Thrombocytopathy and endotheliopathy: crucial contributors to COVID-19 thromboinflammation SX Gu, T Tyagi, K Jain, VW Gu, SH Lee, JM Hwa, JM Kwan, DS Krause, ... Nature Reviews Cardiology 18 (3), 194-209, 2021 | 439 | 2021 |
Role of platelet mitochondria: life in a nucleus-free zone H Melchinger, K Jain, T Tyagi, J Hwa Frontiers in cardiovascular medicine 6, 153, 2019 | 199 | 2019 |
A guide to molecular and functional investigations of platelets to bridge basic and clinical sciences T Tyagi, K Jain, SX Gu, M Qiu, VW Gu, H Melchinger, H Rinder, KA Martin, ... Nature cardiovascular research 1 (3), 223-237, 2022 | 63 | 2022 |
Mitochondrial MsrB2 serves as a switch and transducer for mitophagy SH Lee, S Lee, J Du, K Jain, M Ding, AJ Kadado, G Atteya, Z Jaji, T Tyagi, ... EMBO molecular medicine 11 (8), e10409, 2019 | 58 | 2019 |
Upregulation of cytoprotective defense mechanisms and hypoxia-responsive proteins imparts tolerance to acute hypobaric hypoxia K Jain, G Suryakumar, R Prasad, L Ganju High Altitude Medicine & Biology 14 (1), 65-77, 2013 | 51 | 2013 |
Differential hypoxic tolerance is mediated by activation of heat shock response and nitric oxide pathway K Jain, G Suryakumar, L Ganju, SB Singh Cell Stress and Chaperones 19 (6), 801-812, 2014 | 48 | 2014 |
Age associated non-linear regulation of redox homeostasis in the anucleate platelet: Implications for CVD risk patients K Jain, T Tyagi, K Patell, Y Xie, AJ Kadado, SH Lee, T Yarovinsky, J Du, ... EBioMedicine 44, 28-40, 2019 | 43 | 2019 |
Differential activation of myocardial ER stress response: a possible role in hypoxic tolerance K Jain, G Suryakumar, R Prasad, L Ganju International journal of cardiology 168 (5), 4667-4677, 2013 | 35 | 2013 |
Platelet-derived TLT-1 promotes tumor progression by suppressing CD8+ T cells T Tyagi, K Jain, TO Yarovinsky, M Chiorazzi, J Du, C Castro, J Griffin, ... Journal of Experimental Medicine 220 (1), e20212218, 2022 | 25 | 2022 |
Amelioration of ER stress by 4-phenylbutyric acid reduces chronic hypoxia induced cardiac damage and improves hypoxic tolerance through upregulation of HIF-1α K Jain, G Suryakumar, L Ganju, SB Singh Vascular Pharmacology 83, 36-46, 2016 | 21 | 2016 |
Myocardial ER chaperone activation and protein degradation occurs due to synergistic, not individual, cold and hypoxic stress K Jain, G Suryakumar, R Prasad, SN Singh, L Ganju Biochimie 95 (10), 1897-1908, 2013 | 21 | 2013 |
Unfolded protein response differentially modulates the platelet phenotype K Jain, T Tyagi, J Du, X Hu, K Patell, KA Martin, J Hwa Circulation research 131 (4), 290-307, 2022 | 20 | 2022 |
Low-dose Aspirin prevents hypertension and cardiac fibrosis when thromboxane A2 is unrestrained I D'Agostino, S Tacconelli, A Bruno, A Contursi, L Mucci, X Hu, Y Xie, ... Pharmacological Research 170, 105744, 2021 | 19 | 2021 |
Enhanced hypoxic tolerance by Seabuckthorn is due to upregulation of HIF-1α and attenuation of ER stress K Jain, G Suryakumar, R Prasad, L Ganju, SB Singh journal of applied biomedicine 14 (1), 71-83, 2016 | 10 | 2016 |
Author's response to “platelet antioxidants: A conundrum in aging” K Jain, T Tyagi, CN Ionescu, J Hwa EBioMedicine 47, 31-32, 2019 | 2 | 2019 |
Lipid remodeling in megakaryocyte differentiation and platelet biogenesis K Jain, T Tyagi, J Hwa Nature cardiovascular research 2 (9), 803-804, 2023 | 1 | 2023 |
“CO” ping with a sticky situation K Jain, T Tyagi, J Hwa Arteriosclerosis, thrombosis, and vascular biology 40 (10), 2344-2345, 2020 | 1 | 2020 |
Sea buckthorn (H. rhamnoides L.) mediated acute hypoxic tolerance in the skeletal muscle of rats by differential activation of energy metabolism and enhanced antioxidants GK Keshri, A Gupta, K Jain, G Suryakumar, P Sharma, S Gola, A Yadav, ... International Journal of Pharmaceutical Sciences and Research 6 (12), 5259, 2015 | 1 | 2015 |
Demographic diversity in platelet function and response to antiplatelet therapy K Jain, T Tyagi, SX Gu, EVS Faustino, J Hwa Trends in Pharmacological Sciences, 2024 | | 2024 |
Treatment of Human Engineered Heart Tissue with Serum from Cancer Patients with Clonal Hematopoiesis of Indeterminate Potential Cytokine Leads to Impaired Function H Kaur, S Halder, J Espinoza, N Chen, J VanOudenhove, G Biancon, ... Circulation 150 (Suppl_1), A4144255-A4144255, 2024 | | 2024 |