Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy G Luxán, JC Casanova, B Martínez-Poveda, B Prados, G D'amato, ... Nature medicine 19 (2), 193-201, 2013 | 375 | 2013 |
Probiotics prevent dysbiosis and the rise in blood pressure in genetic hypertension: role of short‐chain fatty acids I Robles‐Vera, M Toral, N de la Visitación, M Sánchez, ... Molecular nutrition & food research 64 (6), 1900616, 2020 | 184 | 2020 |
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism JL Izquierdo-Garcia, P Viswanath, P Eriksson, L Cai, M Radoul, ... Cancer research 75 (15), 2999-3009, 2015 | 139 | 2015 |
Myocardial VHL-HIF signaling controls an embryonic metabolic switch essential for cardiac maturation I Menendez-Montes, B Escobar, B Palacios, MJ Gómez, ... Developmental cell 39 (6), 724-739, 2016 | 138 | 2016 |
A metabolomic approach for diagnosis of experimental sepsis JL Izquierdo-García, N Nin, J Ruíz-Cabello, Y Rojas, M de Paula, ... Intensive care medicine 37, 2023-2032, 2011 | 107 | 2011 |
Metabolic reprogramming in mutant IDH1 glioma cells JL Izquierdo-Garcia, P Viswanath, P Eriksson, MM Chaumeil, RO Pieper, ... PloS one 10 (2), e0118781, 2015 | 98 | 2015 |
β3 adrenergic receptor selective stimulation during ischemia/reperfusion improves cardiac function in translational models through inhibition of mPTP opening in … J García-Prieto, JM García-Ruiz, D Sanz-Rosa, A Pun, A García-Alvarez, ... Basic research in cardiology 109, 1-15, 2014 | 90 | 2014 |
Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase JL Izquierdo-Garcia, LM Cai, MM Chaumeil, P Eriksson, AE Robinson, ... PloS one 9 (9), e108289, 2014 | 89 | 2014 |
Descriptive review of current NMR-based metabolomic data analysis packages JL Izquierdo-García, P Villa, A Kyriazis, L del Puerto-Nevado, ... Progress in Nuclear Magnetic Resonance Spectroscopy 59 (3), 263-270, 2011 | 80 | 2011 |
Pulmonary arterial hypertension affects the rat gut microbiome M Callejo, G Mondejar-Parreño, B Barreira, JL Izquierdo-Garcia, ... Scientific Reports 8 (1), 9681, 2018 | 78 | 2018 |
Brain tumor imaging KM Brindle, JL Izquierdo-García, DY Lewis, RJ Mair, AJ Wright Journal of clinical oncology 35 (21), 2432-2438, 2017 | 73 | 2017 |
GLUT3 upregulation promotes metabolic reprogramming associated with antiangiogenic therapy resistance R Kuang, A Jahangiri, S Mascharak, A Nguyen, A Chandra, PM Flanigan, ... JCI insight 2 (2), e88815, 2017 | 64 | 2017 |
A novel R-package graphic user interface for the analysis of metabonomic profiles JL Izquierdo-García, I Rodríguez, A Kyriazis, P Villa, P Barreiro, M Desco, ... BMC bioinformatics 10, 1-10, 2009 | 63 | 2009 |
2-hydroxyglutarate-mediated autophagy of the endoplasmic reticulum leads to an unusual downregulation of phospholipid biosynthesis in mutant IDH1 gliomas P Viswanath, M Radoul, JL Izquierdo-Garcia, WQ Ong, HA Luchman, ... Cancer research 78 (9), 2290-2304, 2018 | 61 | 2018 |
Probiotic Bifidobacterium breve prevents DOCA‐salt hypertension I Robles‐Vera, N de la Visitación, M Toral, M Sánchez, M Romero, ... The FASEB Journal 34 (10), 13626-13640, 2020 | 57 | 2020 |
Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner P Viswanath, M Radoul, JL Izquierdo-Garcia, HA Luchman, ... Cancer & metabolism 6, 1-13, 2018 | 51 | 2018 |
New biochemical insights into the mechanisms of pulmonary arterial hypertension in humans R Bujak, J Mateo, I Blanco, JL Izquierdo-García, D Dudzik, ... PLoS One 11 (8), e0160505, 2016 | 44 | 2016 |
Identification of novel metabolomic biomarkers in an experimental model of septic acute kidney injury JL Izquierdo-Garcia, N Nin, P Cardinal-Fernandez, Y Rojas, M de Paula, ... American Journal of Physiology-Renal Physiology, 2018 | 41 | 2018 |
HDAC inhibition induces increased choline uptake and elevated phosphocholine levels in MCF7 breast cancer cells CS Ward, P Eriksson, JL Izquierdo-Garcia, AH Brandes, SM Ronen PloS one 8 (4), e62610, 2013 | 39 | 2013 |
Metabolic reprogramming in the heart and lung in a murine model of pulmonary arterial hypertension JL Izquierdo-Garcia, T Arias, Y Rojas, V Garcia-Ruiz, A Santos, ... Frontiers in Cardiovascular Medicine 5, 110, 2018 | 37 | 2018 |