Stebėti
Sebastian Igelmann
Sebastian Igelmann
VIB-KU Leuven center for cancer biology
Patvirtintas el. paštas kuleuven.be
Pavadinimas
Cituota
Cituota
Metai
Metformin inhibits the senescence‐associated secretory phenotype by interfering with IKK/NF‐κ B activation
O Moiseeva, X Deschênes‐Simard, E St‐Germain, S Igelmann, G Huot, ...
Aging cell 12 (3), 489-498, 2013
6222013
Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation
X Deschênes-Simard, MF Gaumont-Leclerc, V Bourdeau, F Lessard, ...
Genes & development 27 (8), 900-915, 2013
2192013
Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway
F Lessard, S Igelmann, C Trahan, G Huot, E Saint-Germain, L Mignacca, ...
Nature Cell Biology 20 (7), 789, 2018
1412018
STAT3 and STAT5 activation in solid cancers
S Igelmann, HA Neubauer, G Ferbeyre
Cancers 11 (10), 1428, 2019
962019
Senescence gives insights into the morphogenetic evolution of anamniotes
É Villiard, JF Denis, FS Hashemi, S Igelmann, G Ferbeyre, S Roy
Biology open 6 (6), 891-896, 2017
552017
A hydride transfer complex reprograms NAD metabolism and bypasses senescence
S Igelmann, F Lessard, O Uchenunu, J Bouchard, A Fernandez-Ruiz, ...
Molecular Cell 81 (18), 3848-3865. e19, 2021
452021
Circumventing senescence is associated with stem cell properties and metformin sensitivity
X Deschênes‐Simard, M Parisotto, MC Rowell, B Le Calvé, S Igelmann, ...
Aging cell 18 (2), e12889, 2019
412019
Spatial metabolomics principles and application to cancer research
M Planque, S Igelmann, AMF Campos, SM Fendt
Current Opinion in Chemical Biology 76, 102362, 2023
372023
Ribosomal protein RPL22/eL22 regulates the cell cycle by acting as an inhibitor of the CDK4-cyclin D complex
N Del Toro, A Fernandez-Ruiz, L Mignacca, P Kalegari, MC Rowell, ...
Cell Cycle 18 (6-7), 759-770, 2019
292019
Liquid–liquid phase separation in cancer signaling, metabolism and anticancer therapy
S Igelmann, F Lessard, G Ferbeyre
Cancers 14 (7), 1830, 2022
142022
The NAMPT inhibitor FK866 increases metformin sensitivity in pancreatic cancer cells
M Parisotto, N Vuong-Robillard, P Kalegari, T Meharwade, L Joumier, ...
Cancers 14 (22), 5597, 2022
122022
Targeting ribosome biogenesis reinforces ERK-dependent senescence in pancreatic cancer
MC Rowell, X Deschênes-Simard, S Lopes-Paciencia, B Le Calve, ...
Cell Cycle 22 (19), 2172-2193, 2023
92023
Zinc controls PML nuclear body formation through regulation of a paralog specific auto-inhibition in SUMO1
M Lussier-Price, HM Wahba, XH Mascle, L Cappadocia, V Bourdeau, ...
Nucleic Acids Research 50 (14), 8331-8348, 2022
72022
HIF1α-dependent uncoupling of glycolysis suppresses tumor cell proliferation
AA Urrutia, C Mesa-Ciller, A Guajardo-Grence, HF Alkan, I Soro-Arnáiz, ...
Cell Reports 43 (4), 2024
62024
Cellular senescence limits translational readthrough
N Del Toro, F Lessard, J Bouchard, N Mobasheri, J Guillon, S Igelmann, ...
Biology open 10 (12), bio058688, 2021
62021
Senescent macrophages release inflammatory cytokines and RNA-loaded extracellular vesicles to circumvent fibroblast senescence
C Laliberté, B Bossé, V Bourdeau, LI Prieto, G Perron-Deshaies, ...
Biomedicines 12 (5), 1089, 2024
42024
Aspartate signalling drives lung metastasis via alternative translation
G Doglioni, J Fernández-García, S Igelmann, P Altea-Manzano, ...
Nature, 1-7, 2025
12025
Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics
D Papadopoli, R Palia, P Jovanovic, S Tabariès, E Ciccolini, V Sabourin, ...
bioRxiv, 2024.10. 25.620155, 2024
2024
Structural and functional characterization of the role of acetylation on the interactions of the human Atg8-family proteins with the autophagy receptor TP53INP2/DOR
MG Ali, HM Wahba, S Igelmann, N Cyr, G Ferbeyre, JG Omichinski
Autophagy 20 (9), 1948-1967, 2024
2024
Aspartate signaling increases the aggressiveness of lung metastases by inducing eIF5A mediated translation
G Doglioni, P Altea-Manzano, S Igelmann, J Fernandez-Garcia, ...
Mechanisms and Models of Cancer, Location: San Diego, California, 2023
2023
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Straipsniai 1–20