| Mitochondrial proteostasis in the context of cellular and organismal health and aging EA Moehle, K Shen, A Dillin Journal of Biological Chemistry 294 (14), 5396-5407, 2019 | 170 | 2019 |
| Mitochondria as cellular and organismal signaling hubs K Shen, CL Pender, R Bar-Ziv, H Zhang, K Wickham, E Willey, J Durieux, ... Annual review of cell and developmental biology 38 (1), 179-218, 2022 | 123 | 2022 |
| Structure and mechanism of the UvrA–UvrB DNA damage sensor D Pakotiprapha, M Samuels, K Shen, JH Hu, D Jeruzalmi Nature structural & molecular biology 19 (3), 291-298, 2012 | 90 | 2012 |
| Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract K Shen, B Calamini, JA Fauerbach, B Ma, SH Shahmoradian, ... Elife 5, e18065, 2016 | 76 | 2016 |
| Super-resolution fluorescence of huntingtin reveals growth of globular species into short fibers and coexistence of distinct aggregates WC Duim, Y Jiang, K Shen, J Frydman, WE Moerner ACS chemical biology 9 (12), 2767-2778, 2014 | 76 | 2014 |
| Structure and dynamics of the huntingtin exon-1 N-terminus: a solution NMR perspective M Baias, PES Smith, K Shen, LA Joachimiak, S Zerko, W Kozminski, ... Journal of the American Chemical Society 139 (3), 1168-1176, 2017 | 68 | 2017 |
| Systemic regulation of mitochondria by germline proteostasis prevents protein aggregation in the soma of C. elegans G Calculli, HJ Lee, K Shen, U Pham, M Herholz, A Trifunovic, A Dillin, ... Science advances 7 (26), eabg3012, 2021 | 48 | 2021 |
| Dual role of ribosome-binding domain of NAC as a potent suppressor of protein aggregation and aging-related proteinopathies K Shen, M Gamerdinger, R Chan, K Gense, EM Martin, N Sachs, ... Molecular cell 74 (4), 729-741. e7, 2019 | 48 | 2019 |
| Cryo-electron tomography provides topological insights into mutant huntingtin exon 1 and polyQ aggregates JG Galaz-Montoya, SH Shahmoradian, K Shen, J Frydman, W Chiu Communications Biology 4 (1), 849, 2021 | 26 | 2021 |
| Lysosomal recycling of amino acids affects ER quality control R Higuchi-Sanabria, K Shen, N Kelet, PA Frankino, J Durieux, R Bar-Ziv, ... Science Advances 6 (26), eaaz9805, 2020 | 22 | 2020 |
| Huntingtin’s N-terminus rearrangements in the presence of membranes: A joint spectroscopic and computational perspective GR Levy, K Shen, Y Gavrilov, PES Smith, Y Levy, R Chan, J Frydman, ... ACS Chemical Neuroscience 10 (1), 472-481, 2018 | 21 | 2018 |
| Disease-related Huntingtin seeding activities in cerebrospinal fluids of Huntington’s disease patients CYD Lee, N Wang, K Shen, M Stricos, P Langfelder, KH Cheon, ... Scientific Reports 10 (1), 20295, 2020 | 17 | 2020 |
| The germline coordinates mitokine signaling K Shen, J Durieux, CG Mena, BM Webster, CK Tsui, H Zhang, L Joe, ... Cell 187 (17), 4605-4620. e17, 2024 | 11 | 2024 |
| Cross-species screening platforms identify EPS-8 as a critical link for mitochondrial stress and actin stabilization EA Moehle, R Higuchi-Sanabria, CK Tsui, S Homentcovschi, KM Tharp, ... Science Advances 7 (44), eabj6818, 2021 | 9 | 2021 |
| The interplay between the chaperonin TRiC and N-terminal region of Huntingtin mediates Huntington’s Disease aggregation and pathogenesis K Shen, J Frydman Protein quality control in neurodegenerative diseases, 121-132, 2012 | 7 | 2012 |
| Olfaction regulates peripheral mitophagy and mitochondrial function JG Dishart, CL Pender, K Shen, H Zhang, M Ly, MB Webb, A Dillin Science Advances 10 (25), eadn0014, 2024 | 5 | 2024 |
| Topological Insights into Mutant Huntingtin Exon 1 and PolyQ Aggregates by Cryo-Electron Tomography JG Galaz-Montoya, SH Shahmoradian, K Shen, J Frydman, W Chiu bioRxiv, 2020.12. 08.417048, 2020 | 1 | 2020 |
| Germline mitochondria integrate neuronal cell nonautonomous signaling for the mitochondrial unfolded protein response K Shen, J Durieux, CG Mena, BM Webster, K Berendzen, A Dillin bioRxiv, 2023.08. 21.554217, 2023 | | 2023 |
| Linking the Conformational Landscape of Huntingtin to Proteostasis and Neurotoxicity in Huntington's Disease K Shen Stanford University, 2016 | | 2016 |