Microhomology-mediated end joining is the principal mediator of double-strand break repair during mitochondrial DNA lesions SK Tadi, R Sebastian, S Dahal, RK Babu, B Choudhary, SC Raghavan Molecular biology of the cell 27 (2), 223-235, 2016 | 135 | 2016 |
SCLC-CellMiner: a resource for small cell lung cancer cell line genomics and pharmacology based on genomic signatures C Tlemsani, L Pongor, F Elloumi, L Girard, KE Huffman, N Roper, ... Cell reports 33 (3), 2020 | 126 | 2020 |
Replication stress shapes a protective chromatin environment across fragile genomic regions J Kim, D Sturgill, R Sebastian, S Khurana, AD Tran, GB Edwards, ... Molecular cell 69 (1), 36-47. e7, 2018 | 101 | 2018 |
Induction of DNA damage and erroneous repair can explain genomic instability caused by endosulfan R Sebastian, SC Raghavan Carcinogenesis 37 (10), 929-940, 2016 | 56 | 2016 |
Time-dependent predominance of nonhomologous DNA end-joining pathways during embryonic development in mice KK Chiruvella, R Sebastian, S Sharma, AA Karande, B Choudhary, ... Journal of molecular biology 417 (3), 197-211, 2012 | 53 | 2012 |
Epigenetic regulation of DNA repair pathway choice by MacroH2A1 splice variants ensures genome stability R Sebastian, EK Hosogane, EG Sun, AD Tran, WC Reinhold, S Burkett, ... Molecular cell 79 (5), 836-845. e7, 2020 | 43 | 2020 |
Transcription-associated events affecting genomic integrity R Sebastian, P Oberdoerffer Philosophical Transactions of the Royal Society B: Biological Sciences 372 …, 2017 | 36 | 2017 |
Exposure to Endosulfan can result in male infertility due to testicular atrophy and reduced sperm count R Sebastian, SC Raghavan Cell death discovery 1 (1), 1-10, 2015 | 34 | 2015 |
Dynamics of replication origin over-activation H Fu, CE Redon, BL Thakur, K Utani, R Sebastian, SM Jang, JM Gross, ... Nature Communications 12 (1), 3448, 2021 | 33 | 2021 |
Exposure to welding fumes activates DNA damage response and redox-sensitive transcription factor signalling in Sprague-Dawley rats J Krishnaraj, J Kowshik, R Sebastian, SC Raghavan, S Nagini Toxicology letters 274, 8-19, 2017 | 21 | 2017 |
ATR inhibition augments the efficacy of lurbinectedin in small‐cell lung cancer CW Schultz, Y Zhang, R Elmeskini, A Zimmermann, H Fu, Y Murai, ... EMBO Molecular Medicine 15 (8), e17313, 2023 | 19 | 2023 |
Convergence of SIRT1 and ATR signaling to modulate replication origin dormancy BL Thakur, AM Baris, H Fu, CE Redon, LS Pongor, S Mosavarpour, ... Nucleic acids research 50 (9), 5111-5128, 2022 | 19 | 2022 |
Endosulfan induces male infertility R Sebastian, SC Raghavan Cell death & disease 6 (12), e2022, 2015 | 18 | 2015 |
Molecular mechanism of Endosulfan action in mammals R Sebastian, SC Raghavan Journal of biosciences 42, 149-153, 2017 | 14 | 2017 |
Microenvironment shapes small-cell lung cancer neuroendocrine states and presents therapeutic opportunities P Desai, N Takahashi, R Kumar, S Nichols, J Malin, A Hunt, C Schultz, ... Cell Reports Medicine 5 (6), 2024 | 6 | 2024 |
Encounters in three dimensions: how nuclear topology shapes genome integrity R Sebastian, MI Aladjem, P Oberdoerffer Frontiers in Genetics 12, 746380, 2021 | 6 | 2021 |
Acetalax (Oxyphenisatin Acetate, NSC 59687) and Bisacodyl Cause Oncosis in Triple-Negative Breast Cancer Cell Lines by Poisoning the Ion Exchange Membrane Protein TRPM4 M Mizunuma, CE Redon, LK Saha, AD Tran, A Dhall, R Sebastian, ... Cancer Research Communications 4 (8), 2101-2111, 2024 | 3 | 2024 |
SIRT1 Prevents R-Loops during Chronological Aging by Modulating DNA Replication at rDNA Loci BL Thakur, NA Kusi, S Mosavarpour, R Zhu, CE Redon, H Fu, A Dhall, ... Cells 12 (22), 2630, 2023 | 2 | 2023 |
A dual role of Cohesin in DNA DSB repair M Fedkenheuer, Y Shang, S Jung, K Fedkenheuer, S Park, D Mazza, ... Nature Communications 16 (1), 843, 2025 | 1 | 2025 |
Mechanism for local attenuation of DNA replication at double-strand breaks R Sebastian, EG Sun, M Fedkenheuer, H Fu, SK Jung, BL Thakur, ... Nature, 1-9, 2025 | | 2025 |