| gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis J Bollrath, TJ Phesse, VA von Burstin, T Putoczki, M Bennecke, ... Cancer cell 15 (2), 91-102, 2009 | 1124 | 2009 |
| Myc deletion rescues Apc deficiency in the small intestine OJ Sansom, VS Meniel, V Muncan, TJ Phesse, JA Wilkins, KR Reed, ... Nature 446 (7136), 676-679, 2007 | 704 | 2007 |
| RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis JA Rickard, JA O’Donnell, JM Evans, N Lalaoui, AR Poh, TW Rogers, ... Cell 157 (5), 1175-1188, 2014 | 623 | 2014 |
| Rapid loss of intestinal crypts upon conditional deletion of the Wnt/Tcf-4 target gene c-Myc V Muncan, OJ Sansom, L Tertoolen, TJ Phesse, H Begthel, E Sancho, ... Molecular and cellular biology, 2006 | 310 | 2006 |
| Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling GH Ashton, JP Morton, K Myant, TJ Phesse, RA Ridgway, V Marsh, ... Developmental cell 19 (2), 259-269, 2010 | 209 | 2010 |
| Liver zonation occurs through a β-catenin–dependent, c-Myc–independent mechanism ZD Burke, KR Reed, TJ Phesse, OJ Sansom, AR Clarke, D Tosh Gastroenterology 136 (7), 2316-2324. e3, 2009 | 189 | 2009 |
| IL-33-mediated mast cell activation promotes gastric cancer through macrophage mobilization MF Eissmann, C Dijkstra, A Jarnicki, T Phesse, J Brunnberg, AR Poh, ... Nature communications 10 (1), 2735, 2019 | 183 | 2019 |
| Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5+ stem cells DJ Flanagan, TJ Phesse, N Barker, RHM Schwab, N Amin, J Malaterre, ... Stem cell reports 4 (5), 759-767, 2015 | 161 | 2015 |
| Endogenous c-Myc is essential for p53-induced apoptosis in response to DNA damage in vivo TJ Phesse, KB Myant, AM Cole, RA Ridgway, H Pearson, V Muncan, ... Cell Death & Differentiation 21 (6), 956-966, 2014 | 127 | 2014 |
| Mesenchymal niche-derived neuregulin-1 drives intestinal stem cell proliferation and regeneration of damaged epithelium T Jardé, WH Chan, FJ Rossello, TK Kahlon, M Theocharous, TK Arackal, ... Cell stem cell 27 (4), 646-662. e7, 2020 | 125 | 2020 |
| Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth HB Pearson, J Li, VS Meniel, CM Fennell, P Waring, KG Montgomery, ... Cancer discovery 8 (6), 764-779, 2018 | 113 | 2018 |
| PHLDA1 expression marks the putative epithelial stem cells and contributes to intestinal tumorigenesis A Sakthianandeswaren, M Christie, C D'Andreti, C Tsui, RN Jorissen, S Li, ... Cancer Research 71 (10), 3709-3719, 2011 | 105 | 2011 |
| Wnt signalling in gastrointestinal epithelial stem cells DJ Flanagan, CR Austin, E Vincan, TJ Phesse Genes 9 (4), 178, 2018 | 103 | 2018 |
| Dual targeting of bromodomain and extraterminal domain proteins, and WNT or MAPK signaling, inhibits c-MYC expression and proliferation of colorectal cancer cells L Tögel, R Nightingale, AC Chueh, A Jayachandran, H Tran, T Phesse, ... Molecular cancer therapeutics 15 (6), 1217-1226, 2016 | 99 | 2016 |
| K-ras and Wnt signaling synergize to accelerate prostate tumorigenesis in the mouse HB Pearson, TJ Phesse, AR Clarke Cancer research 69 (1), 94-101, 2009 | 97 | 2009 |
| Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations DJ Flanagan, N Barker, NSD Costanzo, EA Mason, A Gurney, VS Meniel, ... Cancer Research 79 (5), 970-981, 2019 | 95 | 2019 |
| Frizzled7: a promising Achilles’ heel for targeting the Wnt receptor complex to treat cancer T Phesse, D Flanagan, E Vincan Cancers 8 (5), 50, 2016 | 85 | 2016 |
| Partial inhibition of gp130-Jak-Stat3 signaling prevents Wnt–β-catenin–mediated intestinal tumor growth and regeneration TJ Phesse, M Buchert, E Stuart, DJ Flanagan, M Faux, S Afshar-Sterle, ... Science signaling 7 (345), ra92-ra92, 2014 | 79 | 2014 |
| Targeting Wnt signaling for the treatment of gastric cancer S Koushyar, AG Powell, E Vincan, TJ Phesse International Journal of Molecular Sciences 21 (11), 3927, 2020 | 76 | 2020 |
| Wnt signaling in cancer: not a binary ON: OFF switch DJ Flanagan, E Vincan, TJ Phesse Cancer research 79 (23), 5901-5906, 2019 | 67 | 2019 |