| The Concise Guide to PHARMACOLOGY 2021/22: G protein‐coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, A Mathie, ... British journal of pharmacology 178, S27-S156, 2021 | 1303 | 2021 |
| The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors SPH Alexander, A Christopoulos, AP Davenport, E Kelly, AA Mathie, ... British journal of pharmacology 180, S23-S144, 2023 | 186 | 2023 |
| The microglial NLRP3 inflammasome is activated by amyotrophic lateral sclerosis proteins V Deora, JD Lee, EA Albornoz, L McAlary, CJ Jagaraj, AAB Robertson, ... Glia 68 (2), 407-421, 2020 | 184 | 2020 |
| The complement receptor C5aR2: a powerful modulator of innate and adaptive immunity XX Li, JD Lee, C Kemper, TM Woodruff The Journal of Immunology 202 (12), 3339-3348, 2019 | 135 | 2019 |
| SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein EA Albornoz, AA Amarilla, N Modhiran, S Parker, XX Li, DK Wijesundara, ... Molecular psychiatry 28 (7), 2878-2893, 2023 | 127 | 2023 |
| Complement dysregulation in the central nervous system during development and disease JD Lee, LG Coulthard, TM Woodruff Seminars in immunology 45, 101340, 2019 | 110 | 2019 |
| Cortical synaptic and dendritic spine abnormalities in a presymptomatic TDP-43 model of amyotrophic lateral sclerosis MJ Fogarty, PM Klenowski, JD Lee, JR Drieberg-Thompson, SE Bartlett, ... Scientific reports 6 (1), 37968, 2016 | 104 | 2016 |
| Pharmacological inhibition of complement C5a‐C5a1 receptor signalling ameliorates disease pathology in the hSOD1G93A mouse model of amyotrophic lateral … JD Lee, V Kumar, JNT Fung, MJ Ruitenberg, PG Noakes, TM Woodruff British journal of pharmacology 174 (8), 689-699, 2017 | 102 | 2017 |
| Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1G93A mouse model of amyotrophic lateral sclerosis JY Lee, JD Lee, S Phipps, PG Noakes, TM Woodruff Journal of neuroinflammation 12, 1-9, 2015 | 93 | 2015 |
| Dysregulation of the complement cascade in the hSOD1G93Atransgenic mouse model of amyotrophic lateral sclerosis JD Lee, NA Kamaruzaman, JNT Fung, SM Taylor, BJ Turner, JD Atkin, ... Journal of neuroinflammation 10, 1-15, 2013 | 91 | 2013 |
| Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors S Pandey, P Kumari, M Baidya, R Kise, Y Cao, H Dwivedi-Agnihotri, ... Molecular cell 81 (22), 4605-4621. e11, 2021 | 90 | 2021 |
| The peripheral immune system and amyotrophic lateral sclerosis PA McCombe, JD Lee, TM Woodruff, RD Henderson Frontiers in neurology 11, 279, 2020 | 89 | 2020 |
| Complement C5aR1 signaling promotes polarization and proliferation of embryonic neural progenitor cells through PKCζ LG Coulthard, OA Hawksworth, R Li, A Balachandran, JD Lee, ... Journal of Neuroscience 37 (22), 5395-5407, 2017 | 82 | 2017 |
| Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditions FH Brennan, JD Lee, MJ Ruitenberg, TM Woodruff Seminars in Immunology 28 (3), 292-308, 2016 | 76 | 2016 |
| Preclinical pharmacokinetics of complement C5a receptor antagonists PMX53 and PMX205 in mice V Kumar, JD Lee, RJ Clark, PG Noakes, SM Taylor, TM Woodruff ACS omega 5 (5), 2345-2354, 2020 | 75 | 2020 |
| Defects in synaptic transmission at the neuromuscular junction precede motor deficits in a TDP‐43Q331K transgenic mouse model of amyotrophic lateral sclerosis KK Chand, KM Lee, JD Lee, H Qiu, EF Willis, NA Lavidis, MA Hilliard, ... The FASEB journal 32 (5), 2676-2689, 2018 | 69 | 2018 |
| Complement C5a-C5aR1 signalling drives skeletal muscle macrophage recruitment in the hSOD1G93A mouse model of amyotrophic lateral sclerosis HA Wang, JD Lee, KM Lee, TM Woodruff, PG Noakes Skeletal Muscle 7, 1-11, 2017 | 60 | 2017 |
| Pharmacological characterisation of small molecule C5aR1 inhibitors in human cells reveals biased activities for signalling and function XX Li, JD Lee, NL Massey, C Guan, AAB Robertson, RJ Clark, ... Biochemical pharmacology 180, 114156, 2020 | 59 | 2020 |
| Complement components are upregulated and correlate with disease progression in the TDP-43Q331K mouse model of amyotrophic lateral sclerosis JD Lee, SC Levin, EF Willis, R Li, TM Woodruff, PG Noakes Journal of neuroinflammation 15, 1-13, 2018 | 56 | 2018 |
| Role for terminal complement activation in amyotrophic lateral sclerosis disease progression TM Woodruff, JD Lee, PG Noakes Proceedings of the National Academy of Sciences 111 (1), E3-E4, 2014 | 55 | 2014 |
Trent M. WoodruffProfessor, The University of QueenslandPatvirtintas el. paštas uq.edu.au