Sciences 18 (11), 4341, 2022 | 15 | 2022 |
| Molecular basis of metabolism-mediated conversion of PK11195 from an antagonist to an agonist of the constitutive androstane receptor B Mackowiak, L Li, MA Welch, D Li, JW Jones, S Heyward, MA Kane, ... Molecular Pharmacology 92 (1), 75-87, 2017 | 15 | 2017 |
| Coordinated action of a gut–liver pathway drives alcohol detoxification and consumption Y Fu, B Mackowiak, YH Lin, L Maccioni, T Lehner, H Pan, Y Guan, ... Nature Metabolism 6 (7), 1380-1396, 2024 | 13 | 2024 |
| Alcohol metabolism in alcohol use disorder: a potential therapeutic target T Lehner, B Gao, B Mackowiak Alcohol and Alcoholism 59 (1), agad077, 2024 | 8 | 2024 |
| Mechanistic Analysis of an Extracellular Signal–Regulated Kinase 2–Interacting Compound That Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress R Martinez III, W Huang, R Samadani, B Mackowiak, G Centola, L Chen, ... The Journal of Pharmacology and Experimental Therapeutics 376 (1), 84-97, 2021 | 8 | 2021 |
| High-content analysis of constitutive androstane receptor (CAR) translocation identifies mosapride citrate as a CAR agonist that represses gluconeogenesis B Mackowiak, L Li, C Lynch, A Ziman, S Heyward, M Xia, H Wang Biochemical pharmacology 168, 224-236, 2019 | 8 | 2019 |
