| Adeno-associated virus vector as a platform for gene therapy delivery D Wang, PWL Tai, G Gao Nature reviews Drug discovery 18 (5), 358-378, 2019 | 2216 | 2019 |
| Viral vector platforms within the gene therapy landscape JT Bulcha, Y Wang, H Ma, PWL Tai, G Gao Signal transduction and targeted therapy 6 (1), 53, 2021 | 1161 | 2021 |
| Design of tissue-specific regulatory cassettes for high-level rAAV-mediated expression in skeletal and cardiac muscle MZ Salva, CL Himeda, PWL Tai, E Nishiuchi, P Gregorevic, JM Allen, ... Molecular Therapy 15 (2), 320-329, 2007 | 261 | 2007 |
| Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses YK Chan, SK Wang, CJ Chu, DA Copland, AJ Letizia, H Costa Verdera, ... Science translational medicine 13 (580), eabd3438, 2021 | 182 | 2021 |
| Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis H Wu, TW Whitfield, JAR Gordon, JR Dobson, PWL Tai, AJ van Wijnen, ... Genome biology 15, 1-17, 2014 | 155 | 2014 |
| Overcoming innate immune barriers that impede AAV gene therapy vectors M Muhuri, Y Maeda, H Ma, S Ram, KA Fitzgerald, PWL Tai, G Gao The Journal of clinical investigation 131 (1), 2021 | 149 | 2021 |
| Short DNA hairpins compromise recombinant adeno-associated virus genome homogeneity J Xie, Q Mao, PWL Tai, R He, J Ai, Q Su, Y Zhu, H Ma, J Li, S Gong, ... Molecular Therapy 25 (6), 1363-1374, 2017 | 138 | 2017 |
| Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis YS Yang, J Xie, D Wang, JM Kim, PWL Tai, E Gravallese, G Gao, JH Shim Nature communications 10 (1), 2958, 2019 | 114 | 2019 |
| A safe and reliable technique for CNS delivery of AAV vectors in the cisterna magna T Taghian, MG Marosfoi, AS Puri, OI Cataltepe, RM King, EB Diffie, ... Molecular Therapy 28 (2), 411-421, 2020 | 100 | 2020 |
| AAV gene therapy for Tay-Sachs disease TR Flotte, O Cataltepe, A Puri, AR Batista, R Moser, D McKenna-Yasek, ... Nature medicine 28 (2), 251-259, 2022 | 97 | 2022 |
| Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adeno-associated viruses Y Yoon, D Wang, PWL Tai, J Riley, G Gao, JA Rivera-Pérez Nature communications 9 (1), 1-12, 2018 | 94 | 2018 |
| Adeno-associated virus genome population sequencing achieves full vector genome resolution and reveals human-vector chimeras PWL Tai, J Xie, K Fong, M Seetin, C Heiner, Q Su, M Weiand, D Wilmot, ... Molecular Therapy Methods & Clinical Development 9, 130-141, 2018 | 88 | 2018 |
| Self-inactivating, all-in-one AAV vectors for precision Cas9 genome editing via homology-directed repair in vivo R Ibraheim, PWL Tai, A Mir, N Javeed, J Wang, TC Rodríguez, ... Nature communications 12 (1), 6267, 2021 | 84 | 2021 |
| Chromatin dynamics regulate mesenchymal stem cell lineage specification and differentiation to osteogenesis H Wu, JAR Gordon, TW Whitfield, PWL Tai, AJ van Wijnen, JL Stein, ... Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1860 (4), 438-449, 2017 | 69 | 2017 |
| AAV-genome population sequencing of vectors packaging CRISPR components reveals design-influenced heterogeneity NT Tran, C Heiner, K Weber, M Weiand, D Wilmot, J Xie, D Wang, ... Molecular Therapy Methods & Clinical Development 18, 639-651, 2020 | 61 | 2020 |
| Human and insect cell-produced recombinant adeno-associated viruses show differences in genome heterogeneity NT Tran, E Lecomte, S Saleun, S Namkung, C Robin, K Weber, E Devine, ... Human Gene Therapy 33 (7-8), 371-388, 2022 | 57 | 2022 |
| A scalable and accurate method for quantifying vector genomes of recombinant adeno-associated viruses in crude lysate J Ai, R Ibraheim, PWL Tai, G Gao Human gene therapy methods 28 (3), 139-147, 2017 | 54 | 2017 |
| Structural characterization of a novel human adeno-associated virus capsid with neurotropic properties HL Hsu, A Brown, AB Loveland, A Lotun, M Xu, L Luo, G Xu, J Li, L Ren, ... Nature communications 11 (1), 3279, 2020 | 51 | 2020 |
| Bone-targeting AAV-mediated gene silencing in osteoclasts for osteoporosis therapy YS Yang, J Xie, S Chaugule, D Wang, JM Kim, JH Kim, PWL Tai, S Seo, ... Molecular Therapy Methods & Clinical Development 17, 922-935, 2020 | 50 | 2020 |
| Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice D Wang, J Li, CQ Song, K Tran, H Mou, PH Wu, PWL Tai, CA Mendonca, ... Nature biotechnology 36 (9), 839-842, 2018 | 50 | 2018 |
