Driver mutations in histone H3. 3 and chromatin remodelling genes in paediatric glioblastoma J Schwartzentruber, A Korshunov, XY Liu, DTW Jones, E Pfaff, K Jacob, ... Nature 482 (7384), 226-231, 2012 | 2817 | 2012 |
DNA methylation-based classification of central nervous system tumours D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ... Nature 555 (7697), 469-474, 2018 | 2629 | 2018 |
Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma D Sturm, H Witt, V Hovestadt, DA Khuong-Quang, DTW Jones, ... Cancer cell 22 (4), 425-437, 2012 | 2062 | 2012 |
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics A Sottoriva, I Spiteri, SGM Piccirillo, A Touloumis, VP Collins, JC Marioni, ... Proceedings of the National Academy of Sciences 110 (10), 4009-4014, 2013 | 2027 | 2013 |
Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ... Cancer cell 27 (5), 728-743, 2015 | 1192 | 2015 |
Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas M Kool, A Korshunov, M Remke, DTW Jones, M Schlanstein, PA Northcott, ... Acta neuropathologica 123, 473-484, 2012 | 1186 | 2012 |
Tandem Duplication Producing a Novel Oncogenic BRAF Fusion Gene Defines the Majority of Pilocytic Astrocytomas DTW Jones, S Kocialkowski, L Liu, DM Pearson, LM Backlund, K Ichimura, ... Cancer research 68 (21), 8673-8677, 2008 | 1017 | 2008 |
Dissecting the genomic complexity underlying medulloblastoma DTW Jones, N Jäger, M Kool, T Zichner, B Hutter, M Sultan, YJ Cho, ... Nature 488 (7409), 100-105, 2012 | 980 | 2012 |
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer G Van Haaften, GL Dalgliesh, H Davies, L Chen, G Bignell, C Greenman, ... Nature genetics 41 (5), 521-523, 2009 | 937 | 2009 |
New brain tumor entities emerge from molecular classification of CNS-PNETs D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ... Cell 164 (5), 1060-1072, 2016 | 911 | 2016 |
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ... Nature genetics 45 (8), 927-932, 2013 | 854 | 2013 |
Genes for Epidermal Growth Factor Receptor, Transforming Growth Factor α, and Epidermal Growth Factor and Their Expression in Human Gliomas in Vivo AJ Ekstrand, CD James, WK Cavenee, B Seliger, RF Pettersson, ... Cancer research 51 (8), 2164-2172, 1991 | 853 | 1991 |
Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition M Kool, DTW Jones, N Jäger, PA Northcott, TJ Pugh, V Hovestadt, ... Cancer cell 25 (3), 393-405, 2014 | 844 | 2014 |
DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis F Sahm, D Schrimpf, D Stichel, DTW Jones, T Hielscher, S Schefzyk, ... The lancet oncology 18 (5), 682-694, 2017 | 819 | 2017 |
Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas S Bender, Y Tang, AM Lindroth, V Hovestadt, DTW Jones, M Kool, ... Cancer cell 24 (5), 660-672, 2013 | 817 | 2013 |
Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1p J Reifenberger, G Reifenberger, L Liu, CD James, W Wechsler, ... The American journal of pathology 145 (5), 1175, 1994 | 805 | 1994 |
Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N-and/or C-terminal tails. AJ Ekstrand, N Sugawa, CD James, VP Collins Proceedings of the National Academy of Sciences 89 (10), 4309-4313, 1992 | 789 | 1992 |
Identical splicing of aberrant epidermal growth factor receptor transcripts from amplified rearranged genes in human glioblastomas. N Sugawa, AJ Ekstrand, CD James, VP Collins Proceedings of the National Academy of Sciences 87 (21), 8602-8606, 1990 | 768 | 1990 |
IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas K Ichimura, DM Pearson, S Kocialkowski, LM Bäcklund, R Chan, ... Neuro-oncology 11 (4), 341-347, 2009 | 759 | 2009 |
Amplification and Overexpression of the MDM2 Gene in a Subset of Human Malignant Gliomas without p53 Mutations G Reifenberger, L Liu, K Ichimura, EE Schmidt, VP Collins Cancer research 53 (12), 2736-2739, 1993 | 758 | 1993 |