Structure and function of SET and MYND domain-containing proteins N Spellmon, J Holcomb, L Trescott, N Sirinupong, Z Yang International journal of molecular sciences 16 (1), 1406-1428, 2015 | 174 | 2015 |
Structural insights into estrogen receptor α methylation by histone methyltransferase SMYD2, a cellular event implicated in estrogen signaling regulation Y Jiang, L Trescott, J Holcomb, X Zhang, J Brunzelle, N Sirinupong, X Shi, ... Journal of molecular biology 426 (20), 3413-3425, 2014 | 72 | 2014 |
Protein crystallization: Eluding the bottleneck of X-ray crystallography J Holcomb, N Spellmon, Y Zhang, M Doughan, C Li, Z Yang AIMS biophysics 4 (4), 557, 2017 | 64 | 2017 |
SMYD2 glutathionylation contributes to degradation of sarcomeric proteins DNP Munkanatta Godage, GC VanHecke, KTG Samarasinghe, HZ Feng, ... Nature communications 9 (1), 4341, 2018 | 39 | 2018 |
Increased activity of unlinked Zika virus NS2B/NS3 protease compared to linked Zika virus protease BD Kuiper, K Slater, N Spellmon, J Holcomb, P Medapureddy, ... Biochemical and biophysical research communications 492 (4), 668-673, 2017 | 33 | 2017 |
A critical role of CXCR2 PDZ-mediated interactions in endothelial progenitor cell homing and angiogenesis Y Hou, Y Wu, SM Farooq, X Guan, S Wang, Y Liu, JJ Oblak, J Holcomb, ... Stem cell research 14 (2), 133-143, 2015 | 27 | 2015 |
Crystallographic analysis of NHERF1–PLCβ3 interaction provides structural basis for CXCR2 signaling in pancreatic cancer Y Jiang, S Wang, J Holcomb, L Trescott, X Guan, Y Hou, J Brunzelle, ... Biochemical and biophysical research communications 446 (2), 638-643, 2014 | 26 | 2014 |
Structural insights into PDZ-mediated interaction of NHERF2 and LPA2, a cellular event implicated in CFTR channel regulation J Holcomb, Y Jiang, G Lu, L Trescott, J Brunzelle, N Sirinupong, C Li, ... Biochemical and biophysical research communications 446 (1), 399-403, 2014 | 17 | 2014 |
Crystal structure of the NHERF1 PDZ2 domain in complex with the chemokine receptor CXCR2 reveals probable modes of PDZ2 dimerization J Holcomb, Y Jiang, X Guan, L Trescott, G Lu, Y Hou, S Wang, J Brunzelle, ... Biochemical and biophysical research communications 448 (2), 169-174, 2014 | 16 | 2014 |
PDZ structure and implication in selective drug design against cystic fibrosis J Holcomb, N Spellmon, L Trescott, F Sun, C Li, Z Yang Current drug targets 16 (9), 945-950, 2015 | 11 | 2015 |
Purification of histone lysine methyltransferase SMYD2 and co-crystallization with a target peptide from estrogen receptor α Y Jiang, J Holcomb, N Spellmon, Z Yang Estrogen Receptors: Methods and Protocols, 207-217, 2016 | 9 | 2016 |
SAXS analysis of a soluble cytosolic NgBR construct including extracellular and transmembrane domains J Holcomb, M Doughan, N Spellmon, B Lewis, E Perry, Y Zhang, L Nico, ... PLoS One 13 (1), e0191371, 2018 | 8 | 2018 |
New open conformation of SMYD3 implicates conformational selection and allostery N Spellmon, X Sun, W Xue, J Holcomb, S Chakravarthy, W Shang, ... AIMS biophysics 4 (1), 1, 2016 | 8 | 2016 |
Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF N Spellmon, J Holcomb, A Niu, V Choudhary, X Sun, Y Zhang, J Wan, ... Biochemical and biophysical research communications 485 (2), 529-534, 2017 | 6 | 2017 |
Expression, Purification and Characterization of a GII. 4 Norovirus Protease from Minerva Virus BD Kuiper, KM Muzzarelli, BJ Keusch, J Holcomb, F Amblard, P Liu, ... Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious …, 2018 | 3 | 2018 |
SMYD2 structure and function: a multispecificity protein lysine methyltransferase M Rice, Y Jiang, J Holcomb, L Trescott, N Spellmon, N Sirinupong, ... J. Cytol. Molecul. Biol 1 (7), 2014 | 2 | 2014 |
Targeting the Root Cause of Cystic Fibrosis. L Trescott, J Holcomb, N Spellmon, C Mcleod, L Aljehane, F Sun, C Li, ... Current Drug Targets 16 (9), 933-944, 2015 | 1 | 2015 |
Targeting the Root Cause of Cystic Fibrosis L Trescott, J Holcomb, N Spellmon, C Mcleod, L Aljehane, F Sun, C Li, ... Curr Drug Targets 15, 15, 2014 | 1 | 2014 |
Complex structure of the disulfide bond‐dimerized PDZ‐RhoGEF and CXCR2 PDZ‐binding motif: A new mode of PDZ dimerization NS Spellmon, J Holcomb, A Niu, V Choudhary, J Brunzelle, C Li, Z Yang The FASEB Journal 31, 761.21-761.21, 2017 | | 2017 |
Solution Structure of the Transmembrane Nogo‐B Receptor and Insight into its Topological Orientation by Small Angle X‐ray Scattering Analysis J Holcomb, N Spellmon, W Shang, Q Miao, Z Yang The FASEB Journal 31, 603.9-603.9, 2017 | | 2017 |