Stebėti
Joshua Holcomb
Joshua Holcomb
Nežinomas ryšys
Patvirtintas el. paštas cmich.edu
Pavadinimas
Cituota
Cituota
Metai
Structure and function of SET and MYND domain-containing proteins
N Spellmon, J Holcomb, L Trescott, N Sirinupong, Z Yang
International journal of molecular sciences 16 (1), 1406-1428, 2015
1742015
Structural insights into estrogen receptor α methylation by histone methyltransferase SMYD2, a cellular event implicated in estrogen signaling regulation
Y Jiang, L Trescott, J Holcomb, X Zhang, J Brunzelle, N Sirinupong, X Shi, ...
Journal of molecular biology 426 (20), 3413-3425, 2014
722014
Protein crystallization: Eluding the bottleneck of X-ray crystallography
J Holcomb, N Spellmon, Y Zhang, M Doughan, C Li, Z Yang
AIMS biophysics 4 (4), 557, 2017
642017
SMYD2 glutathionylation contributes to degradation of sarcomeric proteins
DNP Munkanatta Godage, GC VanHecke, KTG Samarasinghe, HZ Feng, ...
Nature communications 9 (1), 4341, 2018
392018
Increased activity of unlinked Zika virus NS2B/NS3 protease compared to linked Zika virus protease
BD Kuiper, K Slater, N Spellmon, J Holcomb, P Medapureddy, ...
Biochemical and biophysical research communications 492 (4), 668-673, 2017
332017
A critical role of CXCR2 PDZ-mediated interactions in endothelial progenitor cell homing and angiogenesis
Y Hou, Y Wu, SM Farooq, X Guan, S Wang, Y Liu, JJ Oblak, J Holcomb, ...
Stem cell research 14 (2), 133-143, 2015
272015
Crystallographic analysis of NHERF1–PLCβ3 interaction provides structural basis for CXCR2 signaling in pancreatic cancer
Y Jiang, S Wang, J Holcomb, L Trescott, X Guan, Y Hou, J Brunzelle, ...
Biochemical and biophysical research communications 446 (2), 638-643, 2014
262014
Structural insights into PDZ-mediated interaction of NHERF2 and LPA2, a cellular event implicated in CFTR channel regulation
J Holcomb, Y Jiang, G Lu, L Trescott, J Brunzelle, N Sirinupong, C Li, ...
Biochemical and biophysical research communications 446 (1), 399-403, 2014
172014
Crystal structure of the NHERF1 PDZ2 domain in complex with the chemokine receptor CXCR2 reveals probable modes of PDZ2 dimerization
J Holcomb, Y Jiang, X Guan, L Trescott, G Lu, Y Hou, S Wang, J Brunzelle, ...
Biochemical and biophysical research communications 448 (2), 169-174, 2014
162014
PDZ structure and implication in selective drug design against cystic fibrosis
J Holcomb, N Spellmon, L Trescott, F Sun, C Li, Z Yang
Current drug targets 16 (9), 945-950, 2015
112015
Purification of histone lysine methyltransferase SMYD2 and co-crystallization with a target peptide from estrogen receptor α
Y Jiang, J Holcomb, N Spellmon, Z Yang
Estrogen Receptors: Methods and Protocols, 207-217, 2016
92016
SAXS analysis of a soluble cytosolic NgBR construct including extracellular and transmembrane domains
J Holcomb, M Doughan, N Spellmon, B Lewis, E Perry, Y Zhang, L Nico, ...
PLoS One 13 (1), e0191371, 2018
82018
New open conformation of SMYD3 implicates conformational selection and allostery
N Spellmon, X Sun, W Xue, J Holcomb, S Chakravarthy, W Shang, ...
AIMS biophysics 4 (1), 1, 2016
82016
Structural basis of PDZ-mediated chemokine receptor CXCR2 scaffolding by guanine nucleotide exchange factor PDZ-RhoGEF
N Spellmon, J Holcomb, A Niu, V Choudhary, X Sun, Y Zhang, J Wan, ...
Biochemical and biophysical research communications 485 (2), 529-534, 2017
62017
Expression, Purification and Characterization of a GII. 4 Norovirus Protease from Minerva Virus
BD Kuiper, KM Muzzarelli, BJ Keusch, J Holcomb, F Amblard, P Liu, ...
Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious …, 2018
32018
SMYD2 structure and function: a multispecificity protein lysine methyltransferase
M Rice, Y Jiang, J Holcomb, L Trescott, N Spellmon, N Sirinupong, ...
J. Cytol. Molecul. Biol 1 (7), 2014
22014
Targeting the Root Cause of Cystic Fibrosis.
L Trescott, J Holcomb, N Spellmon, C Mcleod, L Aljehane, F Sun, C Li, ...
Current Drug Targets 16 (9), 933-944, 2015
12015
Targeting the Root Cause of Cystic Fibrosis
L Trescott, J Holcomb, N Spellmon, C Mcleod, L Aljehane, F Sun, C Li, ...
Curr Drug Targets 15, 15, 2014
12014
Complex structure of the disulfide bond‐dimerized PDZ‐RhoGEF and CXCR2 PDZ‐binding motif: A new mode of PDZ dimerization
NS Spellmon, J Holcomb, A Niu, V Choudhary, J Brunzelle, C Li, Z Yang
The FASEB Journal 31, 761.21-761.21, 2017
2017
Solution Structure of the Transmembrane Nogo‐B Receptor and Insight into its Topological Orientation by Small Angle X‐ray Scattering Analysis
J Holcomb, N Spellmon, W Shang, Q Miao, Z Yang
The FASEB Journal 31, 603.9-603.9, 2017
2017
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Straipsniai 1–20