Disease modeling using 3D organoids derived from human induced pluripotent stem cells BX Ho, NMQ Pek, BS Soh International journal of molecular sciences 19 (4), 936, 2018 | 175 | 2018 |
Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy JH Hor, ESY Soh, LY Tan, VJW Lim, MM Santosa, null Winanto, BX Ho, ... Cell death & disease 9 (11), 1100, 2018 | 98 | 2018 |
In vivo genome editing as a therapeutic approach BX Ho, SJH Loh, WK Chan, BS Soh International journal of molecular sciences 19 (9), 2721, 2018 | 85 | 2018 |
ALS motor neurons exhibit hallmark metabolic defects that are rescued by SIRT3 activation JH Hor, MM Santosa, VJW Lim, BX Ho, A Taylor, ZJ Khong, J Ravits, ... Cell Death & Differentiation 28 (4), 1379-1397, 2021 | 77 | 2021 |
Mending a broken heart: current strategies and limitations of cell-based therapy LC Liew, BX Ho, BS Soh Stem Cell Research & Therapy 11, 1-15, 2020 | 76 | 2020 |
Wnt/β-catenin-mediated signaling re-activates proliferation of matured cardiomyocytes Y Fan, BX Ho, JKS Pang, NMQ Pek, JH Hor, SY Ng, BS Soh Stem Cell Research & Therapy 9, 1-13, 2018 | 74 | 2018 |
Mitochondrial 3243A> G mutation confers pro-atherogenic and pro-inflammatory properties in MELAS iPS derived endothelial cells NMQ Pek, QH Phua, BX Ho, JKS Pang, JH Hor, O An, HH Yang, Y Yu, ... Cell Death & Disease 10 (11), 802, 2019 | 38 | 2019 |
Robust generation of human-chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases BX Ho, JKS Pang, Y Chen, YH Loh, O An, HH Yang, VP Seshachalam, ... Stem Cell Research & Therapy 13 (1), 529, 2022 | 24 | 2022 |
Insights to heart development and cardiac disease models using pluripotent stem cell derived 3D organoids JKS Pang, BX Ho, WK Chan, BS Soh Frontiers in Cell and Developmental Biology 9, 788955, 2021 | 12 | 2021 |
Upregulation of the JAK-STAT pathway promotes maturation of human embryonic stem cell-derived cardiomyocytes BX Ho, H Yu, JKS Pang, JH Hor, LC Liew, P Szyniarowski, CYY Lim, O An, ... Stem cell reports 16 (12), 2928-2941, 2021 | 4 | 2021 |
Compressible hollow microlasers in organoids for high-throughput and real-time mechanical screening G Fang, BX Ho, H Xu, C Gong, Z Qiao, Y Liao, S Zhu, H Lu, N Nie, T Zhou, ... ACS nano 18 (38), 26338-26349, 2024 | 1 | 2024 |
JAK2 as a surface marker for enrichment of human pluripotent stem cells-derived ventricular cardiomyocytes LC Liew, BM Poh, O An, BX Ho, CYY Lim, JKS Pang, LY Beh, HH Yang, ... Stem Cell Research & Therapy 14 (1), 367, 2023 | 1 | 2023 |
Generation of human chambered cardiac organoids from pluripotent stem cells for improved modelling of cardiovascular diseases BX Ho, JK Sheng Pang, QH Phua, LC Liew, BM Poh, Y Chen, YH Loh, ... bioRxiv, 2021.05. 21.445153, 2021 | 1 | 2021 |
ALS Motor Neurons Exhibit Hallmark Metabolic Defects That Are Rescued by Nicotinamide and SIRT3 Activation JH Hor, MM Santosa, VJW Lim, B Xuan Ho, A Taylor, ZJ Khong, J Ravits, ... bioRxiv, 713651, 2019 | 1 | 2019 |