PT3: A Novel benzamide class histone deacetylase 3 inhibitor improves learning and memory in novel object recognition mouse model S Pulya, A Mahale, Y Bobde, G Routholla, T Patel, Swati, S Biswas, ... ACS Chemical Neuroscience 12 (5), 883-892, 2021 | 20 | 2021 |
Dapsone prolong delayed excitotoxic neuronal cell death by interacting with proapoptotic/survival signaling proteins A Mahale, R Kumar, LP Sarode, S Gakare, A Prakash, RR Ugale Journal of Stroke and Cerebrovascular Diseases 29 (8), 104848, 2020 | 18 | 2020 |
Pharmacological blockade of HDAC3 accelerates diabetic wound healing by regulating macrophage activation K Karnam, K Sedmaki, P Sharma, A Mahale, B Ghosh, OP Kulkarni Life Sciences 321, 121574, 2023 | 15 | 2023 |
Inhibition of autotaxin ameliorates LPA-mediated neuroinflammation and alleviates neurological dysfunction in acute hepatic encephalopathy S Roy, M Chakrabarti, H Dasgupta, A Mahale, S Tripathi, V Sharma, ... ACS Chemical Neuroscience 13 (19), 2829-2841, 2022 | 15 | 2022 |
Benzimidazole based bis-carboxamide derivatives as promising cytotoxic agents: Design, synthesis, in silico and tubulin polymerization inhibition K Laxmikeshav, P Sharma, M Palepu, P Sharma, A Mahale, J George, ... Journal of Molecular Structure 1271, 134078, 2023 | 12 | 2023 |
HDAC6 inhibition attenuates renal injury by reducing IL-1β secretion and RIP kinase mediated necroptosis in acute oxalate nephropathy K Sedmaki, K Karnam, P Sharma, A Mahale, G Routholla, B Ghosh, ... International Immunopharmacology 110, 108919, 2022 | 8 | 2022 |
Cyclo (Val-Pro) and Cyclo (Leu-Hydroxy-Pro) from Pseudomonas sp.(ABS-36) alleviates acute and chronic renal injury under in vitro and in vivo models (Ischemic reperfusion and … K Hira, P Sharma, A Mahale, OP Kulkarni, AS Begum International Immunopharmacology 103, 108494, 2022 | 7 | 2022 |
Benzimidazole derivatives as tubulin polymerization inhibitors: design, synthesis and in vitro cytotoxicity studies K Laxmikeshav, Z Rahman, A Mahale, DG Valapil, P Sharma, J George, ... Bioorganic & Medicinal Chemistry Letters 96, 129494, 2023 | 5 | 2023 |
Triazolo‐linked benzimidazoles as tubulin polymerization inhibitors and DNA intercalators: Design, synthesis, cytotoxicity, and docking studies K Laxmikeshav, M Sayali, G Devabattula, DG Valapil, A Mahale, ... Archiv der Pharmazie 356 (5), 2200449, 2023 | 5 | 2023 |
Swati,; Biswas, S.; Sharma, V.; Kulkarni, OP; Ghosh, B. PT3: A Novel Benzamide Class Histone Deacetylase 3 Inhibitor Improves Learning and Memory in Novel Object Recognition … S Pulya, A Mahale, Y Bobde, G Routholla, T Patel ACS Chem. Neurosci 12, 883-892, 2021 | 5 | 2021 |
Nickel-assisted selective detection of histidine and histidine-rich proteins via an ON-OFF-ON fluorescent probe and its imaging in live cells A Bandyopadhyay, AK Shukla, P Singh, A Mahale, SS Irukuvajjula, ... Journal of Photochemistry and Photobiology A: Chemistry 443, 114885, 2023 | 4 | 2023 |
Regioselective synthesis and in vitro cytotoxicity evaluation of 3-thiooxindole derivatives: Tubulin polymerization inhibition and apoptosis inducing studies AP Sakla, B Panda, A Mahale, P Sharma, K Laxmikeshav, MA Khan, ... Bioorganic & Medicinal Chemistry 90, 117297, 2023 | 4 | 2023 |
HDAC5 RNA interference ameliorates acute renal injury by upregulating KLF2 and inhibiting NALP3 expression in a mouse model of oxalate nephropathy P Sharma, K Karnam, A Mahale, K Sedmaki, VK Venuganti, OP Kulkarni International Immunopharmacology 112, 109264, 2022 | 4 | 2022 |
N-2-Hydroxypropylmethacrylamide–Polycaprolactone Polymeric Micelles in Co-delivery of Proteasome Inhibitor and Polyphenol: Exploration of Synergism or … S Rani, RK Sahoo, V Kumar, A Chaurasiya, O Kulkarni, A Mahale, ... Molecular Pharmaceutics 20 (1), 524-544, 2022 | 4 | 2022 |
Development of Benzimidazole‐Substituted Spirocyclopropyl Oxindole Derivatives as Cytotoxic Agents: Tubulin Polymerization Inhibition and Apoptosis Inducing Studies AP Sakla, MR Bazaz, A Mahale, P Sharma, DG Valapil, OP Kulkarni, ... ChemMedChem 19 (12), e202400052, 2024 | 2 | 2024 |
Development and Validation of a Fluorogenic Probe for Lysosomal Zinc Release AK Shukla, A Mahale, S Choudhary, P Sharma, OP Kulkarni, ... ChemBioChem 25 (4), e202300783, 2024 | 2 | 2024 |
A modular approach to fluorescent probes: Extending the scope of β-carboline scaffold to selective fluoride sensing and its application in the visualisation of fluoride-induced ROS AK Shukla, A Mahale, OP Kulkarni, A Bhattacharya Journal of Photochemistry and Photobiology A: Chemistry 437, 114453, 2023 | 2 | 2023 |
Pharmacological blockade of HDAC6 attenuates cancer progression by inhibiting IL-1β and modulating immunosuppressive response in OSCC A Mahale, G Routholla, S Lavanya, P Sharma, B Ghosh, OP Kulkarni International Immunopharmacology 132, 111921, 2024 | 1 | 2024 |
Sialic Acid Engineered Prodrug Nanoparticles for Codelivery of Bortezomib and Selenium in Tumor Bearing Mice S Rani, RK Sahoo, A Mahale, K Panchal, A Chaurasiya, O Kulkarni, ... Bioconjugate Chemistry 34 (9), 1528-1552, 2023 | 1 | 2023 |
Targeted intracellular delivery of antitubercular bioactive (s) to Mtb infected macrophages via transferrin functionalized nanoliposomes P Shrivastava, A Mahale, OP Kulkarni, SK Kashaw, SP Vyas International Journal of Pharmaceutics 642, 123189, 2023 | | 2023 |