| Oxidative stress and epigenetic modifications in the pathogenesis of diabetic retinopathy RA Kowluru, A Kowluru, M Mishra, B Kumar Progress in retinal and eye research 48, 40-61, 2015 | 337 | 2015 |
| Small G proteins in islet β-cell function A Kowluru Endocrine reviews 31 (1), 52-78, 2010 | 154 | 2010 |
| TIAM1–RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy RA Kowluru, A Kowluru, R Veluthakal, G Mohammad, I Syed, JM Santos, ... Diabetologia 57, 1047-1056, 2014 | 147 | 2014 |
| Modulation of insulin secretion from normal rat islets by inhibitors of the post-translational modifications of GTP-binding proteins SA Metz, ME Rabaglia, JB Stock, A Kowluru Biochemical Journal 295 (1), 31-40, 1993 | 146 | 1993 |
| Glucose-and GTP-dependent stimulation of the carboxyl methylation of CDC42 in rodent and human pancreatic islets and pure beta cells. Evidence for an essential role of GTP … A Kowluru, SE Seavey, G Li, RL Sorenson, AJ Weinhaus, R Nesher, ... The Journal of clinical investigation 98 (2), 540-555, 1996 | 136 | 1996 |
| Reversible sodium pump defect and swelling in the diabetic rat erythrocyte: effects on filterability and implications for microangiopathy. R Kowluru, MW Bitensky, A Kowluru, M Dembo, PA Keaton, T Buican Proceedings of the National Academy of Sciences 86 (9), 3327-3331, 1989 | 132 | 1989 |
| Increased phagocyte-like NADPH oxidase and ROS generation in type 2 diabetic ZDF rat and human islets: role of Rac1–JNK1/2 signaling pathway in mitochondrial dysregulation in … I Syed, CN Kyathanahalli, B Jayaram, S Govind, CJ Rhodes, RA Kowluru, ... Diabetes 60 (11), 2843-2852, 2011 | 128 | 2011 |
| Localization and characterization of the mitochondrial isoform of the nucleoside diphosphate kinase in the pancreatic β cell: evidence for its complexation with mitochondrial … A Kowluru, M Tannous, HQ Chen Archives of biochemistry and biophysics 398 (2), 160-169, 2002 | 128 | 2002 |
| Novel regulation by Rac1 of glucose-and forskolin-induced insulin secretion in INS-1 β-cells J Li, R Luo, A Kowluru, GD Li American Journal of Physiology-Endocrinology and Metabolism 286 (5), E818-E827, 2004 | 124 | 2004 |
| The stimulus-secretion coupling of glucose-induced insulin release XLVI. Physiological role of L-glutamine as a fuel for pancreatic islets WJ Malaisse, A Sener, AR Carpinelli, K Anjaneyulu, P Lebrun, ... Molecular and cellular endocrinology 20 (2), 171-189, 1980 | 124 | 1980 |
| A novel regulatory mechanism for trimeric GTP-binding proteins in the membrane and secretory granule fractions of human and rodent β cells A KOWLURU, SE SEAVEY, CJ RHODES, SA METZ Biochemical Journal 313 (1), 97-107, 1996 | 118 | 1996 |
| Evidence for differential roles of the Rho subfamily of GTP-binding proteins in glucose-and calcium-induced insulin secretion from pancreatic β cells A Kowluru, G Li, ME Rabaglia, VB Segu, F Hofmann, K Aktories, SA Metz Biochemical pharmacology 54 (10), 1097-1108, 1997 | 110 | 1997 |
| Epigenetics and regulation of oxidative stress in diabetic retinopathy AJ Duraisamy, M Mishra, A Kowluru, RA Kowluru Investigative ophthalmology & visual science 59 (12), 4831-4840, 2018 | 91 | 2018 |
| Carboxylmethylation of the catalytic subunit of protein phosphatase 2A in insulin-secreting cells: evidence for functional consequences on enzyme activity and insulin secretion A Kowluru, SE Seavey, ME Rabaglia, R Nesher, SA Metz Endocrinology 137 (6), 2315-2323, 1996 | 91 | 1996 |
| Activation of acetyl-CoA carboxylase by a glutamate-and magnesium-sensitive protein phosphatase in the islet β-cell A Kowluru, HQ Chen, LM Modrick, C Stefanelli Diabetes 50 (7), 1580-1587, 2001 | 89 | 2001 |
| Hyperactivation of protein phosphatase 2A in models of glucolipotoxicity and diabetes: potential mechanisms and functional consequences A Kowluru, A Matti Biochemical pharmacology 84 (5), 591-597, 2012 | 88 | 2012 |
| Regulation of insulin secretion and reactive oxygen species production by free fatty acids in pancreatic islets MF Graciano, M Valle, A Kowluru, R Curi, A Carpinelli Islets 3 (5), 213-223, 2011 | 87 | 2011 |
| Hyperlipidemia and the development of diabetic retinopathy: Comparison between type 1 and type 2 animal models RA Kowluru, M Mishra, A Kowluru, B Kumar Metabolism 65 (10), 1570-1581, 2016 | 86 | 2016 |
| The regulatory roles of mitogen-activated protein kinase (MAPK) pathways in health and diabetes: lessons learned from the pancreatic β-cell V Sidarala, A Kowluru Recent patents on endocrine, metabolic & immune drug discovery 10 (2), 76-84, 2016 | 82 | 2016 |
| Lipotoxicity augments glucotoxicity-induced mitochondrial damage in the development of diabetic retinopathy B Kumar, A Kowluru, RA Kowluru Investigative ophthalmology & visual science 56 (5), 2985-2992, 2015 | 80 | 2015 |
Renu KowluruWayne State UniversityPatvirtintas el. paštas med.wayne.edu
