Stebėti
Bennett Childs
Bennett Childs
Patvirtintas el. paštas mayo.edu
Pavadinimas
Cituota
Cituota
Metai
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
DJ Baker, T Wijshake, T Tchkonia, NK LeBrasseur, BG Childs, ...
Nature 479 (7372), 232-236, 2011
39792011
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
DJ Baker, BG Childs, M Durik, ME Wijers, CJ Sieben, J Zhong, ...
Nature 530 (7589), 184-189, 2016
27522016
Cellular senescence in aging and age-related disease: from mechanisms to therapy
BG Childs, M Durik, DJ Baker, JM Van Deursen
Nature medicine 21 (12), 1424-1435, 2015
22352015
Senescent intimal foam cells are deleterious at all stages of atherosclerosis
BG Childs, DJ Baker, T Wijshake, CA Conover, J Campisi, ...
Science 354 (6311), 472-477, 2016
11822016
Senescent cells: an emerging target for diseases of ageing
BG Childs, M Gluscevic, DJ Baker, RM Laberge, D Marquess, ...
Nature reviews Drug discovery 16 (10), 718-735, 2017
11572017
Senescence and apoptosis: dueling or complementary cell fates?
BG Childs, DJ Baker, JL Kirkland, J Campisi, JM Van Deursen
EMBO reports 15 (11), 1139-1153, 2014
10032014
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels
CCS Chini, TR Peclat, GM Warner, S Kashyap, JM Espindola-Netto, ...
Nature metabolism 2 (11), 1284-1304, 2020
2592020
Senescent cells: a therapeutic target for cardiovascular disease
BG Childs, H Li, JM Van Deursen
The Journal of clinical investigation 128 (4), 1217-1228, 2018
2002018
Spartan deficiency causes genomic instability and progeroid phenotypes
RS Maskey, MS Kim, DJ Baker, B Childs, LA Malureanu, KB Jeganathan, ...
Nature communications 5 (1), 5744, 2014
1362014
Progressive cellular senescence mediates renal dysfunction in ischemic nephropathy
SR Kim, AS Puranik, K Jiang, X Chen, XY Zhu, I Taylor, ...
Journal of the American Society of Nephrology 32 (8), 1987-2004, 2021
752021
Treatment for osteoarthritis in a joint by administering a means for inhibiting MDM2
RM Laberge, J Campisi, A Davalos, M Demaria, N David, AP Vasserot, ...
US Patent 9,993,472, 2018
63*2018
A. Saltness R, Jeganathan KB, Verzosa GC, Pezeshki A, Khazaie K, Miller JD, van Deursen JM (2016) Naturally occurring p16 Ink4a-positive cells shorten healthy lifespan
DJ Baker, BG Childs, M Durik, ME Wijers, CJ Sieben, J Zhong
Nature 530 (7589), 184-189, 0
55
Senescent cells suppress innate smooth muscle cell repair functions in atherosclerosis
BG Childs, C Zhang, F Shuja, I Sturmlechner, S Trewartha, RF Velasco, ...
Nature aging 1 (8), 698-714, 2021
492021
Glomerular endothelial cell senescence drives age‐related kidney disease through PAI‐1
C Cohen, O Le Goff, F Soysouvanh, F Vasseur, M Tanou, C Nguyen, ...
EMBO Molecular Medicine 13 (11), e14146, 2021
462021
Unit dose of a cis-imidazoline for treating an osteoarthritic joint by removing senescent cells
RM Laberge, J Campisi, A Davalos, M Demaria, N David, AP Vasserot, ...
US Patent 9,849,128, 2017
34*2017
Cellular identification and quantification of senescence-associated β-galactosidase activity in vivo
BG Childs, TJ Bussian, DJ Baker
Cellular Senescence: Methods and Protocols, 31-38, 2019
222019
Treatment of ophthalmic conditions by selectively removing senescent cells from the eye
RM Laberge, J Campisi, M Demaria, N David, AP Vasserot, JL Kirkland, ...
US Patent 10,010,546, 2018
202018
Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders
RM Laberge, J Campisi, A Davalos, M Demaria, N David, AP Vasserot, ...
US Patent App. 15/455,630, 2017
182017
Method of optimizing conditions for selectively removing a plurality of senescent cells from a tissue or a mixed cell population
RM Laberge, J Campisi, A Davalos, M Demaria, N David, Y Zhu, ...
US Patent 10,213,426, 2019
162019
Treatment for osteoarthritis by intra-articular administration of a cis-imidazoline
RM Laberge, J Campisi, A Davalos, M Demaria, N David, AP Vasserot, ...
US Patent 9,855,266, 2018
162018
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