T cell factor 1: A master regulator of the T cell response in disease G Escobar, D Mangani, AC Anderson Science immunology 5 (53), eabb9726, 2020 | 154 | 2020 |
Endogenous glucocorticoid signaling regulates CD8+ T cell differentiation and development of dysfunction in the tumor microenvironment N Acharya, A Madi, H Zhang, M Klapholz, G Escobar, S Dulberg, ... immunity 53 (3), 658-671. e6, 2020 | 150 | 2020 |
MiR-221/222 target the DNA methyltransferase MGMT in glioma cells C Quintavalle, D Mangani, G Roscigno, G Romano, A Diaz-Lagares, ... PloS one 8 (9), e74466, 2013 | 121 | 2013 |
The network of immunosuppressive pathways in glioblastoma D Mangani, M Weller, P Roth Biochemical pharmacology 130, 1-9, 2017 | 111 | 2017 |
CLA-supplemented diet accelerates experimental colorectal cancer by inducing TGF-β-producing macrophages and T cells TG Moreira, LS Horta, AC Gomes-Santos, RP Oliveira, N Queiroz, ... Mucosal Immunology 12 (1), 188-199, 2019 | 38 | 2019 |
Tumor immunogenicity dictates reliance on TCF1 in CD8+ T cells for response to immunotherapy G Escobar, K Tooley, JP Oliveras, L Huang, H Cheng, ML Bookstaver, ... Cancer Cell 41 (9), 1662-1679. e7, 2023 | 32 | 2023 |
Limited role for transforming growth factor–β pathway activation-mediated escape from VEGF inhibition in murine glioma models D Mangani, M Weller, E Seyed Sadr, E Willscher, K Seystahl, ... Neuro-oncology 18 (12), 1610-1621, 2016 | 32 | 2016 |
Charting the cellular biogeography in colitis reveals fibroblast trajectories and coordinated spatial remodeling P Cadinu, KN Sivanathan, A Misra, RJ Xu, D Mangani, E Yang, JM Rone, ... Cell 187 (8), 2010-2028. e30, 2024 | 31 | 2024 |
PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis TG Moreira, D Mangani, LM Cox, J Leibowitz, ELC Lobo, MA Oliveira, ... Nature Communications 12 (1), 4907, 2021 | 30 | 2021 |
Learning from the nexus of autoimmunity and cancer D Mangani, D Yang, AC Anderson Immunity 56 (2), 256-271, 2023 | 18 | 2023 |
Emerging molecular networks in Burkitt's lymphoma D Mangani, A Roberti, F Rizzolio, A Giordano Journal of cellular biochemistry 114 (1), 35-38, 2013 | 15 | 2013 |
Nasal administration of anti-CD3 mAb (Foralumab) downregulates NKG7 and increases TGFB1 and GIMAP7 expression in T cells in subjects with COVID-19 T G. Moreira, CD Gauthier, L Murphy, TB Lanser, A Paul, KTF Matos, ... Proceedings of the National Academy of Sciences 120 (11), e2220272120, 2023 | 13 | 2023 |
T cell factor 1: A master regulator of the T cell response in disease. Sci. Immunol. 5, eabb9726 G Escobar, D Mangani, AC Anderson | 11 | 2020 |
Pan-cancer mapping of single CD8+ T cell profiles reveals a TCF1: CXCR6 axis regulating CD28 co-stimulation and anti-tumor immunity K Tooley, L Jerby, G Escobar, SH Krovi, D Mangani, G Dandekar, ... Cell Reports Medicine 5 (7), 2024 | 5 | 2024 |
Dietary protein modulates intestinal dendritic cells to establish mucosal homeostasis TG Moreira, LM Cox, P Da Silva, D Mangani, MG De Oliveira, G Escobar, ... Mucosal Immunology 17 (5), 911-922, 2024 | 3 | 2024 |
A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance RT Mertens, A Misra, P Xiao, S Baek, JM Rone, D Mangani, ... Immunity 57 (9), 2077-2094. e12, 2024 | 3 | 2024 |
Transcription factor TCF1 binds to RORγt and orchestrates a regulatory network that determines homeostatic Th17 cell state D Mangani, A Subramanian, L Huang, H Cheng, SH Krovi, Y Wu, D Yang, ... Immunity 57 (11), 2565-2582. e6, 2024 | 2 | 2024 |
An endogenous glucocorticoid-cytokine signaling circuit promotes CD8+ T cell dysfunction in the tumor microenvironment N Acharya, A Madi, H Zhang, M Klapholz, E Christian, KO Dixon, G Fell, ... bioRxiv, 799759, 2019 | 2 | 2019 |
964 Dynamic immune landscapes during melanoma progression reveal a role for endogenous opioids in driving T cell dysfunction D Mangani, L Huang, M Singer, R Li, R Barilla, G Escobar, K Tooley, ... Journal for ImmunoTherapy of Cancer 10 (Suppl 2), 2022 | 1 | 2022 |
A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance D Mangani, KN Sivanathan, AS Arojojoye, SG Awuah, I Lee, GP Shi, ... Immunity 57, 1-18, 2024 | | 2024 |