| Centrosome amplification is sufficient to promote spontaneous tumorigenesis in mammals MS Levine, B Bakker, B Boeckx, J Moyett, J Lu, B Vitre, DC Spierings, ... Developmental cell 40 (3), 313-322. e5, 2017 | 398 | 2017 |
| Single-cell sequencing reveals karyotype heterogeneity in murine and human malignancies B Bakker, A Taudt, ME Belderbos, D Porubsky, DCJ Spierings, ... Genome biology 17, 1-15, 2016 | 262 | 2016 |
| Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids ACF Bolhaqueiro, B Ponsioen, B Bakker, SJ Klaasen, E Kucukkose, ... Nature genetics 51 (5), 824-834, 2019 | 225 | 2019 |
| cGAS–STING drives the IL-6-dependent survival of chromosomally instable cancers C Hong, M Schubert, AE Tijhuis, M Requesens, M Roorda, ... Nature 607 (7918), 366-373, 2022 | 221 | 2022 |
| Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition Y Cohen-Sharir, JM McFarland, M Abdusamad, C Marquis, SV Bernhard, ... Nature 590 (7846), 486-491, 2021 | 220 | 2021 |
| Analysis of Mitosis and Antimitotic Drug Responses in Tumors by In Vivo Microscopy and Single-Cell Pharmacodynamics JD Orth, RH Kohler, F Foijer, PK Sorger, R Weissleder, TJ Mitchison Cancer research 71 (13), 4608-4616, 2011 | 176 | 2011 |
| p53 prohibits propagation of chromosome segregation errors that produce structural aneuploidies M Soto, JA Raaijmakers, B Bakker, DCJ Spierings, PM Lansdorp, F Foijer, ... Cell reports 19 (12), 2423-2431, 2017 | 170 | 2017 |
| Single-cell whole genome sequencing reveals no evidence for common aneuploidy in normal and Alzheimer’s disease neurons H van den Bos, DCJ Spierings, A Taudt, B Bakker, D Porubský, ... Genome biology 17, 1-9, 2016 | 166 | 2016 |
| Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy MR Ippolito, V Martis, S Martin, AE Tijhuis, C Hong, R Wardenaar, ... Developmental cell 56 (17), 2440-2454. e6, 2021 | 153 | 2021 |
| Loss of Rb proteins causes genomic instability in the absence of mitogenic signaling T van Harn, F Foijer, M van Vugt, R Banerjee, F Yang, A Oostra, H Joenje, ... Genes & development 24 (13), 1377-1388, 2010 | 151 | 2010 |
| FoxM1 repression during human aging leads to mitotic decline and aneuploidy-driven full senescence JC Macedo, S Vaz, B Bakker, R Ribeiro, PL Bakker, JM Escandell, ... Nature communications 9 (1), 2834, 2018 | 135 | 2018 |
| Non-random mis-segregation of human chromosomes JT Worrall, N Tamura, A Mazzagatti, N Shaikh, T van Lingen, B Bakker, ... Cell reports 23 (11), 3366-3380, 2018 | 133 | 2018 |
| Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress F Foijer, SZ Xie, JE Simon, PL Bakker, N Conte, SH Davis, E Kregel, ... Proceedings of the National Academy of Sciences 111 (37), 13427-13432, 2014 | 124 | 2014 |
| Progression through mitosis promotes PARP inhibitor-induced cytotoxicity in homologous recombination-deficient cancer cells PM Schoonen, F Talens, C Stok, E Gogola, AM Heijink, P Bouwman, ... Nature communications 8 (1), 15981, 2017 | 118 | 2017 |
| Genetic instability from a single S phase after whole-genome duplication S Gemble, R Wardenaar, K Keuper, N Srivastava, M Nano, AS Macé, ... Nature 604 (7904), 146-151, 2022 | 117 | 2022 |
| DNA replication vulnerabilities render ovarian cancer cells sensitive to poly (ADP-ribose) glycohydrolase inhibitors N Pillay, A Tighe, L Nelson, S Littler, C Coulson-Gilmer, N Bah, A Golder, ... Cancer Cell 35 (3), 519-533. e8, 2019 | 112 | 2019 |
| Nuclear chromosome locations dictate segregation error frequencies SJ Klaasen, MA Truong, RH van Jaarsveld, I Koprivec, V Štimac, ... Nature 607 (7919), 604-609, 2022 | 99 | 2022 |
| Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition‐mediated genomic instability, inflammatory signaling, and cytotoxicity in BRCA2‐deficient … PM Schoonen, YP Kok, E Wierenga, B Bakker, F Foijer, DCJ Spierings, ... Molecular oncology 13 (11), 2422-2440, 2019 | 87 | 2019 |
| Deletion of the MAD2L1 spindle assembly checkpoint gene is tolerated in mouse models of acute T-cell lymphoma and hepatocellular carcinoma F Foijer, LA Albacker, B Bakker, DC Spierings, Y Yue, SZ Xie, S Davis, ... Elife 6, e20873, 2017 | 80 | 2017 |
| How to count chromosomes in a cell: An overview of current and novel technologies B Bakker, H van den Bos, PM Lansdorp, F Foijer BioEssays 37 (5), 570-577, 2015 | 80 | 2015 |
