| Activation mechanism of the calcium-activated chloride channel TMEM16A revealed by cryo-EM C Paulino, V Kalienkova, AKM Lam, Y Neldner, R Dutzler Nature 552 (7685), 421-425, 2017 | 291 | 2017 |
| Structure of a volume-regulated anion channel of the LRRC8 family D Deneka, M Sawicka, AKM Lam, C Paulino, R Dutzler Nature 558 (7709), 254-259, 2018 | 194 | 2018 |
| Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A C Paulino, Y Neldner, AKM Lam, V Kalienkova, JD Brunner, S Schenck, ... elife 6, e26232, 2017 | 159 | 2017 |
| Cryo-EM structure of the human neutral amino acid transporter ASCT2 AA Garaeva, GT Oostergetel, C Gati, A Guskov, C Paulino, DJ Slotboom Nature structural & molecular biology 25 (6), 515-521, 2018 | 156 | 2018 |
| Cryo-EM structures and functional characterization of the murine lipid scramblase TMEM16F C Alvadia, NK Lim, V Clerico Mosina, GT Oostergetel, R Dutzler, ... Elife 8, e44365, 2019 | 149 | 2019 |
| A one-gate elevator mechanism for the human neutral amino acid transporter ASCT2 AA Garaeva, A Guskov, DJ Slotboom, C Paulino Nature communications 10 (1), 3427, 2019 | 110 | 2019 |
| Stepwise activation mechanism of the scramblase nhTMEM16 revealed by cryo-EM V Kalienkova, V Clerico Mosina, L Bryner, GT Oostergetel, R Dutzler, ... Elife 8, e44364, 2019 | 107 | 2019 |
| Structure and transport mechanism of the sodium/proton antiporter MjNhaP1 C Paulino, D Wöhlert, E Kapotova, Ö Yildiz, W Kühlbrandt Elife 3, e03583, 2014 | 94 | 2014 |
| The groovy TMEM16 family: molecular mechanisms of lipid scrambling and ion conduction V Kalienkova, VC Mosina, C Paulino Journal of Molecular Biology 433 (16), 166941, 2021 | 87 | 2021 |
| Structure of the archaeal Na+/H+ antiporter NhaP1 and functional role of transmembrane helix 1 P Goswami, C Paulino, D Hizlan, J Vonck, Ö Yildiz, W Kühlbrandt The EMBO journal 30 (2), 439-449, 2011 | 77 | 2011 |
| Rational design of ASCT2 inhibitors using an integrated experimental-computational approach RAA Garibsingh, E Ndaru, AA Garaeva, Y Shi, L Zielewicz, P Zakrepine, ... Proceedings of the National Academy of Sciences 118 (37), e2104093118, 2021 | 58 | 2021 |
| Gating the pore of the calcium-activated chloride channel TMEM16A AKM Lam, J Rheinberger, C Paulino, R Dutzler Nature communications 12 (1), 785, 2021 | 52 | 2021 |
| Keeping it simple, transport mechanism and pH regulation in Na+/H+ exchangers O Călinescu, C Paulino, W Kühlbrandt, K Fendler Journal of biological chemistry 289 (19), 13168-13176, 2014 | 51 | 2014 |
| Gating by ionic strength and safety check by cyclic-di-AMP in the ABC transporter OpuA HR Sikkema, M van den Noort, J Rheinberger, M de Boer, ST Krepel, ... Science Advances 6 (47), eabd7697, 2020 | 50 | 2020 |
| Cryo-EM structures of KdpFABC suggest a K+ transport mechanism via two inter-subunit half-channels C Stock, L Hielkema, I Tascón, D Wunnicke, GT Oostergetel, M Azkargorta, ... Nature communications 9 (1), 4971, 2018 | 46 | 2018 |
| pH-and sodium-induced changes in a sodium/proton antiporter C Paulino, W Kühlbrandt Elife 3, e01412, 2014 | 39 | 2014 |
| Biparatopic sybodies neutralize SARS‐CoV‐2 variants of concern and mitigate drug resistance JD Walter, M Scherer, CAJ Hutter, AA Garaeva, I Zimmermann, M Wyss, ... EMBO reports 23 (4), e54199, 2022 | 36 | 2022 |
| Optimized cryo-EM data-acquisition workflow by sample-thickness determination J Rheinberger, G Oostergetel, GP Resch, C Paulino Biological Crystallography 77 (5), 565-571, 2021 | 35 | 2021 |
| Structural basis for the activation of the lipid scramblase TMEM16F M Arndt, C Alvadia, MS Straub, V Clerico Mosina, C Paulino, R Dutzler Nature communications 13 (1), 6692, 2022 | 28 | 2022 |
| Cryo-EM studies of membrane proteins at 200 keV C Thangaratnarajah, J Rheinberger, C Paulino Current Opinion in Structural Biology 76, 102440, 2022 | 17 | 2022 |