Cytochrome P450 CYP1A1: wider roles in cancer progression and prevention VP Androutsopoulos, AM Tsatsakis, DA Spandidos BMC cancer 9, 1-17, 2009 | 584 | 2009 |
Human exposure to endocrine disrupting chemicals: effects on the male and female reproductive systems S Sifakis, VP Androutsopoulos, AM Tsatsakis, DA Spandidos Environmental toxicology and pharmacology 51, 56-70, 2017 | 476 | 2017 |
A mechanistic overview of health associated effects of low levels of organochlorine and organophosphorous pesticides VP Androutsopoulos, AF Hernandez, J Liesivuori, AM Tsatsakis Toxicology 307, 89-94, 2013 | 253 | 2013 |
Dietary flavonoids in cancer therapy and prevention: substrates and inhibitors of cytochrome P450 CYP1 enzymes VP Androutsopoulos, A Papakyriakou, D Vourloumis, AM Tsatsakis, ... Pharmacology & therapeutics 126 (1), 9-20, 2010 | 248 | 2010 |
Antiproliferative and cytostatic effects of the natural product eupatorin on MDA-MB-468 human breast cancer cells due to CYP1-mediated metabolism V Androutsopoulos, RRJ Arroo, JF Hall, S Surichan, GA Potter Breast Cancer Research 10, 1-12, 2008 | 151 | 2008 |
Comparative CYP1A1 and CYP1B1 substrate and inhibitor profile of dietary flavonoids VP Androutsopoulos, A Papakyriakou, D Vourloumis, DA Spandidos Bioorganic & medicinal chemistry 19 (9), 2842-2849, 2011 | 127 | 2011 |
CYP1-mediated antiproliferative activity of dietary flavonoids in MDA-MB-468 breast cancer cells VP Androutsopoulos, K Ruparelia, RRJ Arroo, AM Tsatsakis, ... Toxicology 264 (3), 162-170, 2009 | 119 | 2009 |
Role of paraoxonase 1 (PON1) in organophosphate metabolism: implications in neurodegenerative diseases VP Androutsopoulos, K Kanavouras, AM Tsatsakis Toxicology and applied pharmacology 256 (3), 418-424, 2011 | 115 | 2011 |
Anticancer effects of the flavonoid diosmetin on cell cycle progression and proliferation of MDA-MB 468 breast cancer cells due to CYP1 activation VP Androutsopoulos, S Mahale, RRJ Arroo, G Potter Oncology reports 21 (6), 1525-1528, 2009 | 109 | 2009 |
Bioactivation of the phytoestrogen diosmetin by CYP1 cytochromes P450 V Androutsopoulos, N Wilsher, RRJ Arroo, GA Potter Cancer letters 274 (1), 54-60, 2009 | 95 | 2009 |
The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and P53/P21 … VP Androutsopoulos, DA Spandidos The Journal of nutritional biochemistry 24 (2), 496-504, 2013 | 92 | 2013 |
Expression profile of CYP1A1 and CYP1B1 enzymes in colon and bladder tumors VP Androutsopoulos, I Spyrou, A Ploumidis, AE Papalampros, ... PloS one 8 (12), e82487, 2013 | 91 | 2013 |
Natural products—friends or foes? D Margină, M Ilie, D Grădinaru, VP Androutsopoulos, D Kouretas, ... Toxicology Letters 236 (3), 154-167, 2015 | 76 | 2015 |
Bioactivation of the citrus flavonoid nobiletin by CYP1 enzymes in MCF7 breast adenocarcinoma cells S Surichan, VP Androutsopoulos, S Sifakis, E Koutala, A Tsatsakis, ... Food and Chemical Toxicology 50 (9), 3320-3328, 2012 | 70 | 2012 |
Anticancer effects of the metabolic products of the resveratrol analogue, DMU-212: structural requirements for potency VP Androutsopoulos, KC Ruparelia, A Papakyriakou, H Filippakis, ... European Journal of Medicinal Chemistry 46 (6), 2586-2595, 2011 | 69 | 2011 |
Cytochrome P450 CYP1 metabolism of hydroxylated flavones and flavonols: Selective bioactivation of luteolin in breast cancer cells NE Wilsher, RR Arroo, MT Matsoukas, AM Tsatsakis, DA Spandidos, ... Food and Chemical Toxicology 110, 383-394, 2017 | 61 | 2017 |
Pesticides and oncogenic modulation E Vakonaki, VP Androutsopoulos, J Liesivuori, AM Tsatsakis, ... Toxicology 307, 42-45, 2013 | 58 | 2013 |
Tangeretin inhibits the proliferation of human breast cancer cells via CYP1A1/CYP1B1 enzyme induction and CYP1A1/CYP1B1–mediated metabolism to the product 4′ hydroxy tangeretin S Surichan, RR Arroo, AM Tsatsakis, VP Androutsopoulos Toxicology in Vitro 50, 274-284, 2018 | 48 | 2018 |
Phytoestrogens as natural prodrugs in cancer prevention: dietary flavonoids RRJ Arroo, V Androutsopoulos, K Beresford, K Ruparelia, S Surichan, ... Phytochemistry Reviews 8, 375-386, 2009 | 47 | 2009 |
Physiological and anthocyanin biosynthesis genes response induced by vanadium stress in mustard genotypes with distinct photosynthetic activity M Imtiaz, MA Mushtaq, MA Nawaz, M Ashraf, MS Rizwan, S Mehmood, ... Environmental Toxicology and Pharmacology 62, 20-29, 2018 | 42 | 2018 |