| Effects of common mutations in the SARS-CoV-2 Spike RBD and its ligand, the human ACE2 receptor on binding affinity and kinetics MI Barton, SA MacGowan, MA Kutuzov, O Dushek, GJ Barton, ... Elife 10, e70658, 2021 | 342 | 2021 |
| Chlorophylls, symmetry, chirality, and photosynthesis MO Senge, AA Ryan, KA Letchford, SA MacGowan, T Mielke Symmetry 6 (3), 781-843, 2014 | 246 | 2014 |
| Conformational control of cofactors in nature–the influence of protein-induced macrocycle distortion on the biological function of tetrapyrroles MO Senge, SA MacGowan, JM O'Brien Chemical Communications 51 (96), 17031-17063, 2015 | 223 | 2015 |
| Severe dermatitis, multiple allergies, and metabolic wasting syndrome caused by a novel mutation in the N-terminal plakin domain of desmoplakin MA McAleer, E Pohler, FJD Smith, NJ Wilson, C Cole, S MacGowan, ... Journal of Allergy and Clinical Immunology 136 (5), 1268-1276, 2015 | 133 | 2015 |
| Mutations involving the SRY-related gene SOX8 are associated with a spectrum of human reproductive anomalies MF Portnoi, MC Dumargne, S Rojo, SF Witchel, AJ Duncan, C Eozenou, ... Human molecular genetics 27 (7), 1228-1240, 2018 | 88 | 2018 |
| PDBe-KB: a community-driven resource for structural and functional annotations M Varadi, J Berrisford, M Deshpande, SS Nair, A Gutmanas, D Armstrong, ... Nucleic Acids Research 48 (D1), D344-D353, 2020 | 86 | 2020 |
| Expanding the clinical spectrum of hereditary fibrosing poikiloderma with tendon contractures, myopathy and pulmonary fibrosis due to FAM111B mutations S Mercier, S Küry, E Salort-Campana, A Magot, U Agbim, T Besnard, ... Orphanet journal of rare diseases 10, 1-16, 2015 | 54 | 2015 |
| Conformational control of cofactors in nature—functional tetrapyrrole conformations in the photosynthetic reaction centers of purple bacteria SA MacGowan, MO Senge Chemical Communications 47 (42), 11621-11623, 2011 | 22 | 2011 |
| The Dundee resource for sequence analysis and structure prediction SA MacGowan, F Madeira, T Britto‐Borges, M Warowny, A Drozdetskiy, ... Protein Science 29 (1), 277-297, 2020 | 21 | 2020 |
| Contribution of bacteriochlorophyll conformation to the distribution of site-energies in the FMO protein SA MacGowan, MO Senge Biochimica et Biophysica Acta (BBA)-Bioenergetics 1857 (4), 427-442, 2016 | 21 | 2016 |
| Computational Quantification of the Physicochemical Effects of Heme Distortion: Redox Control in the Reaction Center Cytochrome Subunit of Blastochloris viridis SA MacGowan, MO Senge Inorganic Chemistry 52 (3), 1228-1237, 2013 | 21 | 2013 |
| Missense variants in ACE2 are predicted to encourage and inhibit interaction with SARS-CoV-2 Spike and contribute to genetic risk in COVID-19 SA MacGowan, GJ Barton BioRxiv, 2020.05. 03.074781, 2020 | 19 | 2020 |
| The structural chemistry of isolated chlorophylls MO Senge, SA MacGowan Handbook of porphyrin science 13, 253-297, 2010 | 15 | 2010 |
| Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19: A case study in affinity … SA MacGowan, MI Barton, M Kutuzov, O Dushek, PA van der Merwe, ... PLoS Computational Biology 18 (3), e1009922, 2022 | 12 | 2022 |
| Disease related single point mutations alter the global dynamics of a tetratricopeptide (TPR) α-solenoid domain S Llabrés, MI Tsenkov, SA MacGowan, GJ Barton, U Zachariae Journal of structural biology 209 (1), 107405, 2020 | 12 | 2020 |
| Ankyrin repeats in context with human population variation JS Utgés, MI Tsenkov, NJM Dietrich, SA MacGowan, GJ Barton PLoS Computational Biology 17 (8), e1009335, 2021 | 11 | 2021 |
| Chlorophylls, symmetry, chirality, and photosynthesis. Symmetry 6: 781–843 MO Senge, AA Ryan, KA Letchford, SA MacGowan, T Mielke | 11 | 2014 |
| Human missense variation is constrained by domain structure and highlights functional and pathogenic residues SA MacGowan, F Madeira, T Britto-Borges, MS Schmittner, C Cole, ... BioRxiv, 127050, 2017 | 10 | 2017 |
| Symmetry 2014; 6: 781–843 MO Senge, AA Ryan, KA Letchford, SA MacGowan, T Mielke Crossref, Web of Science, 0 | 4 | |
| Classification of likely functional class for ligand binding sites identified from fragment screening JS Utgés, SA MacGowan, CM Ives, GJ Barton Communications Biology 7 (1), 320, 2024 | 3 | 2024 |
Geoffrey J BartonProfessor of Bioinformatics, University of DundeePatvirtintas el. paštas dundee.ac.uk