RAG2 PHD finger couples histone H3 lysine 4 trimethylation with V (D) J recombination AGW Matthews, AJ Kuo, S Ramón-Maiques, S Han, KS Champagne, ... Nature 450 (7172), 1106-1110, 2007 | 539 | 2007 |
NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming AJ Kuo, P Cheung, K Chen, BM Zee, M Kioi, J Lauring, Y Xi, BH Park, ... Molecular cell 44 (4), 609-620, 2011 | 482 | 2011 |
New-onset IgG autoantibodies in hospitalized patients with COVID-19 SE Chang, A Feng, W Meng, SA Apostolidis, E Mack, M Artandi, L Barman, ... Nature communications 12 (1), 5417, 2021 | 469 | 2021 |
The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndrome AJ Kuo, J Song, P Cheung, S Ishibe-Murakami, S Yamazoe, JK Chen, ... Nature 484 (7392), 115-119, 2012 | 402 | 2012 |
The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate Y Li, P Trojer, CF Xu, P Cheung, A Kuo, WJ Drury, Q Qiao, TA Neubert, ... Journal of Biological Chemistry 284 (49), 34283-34295, 2009 | 340 | 2009 |
Single-cell chromatin modification profiling reveals increased epigenetic variations with aging P Cheung, F Vallania, HC Warsinske, M Donato, S Schaffert, SE Chang, ... Cell 173 (6), 1385-1397. e14, 2018 | 336 | 2018 |
Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or … X Shi, I Kachirskaia, KL Walter, JHA Kuo, A Lake, F Davrazou, SM Chan, ... Journal of Biological Chemistry 282 (4), 2450-2455, 2007 | 319 | 2007 |
Lysine methylation of the NF-κB subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-κB signaling D Levy, AJ Kuo, Y Chang, U Schaefer, C Kitson, P Cheung, A Espejo, ... Nature immunology 12 (1), 29, 2011 | 297 | 2011 |
ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation T Hung, O Binda, KS Champagne, AJ Kuo, K Johnson, HY Chang, ... Molecular cell 33 (2), 248-256, 2009 | 248 | 2009 |
The plant homeodomain finger of RAG2 recognizes histone H3 methylated at both lysine-4 and arginine-2 S Ramon-Maiques, AJ Kuo, D Carney, AGW Matthews, MA Oettinger, ... Proceedings of the National Academy of Sciences 104 (48), 18993-18998, 2007 | 239 | 2007 |
The single-cell epigenomic and transcriptional landscape of immunity to influenza vaccination F Wimmers, M Donato, A Kuo, T Ashuach, S Gupta, C Li, M Dvorak, ... Cell 184 (15), 3915-3935. e21, 2021 | 215 | 2021 |
Aire employs a histone-binding module to mediate immunological tolerance, linking chromatin regulation with organ-specific autoimmunity AS Koh, AJ Kuo, SY Park, P Cheung, J Abramson, D Bua, D Carney, ... Proceedings of the National Academy of Sciences 105 (41), 15878-15883, 2008 | 211 | 2008 |
Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor PV Pena, RA Hom, T Hung, H Lin, AJ Kuo, RPC Wong, OM Subach, ... Journal of molecular biology 380 (2), 303-312, 2008 | 152 | 2008 |
Binding of the MLL PHD3 finger to histone H3K4me3 is required for MLL-dependent gene transcription PY Chang, RA Hom, CA Musselman, L Zhu, A Kuo, O Gozani, ... Journal of molecular biology 400 (2), 137-144, 2010 | 135 | 2010 |
Epigenome microarray platform for proteome-wide dissection of chromatin-signaling networks DJ Bua, AJ Kuo, P Cheung, CL Liu, V Migliori, A Espejo, F Casadio, ... PloS one 4 (8), e6789, 2009 | 122 | 2009 |
A molecular threading mechanism underlies Jumonji lysine demethylase KDM2A regulation of methylated H3K36 Z Cheng, P Cheung, AJ Kuo, ET Yukl, CM Wilmot, O Gozani, DJ Patel Genes & development 28 (16), 1758-1771, 2014 | 106 | 2014 |
Integrated, multicohort analysis of systemic sclerosis identifies robust transcriptional signature of disease severity S Lofgren, M Hinchcliff, M Carns, T Wood, K Aren, E Arroyo, P Cheung, ... JCI insight 1 (21), e89073, 2016 | 76 | 2016 |
Chd5 requires PHD-mediated histone 3 binding for tumor suppression S Paul, A Kuo, T Schalch, H Vogel, L Joshua-Tor, WR McCombie, ... Cell reports 3 (1), 92-102, 2013 | 63 | 2013 |
Repression of CTSG, ELANE and PRTN3-mediated histone H3 proteolytic cleavage promotes monocyte-to-macrophage differentiation P Cheung, S Schaffert, SE Chang, M Dvorak, M Donato, C Macaubas, ... Nature immunology 22 (6), 711-722, 2021 | 58 | 2021 |
Single-cell technologies—studying rheumatic diseases one cell at a time P Cheung, P Khatri, PJ Utz, AJ Kuo Nature Reviews Rheumatology 15 (6), 340-354, 2019 | 43 | 2019 |