| Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade P Müller, M Kreuzaler, T Khan, DS Thommen, K Martin, K Glatz, S Savic, ... Science translational medicine 7 (315), 315ra188-315ra188, 2015 | 365 | 2015 |
| Key interactions of surfactants in therapeutic protein formulations: a review TA Khan, HC Mahler, RSK Kishore European journal of pharmaceutics and biopharmaceutics 97, 60-67, 2015 | 277 | 2015 |
| Concentrated dispersions of equilibrium protein nanoclusters that reversibly dissociate into active monomers KP Johnston, JA Maynard, TM Truskett, AU Borwankar, MA Miller, ... ACS nano 6 (2), 1357-1369, 2012 | 142 | 2012 |
| Accurate and predictive antibody repertoire profiling by molecular amplification fingerprinting TA Khan, S Friedensohn, AR Gorter de Vries, J Straszewski, ... Science advances 2 (3), e1501371, 2016 | 138 | 2016 |
| Advanced methodologies in high-throughput sequencing of immune repertoires S Friedensohn, TA Khan, ST Reddy Trends in biotechnology 35 (3), 203-214, 2017 | 136 | 2017 |
| In Vivo Whole Animal Fluorescence Imaging of a Microparticle-Based Oral Vaccine Containing (CuInSexS2–x)/ZnS Core/Shell Quantum Dots MG Panthani, TA Khan, DK Reid, DJ Hellebusch, MR Rasch, JA Maynard, ... Nano letters 13 (9), 4294-4298, 2013 | 127 | 2013 |
| Deep sequencing in library selection projects: what insight does it bring? J Glanville, S D’Angelo, TA Khan, ST Reddy, L Naranjo, F Ferrara, ... Current opinion in structural biology 33, 146-160, 2015 | 88 | 2015 |
| Quantitative assessment of the robustness of next-generation sequencing of antibody variable gene repertoires from immunized mice V Greiff, U Menzel, U Haessler, SC Cook, S Friedensohn, TA Khan, ... BMC immunology 15, 1-14, 2014 | 74 | 2014 |
| Comprehensive evaluation and optimization of amplicon library preparation methods for high-throughput antibody sequencing U Menzel, V Greiff, TA Khan, U Haessler, I Hellmann, S Friedensohn, ... PloS one 9 (5), e96727, 2014 | 66 | 2014 |
| Convergent selection in antibody repertoires is revealed by deep learning S Friedensohn, D Neumeier, TA Khan, L Csepregi, C Parola, ... BioRxiv, 2020.02. 25.965673, 2020 | 50 | 2020 |
| Advancing therapeutic protein discovery and development through comprehensive computational and biophysical characterization L Gentiluomo, HL Svilenov, D Augustijn, I El Bialy, ML Greco, A Kulakova, ... Molecular Pharmaceutics 17 (2), 426-440, 2019 | 50 | 2019 |
| Protein-polydimethylsiloxane particles in liquid vial monoclonal antibody formulations containing poloxamer 188 C Grapentin, C Müller, RSK Kishore, M Adler, I ElBialy, W Friess, ... Journal of pharmaceutical sciences 109 (8), 2393-2404, 2020 | 49 | 2020 |
| Approaches to mitigate the unwanted immunogenicity of therapeutic proteins during drug development LI Salazar-Fontana, DD Desai, TA Khan, RC Pillutla, S Prior, ... The AAPS journal 19, 377-385, 2017 | 42 | 2017 |
| Determination of the density of protein particles using a suspended microchannel resonator E Folzer, TA Khan, R Schmidt, C Finkler, J Huwyler, HC Mahler, ... Journal of pharmaceutical sciences 104 (12), 4034-4040, 2015 | 40 | 2015 |
| Adsorption of non-ionic surfactant and monoclonal antibody on siliconized surface studied by neutron reflectometry Z Zhang, AM Woys, K Hong, C Grapentin, TA Khan, IE Zarraga, ... Journal of colloid and interface science 584, 429-438, 2021 | 30 | 2021 |
| High concentration formulation developability approaches and considerations J Zarzar, T Khan, M Bhagawati, B Weiche, J Sydow-Andersen, ... MAbs 15 (1), 2211185, 2023 | 29 | 2023 |
| Biophysical analysis of lipopolysaccharide formulations for an understanding of the low endotoxin recovery (LER) phenomenon W Correa, K Brandenburg, U Zähringer, K Ravuri, T Khan, ... International Journal of Molecular Sciences 18 (12), 2737, 2017 | 24 | 2017 |
| Immunological principles regulating immunomodulation with biomaterials TA Khan, ST Reddy Acta biomaterialia 10 (4), 1720-1727, 2014 | 24 | 2014 |
| Antibody nanoparticle dispersions formed with mixtures of crowding molecules retain activity and in vivo bioavailability MA Miller, TA Khan, KJ Kaczorowski, BK Wilson, AK Dinin, AU Borwankar, ... Journal of pharmaceutical sciences 101 (10), 3763-3778, 2012 | 22 | 2012 |
| Subcutaneous HER2 antibody formulations J Eng-Wong, W Kirschbrown, T Khan, J Lin, S Alavattam, A Garg, ... US Patent 10,849,849, 2020 | 14 | 2020 |