An introduction to spatial transcriptomics for biomedical research CG Williams, HJ Lee, T Asatsuma, R Vento-Tormo, A Haque Genome medicine 14 (1), 68, 2022 | 523 | 2022 |
Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria HJ Lee, A Georgiadou, M Walther, D Nwakanma, LB Stewart, M Levin, ... Science translational medicine 10 (447), eaar3619, 2018 | 126 | 2018 |
Transcriptomic studies of malaria: a paradigm for investigation of systemic host-pathogen interactions HJ Lee, A Georgiadou, TD Otto, M Levin, LJ Coin, DJ Conway, ... Microbiology and Molecular Biology Reviews 82 (2), 10.1128/mmbr. 00071-17, 2018 | 68 | 2018 |
Transcriptome dynamics of CD4+ T cells during malaria maps gradual transit from effector to memory MSF Soon, HJ Lee, JA Engel, J Straube, BS Thomas, CPS Pernold, ... Nature Immunology 21 (12), 1597-1610, 2020 | 57 | 2020 |
A diverse fibroblastic stromal cell landscape in the spleen directs tissue homeostasis and immunity YO Alexandre, D Schienstock, HJ Lee, LC Gandolfo, CG Williams, S Devi, ... Science immunology 7 (67), eabj0641, 2022 | 41 | 2022 |
Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection Z Zhao, H Wang, M Shi, T Zhu, T Pediongco, XY Lim, BS Meehan, ... Nature communications 12 (1), 4355, 2021 | 41 | 2021 |
Development of circulating CD4+ T‐cell memory MSF Soon, JA Engel, HJ Lee, A Haque Immunology and cell biology 97 (7), 617-624, 2019 | 35 | 2019 |
Modelling pathogen load dynamics to elucidate mechanistic determinants of host–Plasmodium falciparum interactions A Georgiadou, HJ Lee, M Walther, AE van Beek, F Fitriani, D Wouters, ... Nature microbiology 4 (9), 1592-1602, 2019 | 26 | 2019 |
Memory CD4+ T cells that co-express PD1 and CTLA4 have reduced response to activating stimuli facilitating HIV latency TA Rasmussen, JM Zerbato, A Rhodes, C Tumpach, A Dantanarayana, ... Cell Reports Medicine 3 (10), 2022 | 21 | 2022 |
Single-cell transcriptomics of allo-reactive CD4+ T cells over time reveals divergent fates during gut GVHD JA Engel, HJ Lee, CG Williams, RD Kuns, S Olver, LI Lansink, MS Soon, ... JCI Insight 5 (13), e137990, 2020 | 13 | 2020 |
Comparative transcriptomic analysis reveals translationally relevant processes in mouse models of malaria A Georgiadou, C Dunican, P Soro-Barrio, HJ Lee, M Kaforou, ... Elife 11, e70763, 2022 | 12 | 2022 |
An introduction to spatial transcriptomics for biomedical research. Genome Med 14 (1): 68 CG Williams, HJ Lee, T Asatsuma, R Vento-Tormo, A Haque | 9 | 2022 |
A diverse fibroblastic stromal cell landscape in the spleen directs tissue homeostasis and immunity. Sci. Immunol. 7, eabj0641 YO Alexandre, D Schienstock, HJ Lee, LC Gandolfo, CG Williams, S Devi, ... | 8 | 2022 |
Plasmodium infection induces phenotypic, clonal, and spatial diversity among differentiating CD4+ T cells CG Williams, ML Moreira, T Asatsuma, HJ Lee, S Li, I Barrera, E Murray, ... Cell reports 43 (6), 2024 | 4 | 2024 |
Systemic host inflammation induces stage-specific transcriptomic modification and slower maturation in malaria parasites LIM Lansink, OP Skinner, JA Engel, HJ Lee, MSF Soon, CG Williams, ... Mbio 14 (4), e01129-23, 2023 | 2 | 2023 |
MAIT cell plasticity enables functional adaptation that drives antibacterial immune protection H Wang, MNT Souter, M de Lima Moreira, S Li, Y Zhou, AG Nelson, J Yu, ... Science Immunology 9 (102), eadp9841, 2024 | 1 | 2024 |
CD4+ T cells display a spectrum of recall dynamics during re-infection with malaria parasites HJ Lee, ML Moreira, S Li, T Asatsuma, CG Williams, OP Skinner, S Asad, ... Nature Communications 15 (1), 5497, 2024 | 1 | 2024 |
Spatial transcriptomics maps molecular and cellular requirements for CD4+ T cell-dependent immunity to malaria CG Williams, ML Moreira, T Asatsuma, OP Skinner, HJ Lee, S Li, I Barrera, ... bioRxiv, 2023.02. 23.529309, 2023 | 1 | 2023 |
Deconvoluting TCR-dependent & -independent activation is vital for reliable Ag-specific CD4+ T cell characterization by AIM assay MZM Zheng, L Burmas, HX Tan, MC Trieu, HJ Lee, D Rawlinson, ... bioRxiv, 2024.12. 10.627643, 2024 | | 2024 |
Temporally overlapping mechanisms diversify clonal B cell responses in vivo. OP Skinner, S Asad, ML Moreira, HJ Lee, CG Williams, S Li, W Jin, ... bioRxiv, 2024.12. 17.628863, 2024 | | 2024 |